Impact of total arterial #revascularization on long term #survival: A systematic review and meta-analysis of 130,305 patients

http://www.internationaljournalofcardiology.com/article/S0167-5273(17)30687-3/fulltext?rss=yes

Data from primarily observational studies suggest that TAR may improve long-term survival compared with conventional coronary bypass by 15–20% even when compared with two arterial grafts. Prospective randomized trials of TAR with long term follow-up are needed.

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Long term #survival, health, social functioning, and education in patients with European Lyme #neuroborreliosis: nationwide population based cohort study

https://www.bmj.com/content/361/bmj.k1998


Mortality among patients with Lyme neuroborreliosis was not higher than in the general population (mortality rate ratio 0.90, 95% confidence interval 0.79 to 1.03). Lyme neuroborreliosis patients had increased risk of haematological (incidence rate ratio 3.07, 2.03 to 4.66) and non-melanoma skin cancers (1.49, 1.18 to 1.88). At diagnosis, Lyme neuroborreliosis patients had slightly higher employment and lower disability pension rates. After five years, patients and comparison cohort members had similar numbers of hospital contacts (difference −0.22, 95% confidence interval −0.45 to 0.02, in-hospital days/year; 0.37, −0.10 to 0.83, outpatient visits/year), employment rates (difference 1.5%, −2.1% to 5.1%), income (difference −1000, −20 000 to 18 000, Danish kroner), days of sick leave (difference −0.3, −3.5 to 3.0, per year), rates of receipt of a disability pension (difference −0.9%, −3.2% to 1.3%), and number of children (difference –0.10, −0.27 to 0.08). More patients were married (difference 4.8%, 2.2% to 7.4%) and had completed high school education (difference 7%, 1% to 12%).

Conclusion A verified diagnosis of Lyme neuroborreliosis had no substantial effect on long term survival, health, or educational/social functioning. Nevertheless, the diagnosis decreased labour market involvement marginally and was associated with increased risk of haematological and non-melanoma skin cancers

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One-year #survival after in-hospital #cardiac arrest: a systematic review and meta-analysis

https://www.resuscitationjournal.com/article/S0300-9572(18)30850-5/fulltext?rss=yes&mobileUi=0

We included 40 studies in our systematic review and meta-analysis. The pooled one-year survival after in-hospital cardiac arrest was 13.4% (95%PI: 5.6-28.8%, I2 = 100%). Subgroup analysis of cardiac patients revealed a one-year survival of 39.3% (16.1%-68.6%) in patients with a non-cardiac admission characteristic one-year survival was 10.7% (4.4%-23.6%). These data cover the period 1985 – 2018 and show a modest change in survival over that period (10-year OR: 1.70, 95% CI: 1.04 – 2.76).

Discussion
One-year survival after in-hospital cardiac arrest is poor. Survival is higher in patients admitted to cardiac wards. The time trend between 1985-2018 has shown a modest improvement in one-year survival rates. Research into IHCA population characteristics might elicit the issue of heterogeneity and stagnated survival over the past decades.

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#Dog Ownership and #Survival
A Systematic Review and Meta-Analysis

Dog ownership has been associated with decreased cardiovascular risk. Recent reports have suggested an association of dog companionship with lower blood pressure levels, improved lipid profile, and diminished sympathetic responses to stress.

Dog ownership was associated with a 24% risk reduction for all-cause mortality as compared to nonownership (relative risk, 0.76; 95% CI, 0.67–0.86) with 6 studies demonstrating significant reduction in the risk of death. Notably, in individuals with prior coronary events, living in a home with a dog was associated with an even more pronounced risk reduction for all-cause mortality (relative risk, 0.35; 95% CI, 0.17–0.69; I2, 0%). Moreover, when we restricted the analyses to studies evaluating cardiovascular mortality, dog ownership conferred a 31% risk reduction for cardiovascular death (relative risk, 0.69; 95% CI, 0.67–0.71; I2, 5.1%).

Conclusions:
Dog ownership is associated with lower risk of death over the long term, which is possibly driven by a reduction in cardiovascular mortality

https://www.ahajournals.org/doi/10.1161/CIRCOUTCOMES.119.005554

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Associations between Serum Levels of #Cholesterol and #survival to Age 90 in Postmenopausal Women

Although elevated lipid levels predict increased risk of coronary heart disease and death in middle‐aged women and men, evidence is mixed if lipid levels measured in later life predict survival to very old ages..

HDL and LDL levels were not associated with survival to age 90 after adjustment for cardiovascular risk factors..

Similarly, no associations were observed between HDL and LDL levels and survival to age 90 with mobility disability. High HDL was not associated with survival to age 90 with intact mobility after adjustment for other cardiovascular risk factors. Compared with the lowest LDL quartile, the three upper LDL quartiles were associated with greater odds of survival to age 90 with intact mobility..

CONCLUSION
Neither higher HDL nor lower LDL levels predicted survival to age 90, but higher LDL predicted healthy survival. These findings suggest the need for reevaluation of healthy LDL levels in older women.

https://bit.ly/38hKHub

Association of Later-Life #Weight Changes With #Survival to Ages 90, 95, and 100: The Women’s Health Initiative

https://2medical.news/2023/09/07/association-of-later-life-weight-changes-with-survival-to-ages-90-95-and-100-the-womens-health-initiative/