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Aldo Lorenzetti M.D, Internal Medicine & Hepatology, Milano - SIMEDET Delegate
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Partial and Total #Sleep Deprivation Interferes with Neural Correlates of Consolidation of #Fear Extinction #Memory
https://2medical.news/2020/11/20/partial-and-total-sleep-deprivation-interferes-with-neural-correlates-of-consolidation-of-fear-extinction-memory/

We assessed the impact of total and partial sleep loss on neural correlates of fear conditioning and extinction learning and recall in healthy young adults. Methods Participants (56.3% female, age 24.8±3.4) were randomized to a night of normal sleep (NS, n=48), sleep restriction (SR, n=53), or sleep deprivation (SD, n=53). All completed fear conditioning and extinction learning phases the following morning. Extinction recall was tested …
Gut #microbiota depletion by chronic antibiotic treatment alters the #sleep/wake architecture and sleep #EEG power spectra in mice
https://2medical.news/2020/12/01/gut-microbiota-depletion-by-chronic-antibiotic-treatment-alters-the-sleep-wake-architecture-and-sleep-eeg-power-spectra-in-mice/

Dysbiosis of the gut microbiota affects physiological processes, including brain functions, by altering the intestinal metabolism. Here we examined the effects of the gut microbiota on sleep/wake regulation. C57BL/6 male mice were treated with broad-spectrum antibiotics for 4 weeks to deplete their gut microbiota. Metabolome profiling of cecal contents in antibiotic-induced microbiota-depleted (AIMD) and control mice showed significant variations in the metabolism of amino acids …
Assessment of Physician #Sleep and Wellness, #Burnout, and Clinically Significant Medical Errors
https://2medical.news/2020/12/11/assessment-of-physician-sleep-and-wellness-burnout-and-clinically-significant-medical-errors/

Sleep-related impairment in physicians is an occupational hazard associated with long and sometimes unpredictable work hours and may contribute to burnout and self-reported clinically significant medical error.. ..Of all physicians invited to participate in the survey, 7700 of 19 384 attending physicians (40%) and 3695 of 7257 house staff physicians (51%) completed sleep-related impairment items, including 5279 women (46%), 5187 men (46%), and 929 (8%) who …
Gut #microbiota depletion by chronic #antibiotic treatment alters the sleep/wake architecture and #sleep EEG power spectra in mice
https://2medical.news/2020/12/26/gut-microbiota-depletion-by-chronic-antibiotic-treatment-alters-the-sleep-wake-architecture-and-sleep-eeg-power-spectra-in-mice-2/

Dysbiosis of the gut microbiota affects physiological processes, including brain functions, by altering the intestinal metabolism. Here we examined the effects of the gut microbiota on sleep/wake regulation. C57BL/6 male mice were treated with broad-spectrum antibiotics for 4 weeks to deplete their gut microbiota. Metabolome profiling of cecal contents in antibiotic-induced microbiota-depleted (AIMD) and control mice showed significant variations in the metabolism of amino acids …
Association between self‐reported night #sleep duration and #cognitive function among older adults with intact global cognition
https://2medical.news/2021/04/09/association-between-self%E2%80%90reported-night-sleep-duration-and-cognitive-function-among-older-adults-with-intact-global-cognition/

The purpose of this study was to clarify the association between self‐reported night sleep duration and cognitive functions such as word memory, story memory, attention, executive function, and processing speed of older adults with normal global cognitive function. Methods A total of 241 functionally independent older adults (mean age, 75.5 ± 6.4 years) participated in this study. No participants had a history of dementia diagnosis, …