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Aldo Lorenzetti M.D, Internal Medicine & Hepatology, Milano - SIMEDET Delegate
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Emotional #Stress Induces Structural Plasticity in Bergmann Glial Cells via an AC5–CPEB3–GluA1 Pathway
https://2medical.news/2020/05/01/emotional-stress-induces-structural-plasticity-in-bergmann-glial-cells-via-an-ac5-cpeb3-glua1-pathway-2/

..SIGNIFICANCE STATEMENT Astrocytes play important roles in synaptic transmission by extending fine processes around synapses. In this study, we showed that a single exposure to an acute stress triggered a retraction of lateral/fine processes in mouse cerebellar astrocytes. These astrocytes express GluA1, a glutamate receptor subunit known to lengthen astrocyte processes. We showed that astrocytic structural changes are associated with a reduction of GluA1 protein …
#Ageing attenuates the effect of extracellular hyperosmolality on whole‐body #heat exchange during exercise‐heat #stress
https://2medical.news/2020/10/14/ageing-attenuates-the-effect-of-extracellular-hyperosmolality-on-whole%E2%80%90body-heat-exchange-during-exercise%E2%80%90heat-stress/

Key points In humans, hypohydration attenuates sweat secretion and attenuates whole‐body heat loss, probably to mitigate further fluid losses and thereby support blood pressure regulation. Recently, however, we demonstrated that the hypohydration‐mediated reduction in net whole‐body heat exchange (evaporative heat loss – dry heat gain) was blunted in middle‐aged compared to younger men during moderate exercise in dry heat; albeit, the underpinning mechanisms could not …
The effects of acute #work #stress and appraisal on psychobiological stress responses in a group office environment
https://2medical.news/2020/11/08/the-effects-of-acute-work-stress-and-appraisal-on-psychobiological-stress-responses-in-a-group-office-environment/

The high prevalence of office stress and its detrimental health consequences are of concern to individuals, employers and society at large. Laboratory studies investigating office stress have mostly relied on data from participants that were tested individually on abstract tasks. In this study, we examined the effect of psychosocial office stress and work interruptions on the psychobiological stress response in a realistic but controlled group …
#Mediterranean diet, #stress resilience, and aging in nonhuman primates
https://2medical.news/2020/11/24/mediterranean-diet-stress-resilience-and-aging-in-nonhuman-primates/

Persistent psychological stress increases the risk of many chronic diseases of aging. Little progress has been made to effectively reduce stress responses or mitigate stress effects suggesting a need for better understanding of factors that influence stress responses. Limited evidence suggests that diet may be a factor in modifying the effects of stress. However, long-term studies of diet effects on stress reactive systems are not …
Effects of Stressful Events and Perceived #Stress on Cognitive Change Among #Depressed Older Adults
https://2medical.news/2021/03/21/effects-of-stressful-events-and-perceived-stress-on-cognitive-change-among-depressed-older-adults/

Stress is thought to exacerbate cognitive decline in older adults, especially those with late life depression (LLD); however, the specific aspects of stress that are especially deleterious and the aspects of cognition they affect are not clear. For example, it is not known whether the effects result from the exposure to stressful life events or whether it is the perception of stress that is salient, …
#Cocoa Flavanols Improve Vascular Responses to Acute Mental #Stress in Young Healthy Adults
https://2medical.news/2021/04/08/cocoa-flavanols-improve-vascular-responses-to-acute-mental-stress-in-young-healthy-adults/

Mental stress has been shown to induce cardiovascular events, likely due to its negative impact on vascular function. Flavanols, plant-derived polyphenolic compounds, improve endothelial function and blood pressure (BP) in humans, however their effects during stress are not known. This study examined the effects of acute intake of cocoa flavanols on stress-induced changes on vascular function. In a randomised, controlled, double-blind, cross-over intervention study, 30 …
Self-administered #mindfulness interventions reduce #stress in a large, randomized controlled multi-site study

https://2medical.news/?p=5334