Baseline #Gut Metagenomic Functional Gene Signature Associated with Variable #Weight Loss Responses following a Healthy Lifestyle Intervention in Humans
https://2medical.news/2021/09/23/baseline-gut-metagenomic-functional-gene-signature-associated-with-variable-weight-loss-responses-following-a-healthy-lifestyle-intervention-in-humans/
https://2medical.news/2021/09/23/baseline-gut-metagenomic-functional-gene-signature-associated-with-variable-weight-loss-responses-following-a-healthy-lifestyle-intervention-in-humans/
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Baseline #Gut Metagenomic Functional Gene Signature Associated with Variable #Weight Loss Responses following a Healthy Lifestyle…
Recent human feeding studies have shown how the baseline taxonomic composition of the gut microbiome can determine responses to weight loss interventions. However, the functional determinants under…
Computational drug repositioning of #atorvastatin for ulcerative #colitis
https://2medical.news/2021/09/24/computational-drug-repositioning-of-atorvastatin-for-ulcerative-colitis/
https://2medical.news/2021/09/24/computational-drug-repositioning-of-atorvastatin-for-ulcerative-colitis/
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Computational drug repositioning of #atorvastatin for ulcerative #colitis
Ulcerative colitis (UC) is a chronic inflammatory disorder with limited effective therapeutic options for long-term treatment and disease maintenance. We hypothesized that a multi-cohort analysis o…
#Obesity treatment: #Weight loss versus increasing #fitness and physical activity for reducing health risks
https://2medical.news/2021/09/24/obesity-treatment-weight-loss-versus-increasing-fitness-and-physical-activity-for-reducing-health-risks/
https://2medical.news/2021/09/24/obesity-treatment-weight-loss-versus-increasing-fitness-and-physical-activity-for-reducing-health-risks/
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#Obesity treatment: #Weight loss versus increasing #fitness and physical activity for reducing health risks
We propose a weight-neutral strategy for obesity treatment on the following grounds: (1) the mortality risk associated with obesity is largely attenuated or eliminated by moderate-to-high levels of…
Role and Mechanism of Gut #Microbiota in Human #Disease
https://2medical.news/2021/09/25/role-and-mechanism-of-gut-microbiota-in-human-disease/
https://2medical.news/2021/09/25/role-and-mechanism-of-gut-microbiota-in-human-disease/
2Medical.News
Role and Mechanism of Gut #Microbiota in Human #Disease
The human gut microbiome is a huge microbial community that plays an irreplaceable role in human life. With the further development of research, the influence of intestinal flora on human diseases …
A Meta-Analysis on the Global Prevalence, Risk factors and Screening of Coronary #Heart Disease in Non-alcoholic #Fatty Liver Disease
https://2medical.news/2021/09/25/a-meta-analysis-on-the-global-prevalence-risk-factors-and-screening-of-coronary-heart-disease-in-non-alcoholic-fatty-liver-disease/
https://2medical.news/2021/09/25/a-meta-analysis-on-the-global-prevalence-risk-factors-and-screening-of-coronary-heart-disease-in-non-alcoholic-fatty-liver-disease/
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A Meta-Analysis on the Global Prevalence, Risk factors and Screening of Coronary #Heart Disease in Non-alcoholic #Fatty Liver Disease
Background and AimsCardiovascular disease remains the leading cause of death in patients with non-alcoholic fatty liver disease (NAFLD). Studies examining the association of coronary heart disease …
The relation between #oxytocin receptor gene polymorphisms, adult attachment and #Instagram sociability: An exploratory analysis
https://2medical.news/2021/09/26/the-relation-between-oxytocin-receptor-gene-polymorphisms-adult-attachment-and-instagram-sociability-an-exploratory-analysis/
https://2medical.news/2021/09/26/the-relation-between-oxytocin-receptor-gene-polymorphisms-adult-attachment-and-instagram-sociability-an-exploratory-analysis/
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The relation between #oxytocin receptor gene polymorphisms, adult attachment and #Instagram sociability: An exploratory analysis
AbstractOxytocin is a primary neuropeptide which coordinates affiliative behavior. Previous researchers pointed to the association between genetic vulnerability on Oxytocin Receptor Gene (OXTR) and…
Adenoviral Vector DNA- and #SARS-CoV-2 mRNA-Based Covid-19 Vaccines: Possible Integration into the Human #Genome – Are Adenoviral Genes Expressed in Vector-based Vaccines?
https://2medical.news/2021/09/26/adenoviral-vector-dna-and-sars-cov-2-mrna-based-covid-19-vaccines-possible-integration-into-the-human-genome-are-adenoviral-genes-expressed-in-vector-based-vaccines/
https://2medical.news/2021/09/26/adenoviral-vector-dna-and-sars-cov-2-mrna-based-covid-19-vaccines-possible-integration-into-the-human-genome-are-adenoviral-genes-expressed-in-vector-based-vaccines/
2Medical.News
Adenoviral Vector DNA- and #SARS-CoV-2 mRNA-Based Covid-19 Vaccines: Possible Integration into the Human #Genome – Are Adenoviral…
This brief review was presented here to facilitate an independent and more balanced discussion on the potential risks due to the presence of adenovirus vector DNA (AstraZeneca, Johnson & Johnso…
Efficacy and safety of PXL770, a direct AMP kinase activator, for the treatment of non-alcoholic #fatty liver disease (STAMP-NAFLD): a randomised, double-blind, placebo-controlled, phase 2a study
https://2medical.news/2021/09/27/efficacy-and-safety-of-pxl770-a-direct-amp-kinase-activator-for-the-treatment-of-non-alcoholic-fatty-liver-disease-stamp-nafld-a-randomised-double-blind-placebo-controlled-phase-2a-study/
https://2medical.news/2021/09/27/efficacy-and-safety-of-pxl770-a-direct-amp-kinase-activator-for-the-treatment-of-non-alcoholic-fatty-liver-disease-stamp-nafld-a-randomised-double-blind-placebo-controlled-phase-2a-study/
2Medical.News
Efficacy and safety of PXL770, a direct AMP kinase activator, for the treatment of non-alcoholic #fatty liver disease (STAMP-NAFLD):…
AMP kinase (AMPK) is an energy sensor implicated in regulation of lipid metabolism, inflammation, and insulin sensitivity. We aimed to assess efficacy and safety of PXL770, a novel direct AMPK acti…
#Anakinra for severe forms of #COVID-19: a cohort study
https://2medical.news/2021/09/27/anakinra-for-severe-forms-of-covid-19-a-cohort-study/
https://2medical.news/2021/09/27/anakinra-for-severe-forms-of-covid-19-a-cohort-study/
2Medical.News
#Anakinra for severe forms of #COVID-19: a cohort study
Coronaviruses can induce the production of interleukin (IL)-1β, IL-6, tumour necrosis factor, and other cytokines implicated in autoinflammatory disorders. It has been postulated that anakinra, a r…
Incident Major #Depressive Disorder Predicted by Three Measures of Insulin #Resistance: A Dutch Cohort Study
https://2medical.news/2021/09/28/incident-major-depressive-disorder-predicted-by-three-measures-of-insulin-resistance-a-dutch-cohort-study/
https://2medical.news/2021/09/28/incident-major-depressive-disorder-predicted-by-three-measures-of-insulin-resistance-a-dutch-cohort-study/
2Medical.News
Incident Major #Depressive Disorder Predicted by Three Measures of Insulin #Resistance: A Dutch Cohort Study
Major depressive disorder is the leading cause of disability worldwide. Yet, there remain significant challenges in predicting new cases of major depression and devising strategies to prevent the d…
Spatial organization of #protein aggregates on red #blood cells as physical biomarkers of #Alzheimer’s disease pathology
https://2medical.news/2021/09/28/spatial-organization-of-protein-aggregates-on-red-blood-cells-as-physical-biomarkers-of-alzheimers-disease-pathology/
https://2medical.news/2021/09/28/spatial-organization-of-protein-aggregates-on-red-blood-cells-as-physical-biomarkers-of-alzheimers-disease-pathology/
2Medical.News
Spatial organization of #protein aggregates on red #blood cells as physical biomarkers of #Alzheimer’s disease pathology
Quantifying physical differences of protein aggregates implicated in Alzheimer’s disease (AD), in blood, could provide crucial information on disease stages. Here, red blood cells (RBCs) from 50 pa…
#Aging and comorbidities influence the risk of hospitalization and mortality in #diabetic patients experiencing severe hypoglycemia
https://2medical.news/2021/09/29/aging-and-comorbidities-influence-the-risk-of-hospitalization-and-mortality-in-diabetic-patients-experiencing-severe-hypoglycemia/
https://2medical.news/2021/09/29/aging-and-comorbidities-influence-the-risk-of-hospitalization-and-mortality-in-diabetic-patients-experiencing-severe-hypoglycemia/
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#Aging and comorbidities influence the risk of hospitalization and mortality in #diabetic patients experiencing severe hypoglycemia
Severe hypoglycemia requiring access to the Emergency Department is more frequent in older patients with multiple comorbidities.•Risk of hospitalization and mortality within one year since the hypo…
Effects of #Lifestyle Modification on Patients With Resistant #Hypertension: Results of the TRIUMPH Randomized Clinical Trial
https://2medical.news/2021/09/29/effects-of-lifestyle-modification-on-patients-with-resistant-hypertension-results-of-the-triumph-randomized-clinical-trial/
https://2medical.news/2021/09/29/effects-of-lifestyle-modification-on-patients-with-resistant-hypertension-results-of-the-triumph-randomized-clinical-trial/
2Medical.News
Effects of #Lifestyle Modification on Patients With Resistant #Hypertension: Results of the TRIUMPH Randomized Clinical Trial
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Cross-sectional associations of schoolchildren’s #fruit and #vegetable consumption, and meal choices, with their mental well-being: a cross-sectional study
https://2medical.news/2021/09/30/cross-sectional-associations-of-schoolchildrens-fruit-and-vegetable-consumption-and-meal-choices-with-their-mental-well-being-a-cross-sectional-study/
https://2medical.news/2021/09/30/cross-sectional-associations-of-schoolchildrens-fruit-and-vegetable-consumption-and-meal-choices-with-their-mental-well-being-a-cross-sectional-study/
2Medical.News
Cross-sectional associations of schoolchildren’s #fruit and #vegetable consumption, and meal choices, with their mental well-being:…
Poor mental well-being is a major issue for young people and is likely to have long-term negative consequences. The contribution of nutrition is underexplored. We, therefore, investigated the assoc…
Synthesis of human #amyloid restricted to #liver results in an #Alzheimer disease–like neurodegenerative phenotype
https://2medical.news/2021/09/30/synthesis-of-human-amyloid-restricted-to-liver-results-in-an-alzheimer-disease-like-neurodegenerative-phenotype/
https://2medical.news/2021/09/30/synthesis-of-human-amyloid-restricted-to-liver-results-in-an-alzheimer-disease-like-neurodegenerative-phenotype/
2Medical.News
Synthesis of human #amyloid restricted to #liver results in an #Alzheimer disease–like neurodegenerative phenotype
Several lines of study suggest that peripheral metabolism of amyloid beta (Aß) is associated with risk for Alzheimer disease (AD). In blood, greater than 90% of Aß is complexed as an apolipoprotein…
Assessment of #Allergic and #Anaphylactic Reactions to mRNA #COVID-19 Vaccines With Confirmatory Testing in a US Regional Health System
https://2medical.news/2021/10/01/assessment-of-allergic-and-anaphylactic-reactions-to-mrna-covid-19-vaccines-with-confirmatory-testing-in-a-us-regional-health-system/
https://2medical.news/2021/10/01/assessment-of-allergic-and-anaphylactic-reactions-to-mrna-covid-19-vaccines-with-confirmatory-testing-in-a-us-regional-health-system/
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Assessment of #Allergic and #Anaphylactic Reactions to mRNA #COVID-19 Vaccines With Confirmatory Testing in a US Regional Health…
Objective To characterize the immunologic mechanisms underlying allergic reactions to these vaccines. Design, Setting, and Participants This case series included 22 patients with suspected allergic…
Vitamin #D supplementation reduces the risk of #fall in the vitamin D deficient elderly: an updated systematic review and meta-analysis
https://2medical.news/2021/10/01/vitamin-d-supplementation-reduces-the-risk-of-fall-in-the-vitamin-d-deficient-elderly-an-updated-systematic-review-and-meta-analysis/
https://2medical.news/2021/10/01/vitamin-d-supplementation-reduces-the-risk-of-fall-in-the-vitamin-d-deficient-elderly-an-updated-systematic-review-and-meta-analysis/
2Medical.News
Vitamin #D supplementation reduces the risk of #fall in the vitamin D deficient elderly: an updated systematic review and meta…
Vitamin D supplementation has been widely recommended to prevent falls. However, considerable controversy exists regarding the association of such supplementation and fall risk. Previous meta-analy…
#Dysbiosis of the gut microbiome impairs mouse skeletal #muscle adaptation to exercise
https://2medical.news/2021/10/02/dysbiosis-of-the-gut-microbiome-impairs-mouse-skeletal-muscle-adaptation-to-exercise/
https://2medical.news/2021/10/02/dysbiosis-of-the-gut-microbiome-impairs-mouse-skeletal-muscle-adaptation-to-exercise/
2Medical.News
#Dysbiosis of the gut microbiome impairs mouse skeletal #muscle adaptation to exercise
Dysbiosis of the gut microbiome caused by continuous antibiotic treatment did not affect running activity.Continuous treatment with antibiotics did not result in systemic inflammation as indicated …
Metabolic associated fatty #liver disease is the risk factor for chronic #kidney disease
https://2medical.news/2021/10/03/metabolic-associated-fatty-liver-disease-is-the-risk-factor-for-chronic-kidney-disease/
https://2medical.news/2021/10/03/metabolic-associated-fatty-liver-disease-is-the-risk-factor-for-chronic-kidney-disease/
2Medical.News
Metabolic associated fatty #liver disease is the risk factor for chronic #kidney disease
Background & AimsTo clarify the relationship between metabolic dysfunction-associated fatty liver disease (MAFLD) and chronic kidney disease (CKD). MethodsThe participants were divided into fou…
Dietary #spinach reshapes the gut #microbiome in an Apc-mutant genetic background: mechanistic insights from integrated multi-omics
https://2medical.news/2021/10/04/dietary-spinach-reshapes-the-gut-microbiome-in-an-apc-mutant-genetic-background-mechanistic-insights-from-integrated-multi-omics/
https://2medical.news/2021/10/04/dietary-spinach-reshapes-the-gut-microbiome-in-an-apc-mutant-genetic-background-mechanistic-insights-from-integrated-multi-omics/
2Medical.News
Dietary #spinach reshapes the gut #microbiome in an Apc-mutant genetic background: mechanistic insights from integrated multi-omics
ABSTRACTComplex interrelationships govern the dynamic interactions between gut microbes, the host, and exogenous drivers of disease outcome. A multi-omics approach to cancer prevention by spinach (…
Incidence, co-occurrence, and evolution of long- #COVID features: A 6-month retrospective cohort study of 273,618 survivors of COVID-19
https://2medical.news/2021/10/04/incidence-co-occurrence-and-evolution-of-long-covid-features-a-6-month-retrospective-cohort-study-of-273618-survivors-of-covid-19/
https://2medical.news/2021/10/04/incidence-co-occurrence-and-evolution-of-long-covid-features-a-6-month-retrospective-cohort-study-of-273618-survivors-of-covid-19/
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Incidence, co-occurrence, and evolution of long- #COVID features: A 6-month retrospective cohort study of 273,618 survivors of…
Long-COVID refers to a variety of symptoms affecting different organs reported by people following Coronavirus Disease 2019 (COVID-19) infection. To date, there have been no robust estimates of the…