香港大學李嘉誠醫學院（港大醫學院）研究團隊透過現時首個以香港人為對象的最大型研究，在108個與藥物有關的基因中，發現：
1. 531個罕見且預測有害的基因變異，當中有96種未曾被記載於廣泛認受的資料庫之中。
2. 這些基因變異卻普遍存在於香港人身上，絕大部分人（93.6%）帶有最少一種與藥物有關的基因變異。
3. 幾乎所有（99.6%）香港人均帶有最少一種可能影響用藥效果的罕見基因變異。
In the first and largest study of its kind among Hong Kong Chinese, a research team at LKS Faculty of Medicine, The University of Hong Kong (HKUMed) has identified
1. 531 rare and predicted deleterious variants in 108 pharmacogenes, among which 96 have never been reported in widely recognised databases.
2. However, these variants were commonly found among Hong Kong Chinese, most of whom (93.6%) having at least one of them.
3. Besides, almost all (99.6%) Hong Kong Chinese residents harboured at least one actionable pharmacogenetic variant, which may impact the effectiveness of drug treatment.
Source：港大李嘉誠醫學院 https://is.gd/aErBZZ
#讀者投稿 #香港大學 #港大 #醫學院 #香港民族 #民族自強 #Hongkongers #HKU #research
1. 531個罕見且預測有害的基因變異，當中有96種未曾被記載於廣泛認受的資料庫之中。
2. 這些基因變異卻普遍存在於香港人身上，絕大部分人（93.6%）帶有最少一種與藥物有關的基因變異。
3. 幾乎所有（99.6%）香港人均帶有最少一種可能影響用藥效果的罕見基因變異。
In the first and largest study of its kind among Hong Kong Chinese, a research team at LKS Faculty of Medicine, The University of Hong Kong (HKUMed) has identified
1. 531 rare and predicted deleterious variants in 108 pharmacogenes, among which 96 have never been reported in widely recognised databases.
2. However, these variants were commonly found among Hong Kong Chinese, most of whom (93.6%) having at least one of them.
3. Besides, almost all (99.6%) Hong Kong Chinese residents harboured at least one actionable pharmacogenetic variant, which may impact the effectiveness of drug treatment.
Source：港大李嘉誠醫學院 https://is.gd/aErBZZ
#讀者投稿 #香港大學 #港大 #醫學院 #香港民族 #民族自強 #Hongkongers #HKU #research