مرور سیستماتیک استرس و بررسی سازه ها و عوامل دخیل در آن
#Stress: #Facts and #Theories through #Literature #Review
#Amir_Mohammad_Shahsavarani, #Esfandiar_Azad_Marz_Abadi, #Maryam_Hakimi_Kalkhoran
Abstract
Introduction: #Human everyday life is full of #stress and strain, so that the present century is called stress era. Unfortunately, here is no literature integration about stress. The aim of the present paper is to make a theoretical integrative consensus in stress modalities.
Methods: The design of the present study was #systematic #review. #Inclusion #criteria were subjective relevance to study keywords (include #stress, #stress_control, #stress_reduction, #social_stress, #community_stress, #group_stress, #stress_increase, #stress_side_effects, #stress_resources, #stress_stages, #stress_types), being published by academic and/or scientific resource, and publication period (between January, 1, 1990 and March, 20, 2015). Using Jadad scale, those clinical trial papers with 2 and upper were selected. #Delphi_method used to form the structure of final results. Results were collected by content analysis.
Results: Eleven major definitions, three main classifications, three fundamental #explanatory perspectives, #occupational stress and related issues, #job #burnout and related issues, biological and #neuropsychological bases, related constructs (#anxiety, #homeostasis, #allostasis), #spiritual/religious/Islamic perspectives, stress outcomes, and multiple relations between stress and culture were presented and discussed.
Conclusion: The ppresent study was an effort to make a theoretical unity of thought in studies about stress. According to the results, it appears that stress cannot be investigated via unimodal studies, and there is a great need to incorporate #BioPsychoSocioSpiritual perspective in analyses and future frameworks of stress studies.
Keywords:
#Stress, #Hypothalamus-Pituitary-Adrenal (HPA) axis, #Homeostasis, #Allostasis, #Cultural stress, BioPsychoSocioSpiritual model, Systematic Review, #Jadad Method, #Delphi Method.
کانال دکتر امیر محمد شهسوارانی
🍃🌹🌸💐🌸🌹🍃
@DrAmirMohammadShahsavarani
[download link]
http://journals.bmsu.ac.ir/ijmr/index.php/ijmr/article/view/107
#Stress: #Facts and #Theories through #Literature #Review
#Amir_Mohammad_Shahsavarani, #Esfandiar_Azad_Marz_Abadi, #Maryam_Hakimi_Kalkhoran
Abstract
Introduction: #Human everyday life is full of #stress and strain, so that the present century is called stress era. Unfortunately, here is no literature integration about stress. The aim of the present paper is to make a theoretical integrative consensus in stress modalities.
Methods: The design of the present study was #systematic #review. #Inclusion #criteria were subjective relevance to study keywords (include #stress, #stress_control, #stress_reduction, #social_stress, #community_stress, #group_stress, #stress_increase, #stress_side_effects, #stress_resources, #stress_stages, #stress_types), being published by academic and/or scientific resource, and publication period (between January, 1, 1990 and March, 20, 2015). Using Jadad scale, those clinical trial papers with 2 and upper were selected. #Delphi_method used to form the structure of final results. Results were collected by content analysis.
Results: Eleven major definitions, three main classifications, three fundamental #explanatory perspectives, #occupational stress and related issues, #job #burnout and related issues, biological and #neuropsychological bases, related constructs (#anxiety, #homeostasis, #allostasis), #spiritual/religious/Islamic perspectives, stress outcomes, and multiple relations between stress and culture were presented and discussed.
Conclusion: The ppresent study was an effort to make a theoretical unity of thought in studies about stress. According to the results, it appears that stress cannot be investigated via unimodal studies, and there is a great need to incorporate #BioPsychoSocioSpiritual perspective in analyses and future frameworks of stress studies.
Keywords:
#Stress, #Hypothalamus-Pituitary-Adrenal (HPA) axis, #Homeostasis, #Allostasis, #Cultural stress, BioPsychoSocioSpiritual model, Systematic Review, #Jadad Method, #Delphi Method.
کانال دکتر امیر محمد شهسوارانی
🍃🌹🌸💐🌸🌹🍃
@DrAmirMohammadShahsavarani
[download link]
http://journals.bmsu.ac.ir/ijmr/index.php/ijmr/article/view/107
مقایسه ناامیدی و خودکارآمدی پناهندگان/مهاجران نوجوان افغان با همسالان ایرانی
#Comparison of #hopelessness and #self-efficacy of #refugee/#immigrant #Afghan #youth with #native #Persian cohorts: A #preliminary #study
Malek Bastami Katouli, Mostafa Ahadi, Javad Afzoun, Mahdi parooi, Habibeh heyrati, #Amir_Mohammad_Shahsavarani
Abstract
Introduction: #International #migrations in the context of war, #civil #war, and #political #instabilities are increasing. #Afghan #refugees in #Iran have high levels of #susceptibility to psychological #difficulties like #dissatisfaction, #sorrow, #frustration, and #anxiety. The aim of the present study was to compare Afghan refugee youths with native Persian youths in #hopelessness and #self_efficacy.
Method: The population comprised all Afghan immigrant and native Persian youths who lived in #Karaj in year 2015. 32 Afghan refugee and 31 native Persian youths were chosen by #purposive #sampling and their hopelessness and self-efficacy were assessed.
Results: #MANOVA showed that Afghan refugee youths achieved significant higher scores in hopelessness (p<.001) and lower scores in self-efficacy (p<.024), compared to Persian native youths.
Discussion and conclusion: These findings indicate that Afghan refugee youths are in higher risk of mental problems than their native Persian cohorts. Therefore, social and psychological services shall urgently pay more attention to improve their specific psychosocial needs as well as #facilitate their #social and #life #skills #training for this #population sector in order to improve their #mental and #psychological #health
Keywords
#Hopelessness, #self_efficacy, #migration, #refugee, #immigrant, #youth, #Afghan #refugees/#immigrants, #mental #health, #Iran.
http://www.ijhcs.com/index.php/ijhcs/article/view/2247
کانال دکتر امیر محمد شهسوارانی
🍃🌹🌸💐🌸🌹🍃
@DrAmirMohammadShahsavarani
#Comparison of #hopelessness and #self-efficacy of #refugee/#immigrant #Afghan #youth with #native #Persian cohorts: A #preliminary #study
Malek Bastami Katouli, Mostafa Ahadi, Javad Afzoun, Mahdi parooi, Habibeh heyrati, #Amir_Mohammad_Shahsavarani
Abstract
Introduction: #International #migrations in the context of war, #civil #war, and #political #instabilities are increasing. #Afghan #refugees in #Iran have high levels of #susceptibility to psychological #difficulties like #dissatisfaction, #sorrow, #frustration, and #anxiety. The aim of the present study was to compare Afghan refugee youths with native Persian youths in #hopelessness and #self_efficacy.
Method: The population comprised all Afghan immigrant and native Persian youths who lived in #Karaj in year 2015. 32 Afghan refugee and 31 native Persian youths were chosen by #purposive #sampling and their hopelessness and self-efficacy were assessed.
Results: #MANOVA showed that Afghan refugee youths achieved significant higher scores in hopelessness (p<.001) and lower scores in self-efficacy (p<.024), compared to Persian native youths.
Discussion and conclusion: These findings indicate that Afghan refugee youths are in higher risk of mental problems than their native Persian cohorts. Therefore, social and psychological services shall urgently pay more attention to improve their specific psychosocial needs as well as #facilitate their #social and #life #skills #training for this #population sector in order to improve their #mental and #psychological #health
Keywords
#Hopelessness, #self_efficacy, #migration, #refugee, #immigrant, #youth, #Afghan #refugees/#immigrants, #mental #health, #Iran.
http://www.ijhcs.com/index.php/ijhcs/article/view/2247
کانال دکتر امیر محمد شهسوارانی
🍃🌹🌸💐🌸🌹🍃
@DrAmirMohammadShahsavarani
#سودمندی #آموزش های #روانی-#مذهبی در #بهبود #رفتارسازمانی و #سلامت #روان
THE #EFFICACY OF #PSYCHO-#RELIGIOUS #TRAINING ON #IMPROVEMENT OF #ORGANIZATIONAL #BEHAVIOR AND #MENTAL #HEALTH
#A_M_Shahsavarani, E. #Zoghifard, M. E. #Mishamandani, M. #Mahmoodabadi, A. #Mohammadi, K. #Sattari.
Abstract
Introduction: One of the most important issues of organizations in the modern age is to maximize their #efficiency via #improvement of #organizational #behavior. Organizational behavior is #directly #linked to #mental #health and recent #studies have shown the major role of #religion in #maintaining mental health of people. The aim of the study was to #investigate the efficacy of #psycho_religious training on improvement of the organizational behavior and mental health.
Method: A group of 120 white collar #personnel (60 females and 60 males) chosen by #cluster #sampling & #divided randomly into two equal #experimental and control groups (n=60; 30 female & 30 male). The #experimental #trial was the #administration of the psycho-religious training for three weeks, which consisted of twelve 120-minute #discussion_group sessions during 12 weeks. In order to assess the mental health, #GHQ_28 was administered as pre-test and post-test in both groups.
Findings: The results of the #independent and dependent t-test indicate the #positive #effect of psycho-religious training on the mental health of the participants in the experimental group in indices of #anxiety/#insomnia, severe #depression, and total health (p<.05). There were no #significant #gender differences.
Discussion and conclusion: These #findings suggest that incorporation of #religious training within the usual #modalities of #psychological interventions would be beneficial and increase the levels of mental health and organizational behavior. Implications and suggestions are discussed.
Keywords:
#Psycho_religious #education, #psychoeducation, #health, #religion, #organizational #behavior, #mental #health, #white #collar, #labor #force.
http://www.jfas.info/index.php/jfas/article/view/1079
کانال دکتر امیر محمد شهسوارانی
🍃🌹🌸💐🌸🌹🍃
@DrAmirMohammadShahsavarani
THE #EFFICACY OF #PSYCHO-#RELIGIOUS #TRAINING ON #IMPROVEMENT OF #ORGANIZATIONAL #BEHAVIOR AND #MENTAL #HEALTH
#A_M_Shahsavarani, E. #Zoghifard, M. E. #Mishamandani, M. #Mahmoodabadi, A. #Mohammadi, K. #Sattari.
Abstract
Introduction: One of the most important issues of organizations in the modern age is to maximize their #efficiency via #improvement of #organizational #behavior. Organizational behavior is #directly #linked to #mental #health and recent #studies have shown the major role of #religion in #maintaining mental health of people. The aim of the study was to #investigate the efficacy of #psycho_religious training on improvement of the organizational behavior and mental health.
Method: A group of 120 white collar #personnel (60 females and 60 males) chosen by #cluster #sampling & #divided randomly into two equal #experimental and control groups (n=60; 30 female & 30 male). The #experimental #trial was the #administration of the psycho-religious training for three weeks, which consisted of twelve 120-minute #discussion_group sessions during 12 weeks. In order to assess the mental health, #GHQ_28 was administered as pre-test and post-test in both groups.
Findings: The results of the #independent and dependent t-test indicate the #positive #effect of psycho-religious training on the mental health of the participants in the experimental group in indices of #anxiety/#insomnia, severe #depression, and total health (p<.05). There were no #significant #gender differences.
Discussion and conclusion: These #findings suggest that incorporation of #religious training within the usual #modalities of #psychological interventions would be beneficial and increase the levels of mental health and organizational behavior. Implications and suggestions are discussed.
Keywords:
#Psycho_religious #education, #psychoeducation, #health, #religion, #organizational #behavior, #mental #health, #white #collar, #labor #force.
http://www.jfas.info/index.php/jfas/article/view/1079
کانال دکتر امیر محمد شهسوارانی
🍃🌹🌸💐🌸🌹🍃
@DrAmirMohammadShahsavarani
♻️ #پیشگیری و درمان #ترس، #هراس و #اختلال استرس پس آسیبی (#PTSD) در #انسان توسط #آنتی-بیوتیک های رایج
#Blocking human #fear #memory with the #matrix #metalloproteinase #inhibitor #doxycycline
🔬پژوهشگران نوروساینس دانشگاه زوریج و یونیورسیتی کالج لندن در پژوهشی مشترک دریافتند که کاربرد آنتی بیوتیک های رایج درمان عفونت های میکروبی می توانند #حافظه #رخدادهای #استرس زا و ترسناک را مختل کنند به گونه ای که تداعی های منفی در مغز شکل نگیرند.
🔍در این پژوهش که 76 زن و مرد #داوطلب #غیربالینی در آن شرکت داشتند، مشخص شد مصرف آنتی بیوتیک #داکسی_سایکلین منجر به کاهش 60 درصدی تداعی های ترسناک در ذهن افراد می شود بطوری که حافظه آنها در #شرطی سازی #پاولفی برای خاطرات استرس زا و ترسناک شکل نمی گیرد. اما مصرف این #آنتی_بیوتیک بر سایر جنبه های #شناختی (#حافظه_حسی و #توجه) تاثیری ندارد.
📚در این افراد #حافظه تجربه #ترسناک و استرس زا پاک نشده بود، بلکه توانمندی #تداعی_شرطی #کلاسیک در آنها کاهش یافته بود. یادگیری ترس و تداعی تعمیم یافته آن عامل اصلی در اختلالات اضطرابی بویژه PTSD است؛ اختلالی ناتوان کننده که بویژه جزو عوارض #جنگ، #بلایای #طبیعی، #فجایع و #بحران ها بوده و بطور معمول تا پایان عمر با فرد مبتلا همراه است. پژوهشگران امیدوارند در گام های بعدی با آزمایش این روش بر نمونه های بالینی، نتایج متقنی در این حوزه بدست آورند تا بتوان درمانهای ساده تر و پایاتری برای اختلالات #اضطرابی تدوین نمود.
Abstract
#Learning to #predict #threat is a #fundamental ability of many biological organisms, and a laboratory model for #anxiety disorders. Interfering with such #memories in humans would be of high clinical relevance. On the basis of studies in cell cultures and slice preparations, it is hypothesised that synaptic remodelling required for threat learning involves the #extracellular enzyme matrix metalloproteinase (#MMP) 9. However, in vivo evidence for this proposal is lacking. Here we investigate human #Pavlovian fear conditioning under the #blood–brain barrier crossing MMP# inhibitor #doxycyline in a pre-registered, randomised, double-blind, #placebo-controlled trial. We find that recall of threat memory, measured with fear-potentiated startle 7 days after acquisition, is attenuated by ~60% in individuals who were under doxycycline during #acquisition. This threat memory impairment is also reflected in increased behavioural surprise signals to the conditioned stimulus during subsequent re-learning, and already late during initial acquisition. Our findings support an emerging view that #extracellular #signalling pathways are crucially required for threat memory formation. Furthermore, they suggest novel #pharmacological methods for primary prevention and treatment of #posttraumatic stress disorder (#PTSD).
لینک منبع 👇🏻(further reading)👇🏻
http://www.nature.com/mp/journal/vaop/ncurrent/full/mp201765a.html
✅(در صورت جذابیت و علاقمندی به موضوع، مطلب را برای دیگران نیز بازنشر فرمایید).
📢کانال #دکترامیرمحمدشهسوارانی
🍃🌹🌸💐🌸🌹🍃
@DrAmirMohammadShahsavarani
#Blocking human #fear #memory with the #matrix #metalloproteinase #inhibitor #doxycycline
🔬پژوهشگران نوروساینس دانشگاه زوریج و یونیورسیتی کالج لندن در پژوهشی مشترک دریافتند که کاربرد آنتی بیوتیک های رایج درمان عفونت های میکروبی می توانند #حافظه #رخدادهای #استرس زا و ترسناک را مختل کنند به گونه ای که تداعی های منفی در مغز شکل نگیرند.
🔍در این پژوهش که 76 زن و مرد #داوطلب #غیربالینی در آن شرکت داشتند، مشخص شد مصرف آنتی بیوتیک #داکسی_سایکلین منجر به کاهش 60 درصدی تداعی های ترسناک در ذهن افراد می شود بطوری که حافظه آنها در #شرطی سازی #پاولفی برای خاطرات استرس زا و ترسناک شکل نمی گیرد. اما مصرف این #آنتی_بیوتیک بر سایر جنبه های #شناختی (#حافظه_حسی و #توجه) تاثیری ندارد.
📚در این افراد #حافظه تجربه #ترسناک و استرس زا پاک نشده بود، بلکه توانمندی #تداعی_شرطی #کلاسیک در آنها کاهش یافته بود. یادگیری ترس و تداعی تعمیم یافته آن عامل اصلی در اختلالات اضطرابی بویژه PTSD است؛ اختلالی ناتوان کننده که بویژه جزو عوارض #جنگ، #بلایای #طبیعی، #فجایع و #بحران ها بوده و بطور معمول تا پایان عمر با فرد مبتلا همراه است. پژوهشگران امیدوارند در گام های بعدی با آزمایش این روش بر نمونه های بالینی، نتایج متقنی در این حوزه بدست آورند تا بتوان درمانهای ساده تر و پایاتری برای اختلالات #اضطرابی تدوین نمود.
Abstract
#Learning to #predict #threat is a #fundamental ability of many biological organisms, and a laboratory model for #anxiety disorders. Interfering with such #memories in humans would be of high clinical relevance. On the basis of studies in cell cultures and slice preparations, it is hypothesised that synaptic remodelling required for threat learning involves the #extracellular enzyme matrix metalloproteinase (#MMP) 9. However, in vivo evidence for this proposal is lacking. Here we investigate human #Pavlovian fear conditioning under the #blood–brain barrier crossing MMP# inhibitor #doxycyline in a pre-registered, randomised, double-blind, #placebo-controlled trial. We find that recall of threat memory, measured with fear-potentiated startle 7 days after acquisition, is attenuated by ~60% in individuals who were under doxycycline during #acquisition. This threat memory impairment is also reflected in increased behavioural surprise signals to the conditioned stimulus during subsequent re-learning, and already late during initial acquisition. Our findings support an emerging view that #extracellular #signalling pathways are crucially required for threat memory formation. Furthermore, they suggest novel #pharmacological methods for primary prevention and treatment of #posttraumatic stress disorder (#PTSD).
لینک منبع 👇🏻(further reading)👇🏻
http://www.nature.com/mp/journal/vaop/ncurrent/full/mp201765a.html
✅(در صورت جذابیت و علاقمندی به موضوع، مطلب را برای دیگران نیز بازنشر فرمایید).
📢کانال #دکترامیرمحمدشهسوارانی
🍃🌹🌸💐🌸🌹🍃
@DrAmirMohammadShahsavarani
Nature
Molecular Psychiatry - Blocking human fear memory with the matrix metalloproteinase inhibitor doxycycline
Molecular Psychiatry publishes work aimed at elucidating biological mechanisms underlying psychiatric disorders and their treatment
♻️ #پیشگیری و درمان اختلالات #افسردگی و #اضطراب #پسازایمانی با مصرف روزانه #ماست در #زنان #باردار
Effect of #Lactobacillus #rhamnosus #HN001 in #Pregnancy on #Postpartum Symptoms of #Depression and #Anxiety: A #Randomised #Double-blind #Placebo-controlled #Trial
پژوهشگران طب اطفال دانشگاه های آوکلند و اُتاگو 🇳🇿 در پژوهشی که به تازگی صورت گرفته است دریافتند مصرف مواد #پروبیوتیک (#لاکتوباسیلوس) موجود در #ماست در دوران #بارداری منجر به #پیشگیری و #کاهش #اختلالات #افسردگی و #اضطراب #پسازایمانی می شود.
🔬در این پژوهش آزمایشی که بر 423 زن باردار صورت گرفت، داوطلبان از هفته 15 بارداری تا ماه ششم پس از زایمان (در صورت #شیردادن از #سینه به فرزند) مواد پروبیوتیک مصرف کردند و سطح اضطراب و افسردگی آنها توسط پرسشنامه افسردگی پسازایمانی #ادینبورگ و پرسشنامه #حالت-صفت اضطراب سنجیده شد.
📚نتایج نشان دادند، زنانی که بطور روزانه در طی پژوهش مواد پروبیوتیک مصرف می کردند به شکل معناداری سطوح اضطراب و افسردگی کمتری در دوران بعد بارداری داشتند. این گروه پژوهشی به عنوان توصیه برای بهبود سلامت روانی مادران باردار و نیز کاهش مسایل بعد زایمان، پیشنهاد اکید بر مصرف روزانه ماست دارند.
🔆پژوهش های پیشین نیز تاثیرات مثبت ماست بر درمان بیماری پارکینسن، اختلالات استرسی، اضطرابی، و خلقی را به اثبات رسانده بودند.
Abstract
Objective: The aim of this study was to evaluate the effect of Lactobacillus rhamnosus HN001 (HN001) given in pregnancy and postpartum on symptoms of maternal depression and anxiety in the postpartum period. This was a secondary outcome, the primary outcome being eczema in the offspring at 12 months of age.
Design, Setting, Participants: A randomised, double-blind, placebo-controlled trial of the effect of HN001 on postnatal mood was conducted in 423 women in Auckland and Wellington, New Zealand. Women were recruited at 14–16 weeks gestation.
Intervention: Women were randomised to receive either placebo or HN001 daily from enrolment until 6 months postpartum if breastfeeding.
Findings: 423 women were recruited between December 2012 and November 2014. 212 women were randomised to HN001 and 211 to placebo. 380 women (89.8%) completed the questionnaire on psychological outcomes, 193 (91.0%) in the treatment group and 187 (88.6%) in the placebo group. Mothers in the probiotic treatment group reported significantly lower depression scores (HN001 mean = 7·7 (SD = 5·4), placebo 9·0 (6·0); effect size -1·2, (95% CI -2·3, -0·1), p = 0·037) and anxiety scores (HN001 12·0 (4·0), placebo 13·0 (4·0); effect size -1·0 (-1·9, -0·2), p = 0·014) than those in the placebo group. Rates of clinically relevant anxiety on screening (score > 15) were significantly lower in the HN001 treated mothers (OR = 0·44 (0·26, 0·73), p = 0·002).
Interpretation: Women who received HN001 had significantly lower depression and anxiety scores in the postpartum period. This probiotic may be useful for the prevention or treatment of symptoms of depression and anxiety postpartum.
لینک منبع 👇🏻(further reading)👇🏻
www.ebiomedicine.com/article/S2352-3964(17)30366-3/fulltext
✅(در صورت جذابیت و علاقمندی به موضوع، مطلب را برای دیگران نیز بازنشر فرمایید).
📢کانال #دکترامیرمحمدشهسوارانی
🍃🌹🌸💐🌸🌹🍃
@DrAmirMohammadShahsavarani
Effect of #Lactobacillus #rhamnosus #HN001 in #Pregnancy on #Postpartum Symptoms of #Depression and #Anxiety: A #Randomised #Double-blind #Placebo-controlled #Trial
پژوهشگران طب اطفال دانشگاه های آوکلند و اُتاگو 🇳🇿 در پژوهشی که به تازگی صورت گرفته است دریافتند مصرف مواد #پروبیوتیک (#لاکتوباسیلوس) موجود در #ماست در دوران #بارداری منجر به #پیشگیری و #کاهش #اختلالات #افسردگی و #اضطراب #پسازایمانی می شود.
🔬در این پژوهش آزمایشی که بر 423 زن باردار صورت گرفت، داوطلبان از هفته 15 بارداری تا ماه ششم پس از زایمان (در صورت #شیردادن از #سینه به فرزند) مواد پروبیوتیک مصرف کردند و سطح اضطراب و افسردگی آنها توسط پرسشنامه افسردگی پسازایمانی #ادینبورگ و پرسشنامه #حالت-صفت اضطراب سنجیده شد.
📚نتایج نشان دادند، زنانی که بطور روزانه در طی پژوهش مواد پروبیوتیک مصرف می کردند به شکل معناداری سطوح اضطراب و افسردگی کمتری در دوران بعد بارداری داشتند. این گروه پژوهشی به عنوان توصیه برای بهبود سلامت روانی مادران باردار و نیز کاهش مسایل بعد زایمان، پیشنهاد اکید بر مصرف روزانه ماست دارند.
🔆پژوهش های پیشین نیز تاثیرات مثبت ماست بر درمان بیماری پارکینسن، اختلالات استرسی، اضطرابی، و خلقی را به اثبات رسانده بودند.
Abstract
Objective: The aim of this study was to evaluate the effect of Lactobacillus rhamnosus HN001 (HN001) given in pregnancy and postpartum on symptoms of maternal depression and anxiety in the postpartum period. This was a secondary outcome, the primary outcome being eczema in the offspring at 12 months of age.
Design, Setting, Participants: A randomised, double-blind, placebo-controlled trial of the effect of HN001 on postnatal mood was conducted in 423 women in Auckland and Wellington, New Zealand. Women were recruited at 14–16 weeks gestation.
Intervention: Women were randomised to receive either placebo or HN001 daily from enrolment until 6 months postpartum if breastfeeding.
Findings: 423 women were recruited between December 2012 and November 2014. 212 women were randomised to HN001 and 211 to placebo. 380 women (89.8%) completed the questionnaire on psychological outcomes, 193 (91.0%) in the treatment group and 187 (88.6%) in the placebo group. Mothers in the probiotic treatment group reported significantly lower depression scores (HN001 mean = 7·7 (SD = 5·4), placebo 9·0 (6·0); effect size -1·2, (95% CI -2·3, -0·1), p = 0·037) and anxiety scores (HN001 12·0 (4·0), placebo 13·0 (4·0); effect size -1·0 (-1·9, -0·2), p = 0·014) than those in the placebo group. Rates of clinically relevant anxiety on screening (score > 15) were significantly lower in the HN001 treated mothers (OR = 0·44 (0·26, 0·73), p = 0·002).
Interpretation: Women who received HN001 had significantly lower depression and anxiety scores in the postpartum period. This probiotic may be useful for the prevention or treatment of symptoms of depression and anxiety postpartum.
لینک منبع 👇🏻(further reading)👇🏻
www.ebiomedicine.com/article/S2352-3964(17)30366-3/fulltext
✅(در صورت جذابیت و علاقمندی به موضوع، مطلب را برای دیگران نیز بازنشر فرمایید).
📢کانال #دکترامیرمحمدشهسوارانی
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@DrAmirMohammadShahsavarani