Emotional #Stress Induces Structural Plasticity in Bergmann Glial Cells via an AC5–CPEB3–GluA1 Pathway
https://2medical.news/2020/05/01/emotional-stress-induces-structural-plasticity-in-bergmann-glial-cells-via-an-ac5-cpeb3-glua1-pathway-2/
..SIGNIFICANCE STATEMENT Astrocytes play important roles in synaptic transmission by extending fine processes around synapses. In this study, we showed that a single exposure to an acute stress triggered a retraction of lateral/fine processes in mouse cerebellar astrocytes. These astrocytes express GluA1, a glutamate receptor subunit known to lengthen astrocyte processes. We showed that astrocytic structural changes are associated with a reduction of GluA1 protein …
https://2medical.news/2020/05/01/emotional-stress-induces-structural-plasticity-in-bergmann-glial-cells-via-an-ac5-cpeb3-glua1-pathway-2/
..SIGNIFICANCE STATEMENT Astrocytes play important roles in synaptic transmission by extending fine processes around synapses. In this study, we showed that a single exposure to an acute stress triggered a retraction of lateral/fine processes in mouse cerebellar astrocytes. These astrocytes express GluA1, a glutamate receptor subunit known to lengthen astrocyte processes. We showed that astrocytic structural changes are associated with a reduction of GluA1 protein …
#Ageing attenuates the effect of extracellular hyperosmolality on whole‐body #heat exchange during exercise‐heat #stress
https://2medical.news/2020/10/14/ageing-attenuates-the-effect-of-extracellular-hyperosmolality-on-whole%E2%80%90body-heat-exchange-during-exercise%E2%80%90heat-stress/
Key points In humans, hypohydration attenuates sweat secretion and attenuates whole‐body heat loss, probably to mitigate further fluid losses and thereby support blood pressure regulation. Recently, however, we demonstrated that the hypohydration‐mediated reduction in net whole‐body heat exchange (evaporative heat loss – dry heat gain) was blunted in middle‐aged compared to younger men during moderate exercise in dry heat; albeit, the underpinning mechanisms could not …
https://2medical.news/2020/10/14/ageing-attenuates-the-effect-of-extracellular-hyperosmolality-on-whole%E2%80%90body-heat-exchange-during-exercise%E2%80%90heat-stress/
Key points In humans, hypohydration attenuates sweat secretion and attenuates whole‐body heat loss, probably to mitigate further fluid losses and thereby support blood pressure regulation. Recently, however, we demonstrated that the hypohydration‐mediated reduction in net whole‐body heat exchange (evaporative heat loss – dry heat gain) was blunted in middle‐aged compared to younger men during moderate exercise in dry heat; albeit, the underpinning mechanisms could not …
The effects of acute #work #stress and appraisal on psychobiological stress responses in a group office environment
https://2medical.news/2020/11/08/the-effects-of-acute-work-stress-and-appraisal-on-psychobiological-stress-responses-in-a-group-office-environment/
The high prevalence of office stress and its detrimental health consequences are of concern to individuals, employers and society at large. Laboratory studies investigating office stress have mostly relied on data from participants that were tested individually on abstract tasks. In this study, we examined the effect of psychosocial office stress and work interruptions on the psychobiological stress response in a realistic but controlled group …
https://2medical.news/2020/11/08/the-effects-of-acute-work-stress-and-appraisal-on-psychobiological-stress-responses-in-a-group-office-environment/
The high prevalence of office stress and its detrimental health consequences are of concern to individuals, employers and society at large. Laboratory studies investigating office stress have mostly relied on data from participants that were tested individually on abstract tasks. In this study, we examined the effect of psychosocial office stress and work interruptions on the psychobiological stress response in a realistic but controlled group …
#Mediterranean diet, #stress resilience, and aging in nonhuman primates
https://2medical.news/2020/11/24/mediterranean-diet-stress-resilience-and-aging-in-nonhuman-primates/
Persistent psychological stress increases the risk of many chronic diseases of aging. Little progress has been made to effectively reduce stress responses or mitigate stress effects suggesting a need for better understanding of factors that influence stress responses. Limited evidence suggests that diet may be a factor in modifying the effects of stress. However, long-term studies of diet effects on stress reactive systems are not …
https://2medical.news/2020/11/24/mediterranean-diet-stress-resilience-and-aging-in-nonhuman-primates/
Persistent psychological stress increases the risk of many chronic diseases of aging. Little progress has been made to effectively reduce stress responses or mitigate stress effects suggesting a need for better understanding of factors that influence stress responses. Limited evidence suggests that diet may be a factor in modifying the effects of stress. However, long-term studies of diet effects on stress reactive systems are not …
Effects of Stressful Events and Perceived #Stress on Cognitive Change Among #Depressed Older Adults
https://2medical.news/2021/03/21/effects-of-stressful-events-and-perceived-stress-on-cognitive-change-among-depressed-older-adults/
Stress is thought to exacerbate cognitive decline in older adults, especially those with late life depression (LLD); however, the specific aspects of stress that are especially deleterious and the aspects of cognition they affect are not clear. For example, it is not known whether the effects result from the exposure to stressful life events or whether it is the perception of stress that is salient, …
https://2medical.news/2021/03/21/effects-of-stressful-events-and-perceived-stress-on-cognitive-change-among-depressed-older-adults/
Stress is thought to exacerbate cognitive decline in older adults, especially those with late life depression (LLD); however, the specific aspects of stress that are especially deleterious and the aspects of cognition they affect are not clear. For example, it is not known whether the effects result from the exposure to stressful life events or whether it is the perception of stress that is salient, …
#Cocoa Flavanols Improve Vascular Responses to Acute Mental #Stress in Young Healthy Adults
https://2medical.news/2021/04/08/cocoa-flavanols-improve-vascular-responses-to-acute-mental-stress-in-young-healthy-adults/
Mental stress has been shown to induce cardiovascular events, likely due to its negative impact on vascular function. Flavanols, plant-derived polyphenolic compounds, improve endothelial function and blood pressure (BP) in humans, however their effects during stress are not known. This study examined the effects of acute intake of cocoa flavanols on stress-induced changes on vascular function. In a randomised, controlled, double-blind, cross-over intervention study, 30 …
https://2medical.news/2021/04/08/cocoa-flavanols-improve-vascular-responses-to-acute-mental-stress-in-young-healthy-adults/
Mental stress has been shown to induce cardiovascular events, likely due to its negative impact on vascular function. Flavanols, plant-derived polyphenolic compounds, improve endothelial function and blood pressure (BP) in humans, however their effects during stress are not known. This study examined the effects of acute intake of cocoa flavanols on stress-induced changes on vascular function. In a randomised, controlled, double-blind, cross-over intervention study, 30 …
Selective serotonin reuptake inhibitors, and serotonin and norepinephrine reuptake inhibitors for #anxiety, #obsessive-compulsive, and #stress disorders: A 3-level network meta-analysis
https://2medical.news/2021/06/12/selective-serotonin-reuptake-inhibitors-and-serotonin-and-norepinephrine-reuptake-inhibitors-for-anxiety-obsessive-compulsive-and-stress-disorders-a-3-level-network-meta-analysis/
https://2medical.news/2021/06/12/selective-serotonin-reuptake-inhibitors-and-serotonin-and-norepinephrine-reuptake-inhibitors-for-anxiety-obsessive-compulsive-and-stress-disorders-a-3-level-network-meta-analysis/
2Medical.News
Selective serotonin reuptake inhibitors, and serotonin and norepinephrine reuptake inhibitors for #anxiety, #obsessive-compulsive…
Anxiety, obsessive-compulsive, and stress-related disorders frequently co-occur, and patients often present symptoms of several domains. Treatment involves the use of selective serotonin reuptake i…
Reduced adaptation of glutamatergic #stress response is associated with #pessimistic expectations in #depression
https://2medical.news/2021/06/17/reduced-adaptation-of-glutamatergic-stress-response-is-associated-with-pessimistic-expectations-in-depression/
https://2medical.news/2021/06/17/reduced-adaptation-of-glutamatergic-stress-response-is-associated-with-pessimistic-expectations-in-depression/
2Medical.News
Reduced adaptation of glutamatergic #stress response is associated with #pessimistic expectations in #depression
Stress is a significant risk factor for the development of major depressive disorder (MDD), yet the underlying mechanisms remain unclear. Preclinically, adaptive and maladaptive stress-induced chan…
#Mineralocorticoid receptors dampen glucocorticoid receptor sensitivity to #stress via regulation of FKBP5
https://2medical.news/2021/06/20/mineralocorticoid-receptors-dampen-glucocorticoid-receptor-sensitivity-to-stress-via-regulation-of-fkbp5/
https://2medical.news/2021/06/20/mineralocorticoid-receptors-dampen-glucocorticoid-receptor-sensitivity-to-stress-via-regulation-of-fkbp5/
2Medical.News
#Mineralocorticoid receptors dampen glucocorticoid receptor sensitivity to #stress via regulation of FKBP5
Responding to different dynamic levels of stress is critical for mammalian survival. Disruption of mineralocorticoid receptor (MR) and glucocorticoid receptor (GR) signaling is proposed to underlie…
Urinary #Stress Hormones, #Hypertension, and Cardiovascular Events: The Multi-Ethnic Study of Atherosclerosis
https://2medical.news/2021/09/19/urinary-stress-hormones-hypertension-and-cardiovascular-events-the-multi-ethnic-study-of-atherosclerosis/
https://2medical.news/2021/09/19/urinary-stress-hormones-hypertension-and-cardiovascular-events-the-multi-ethnic-study-of-atherosclerosis/
2Medical.News
Urinary #Stress Hormones, #Hypertension, and Cardiovascular Events: The Multi-Ethnic Study of Atherosclerosis
Psychosocial stress is a key contributing factor to the pathogenesis of hypertension and cardiovascular disease. We examined the association of urinary stress hormone levels with incident hypertens…
The psychophysiology of Mastermind: Characterizing response times and #blinking in a high-stakes television game show
https://2medical.news/2023/11/18/the-psychophysiology-of-mastermind-characterizing-response-times-and-blinking-in-a-high-stakes-television-game-show/
https://2medical.news/2023/11/18/the-psychophysiology-of-mastermind-characterizing-response-times-and-blinking-in-a-high-stakes-television-game-show/
2Medical.News
The psychophysiology of Mastermind: Characterizing response times and #blinking in a high-stakes television game show
Television game shows have proven to be a valuable resource for studying human behavior under conditions of high #stress and high stakes. However, previous work has focused mostly on choices—ignori…
Association Between Electronic Diary–Rated #Sleep, Mood, Energy, and #Stress With Incident #Headache in a Community-Based Sample
https://2medical.news/2024/02/06/association-between-electronic-diary-rated-sleep-mood-energy-and-stress-with-incident-headache-in-a-community-based-sample/
https://2medical.news/2024/02/06/association-between-electronic-diary-rated-sleep-mood-energy-and-stress-with-incident-headache-in-a-community-based-sample/
2Medical.News
Association Between Electronic Diary–Rated #Sleep, Mood, Energy, and #Stress With Incident #Headache in a Community-Based Sample
The aim of this study was to examine the diurnal links between average and changes in average levels of prospectively rated mood, sleep, energy, and stress as predictors of incident headache in a c…
Self-administered #mindfulness interventions reduce #stress in a large, randomized controlled multi-site study
https://2medical.news/?p=5334
https://2medical.news/?p=5334
Posttraumatic #Stress Disorder and Obstructive Sleep #Apnea in Twins
https://2medical.news/2024/07/12/posttraumatic-stress-disorder-and-obstructive-sleep-apnea-in-twins/
https://2medical.news/2024/07/12/posttraumatic-stress-disorder-and-obstructive-sleep-apnea-in-twins/
2Medical.News
Posttraumatic #Stress Disorder and Obstructive Sleep #Apnea in Twins
Key PointsQuestion What is the association of posttraumatic stress disorder (PTSD) with obstructive sleep apnea (OSA) after accounting for acknowledged medical risk factors for OSA?Findings In a …
#Stress -resilience impacts psychological wellbeing as evidenced by brain–gut #microbiome interactions
https://2medical.news/2024/07/13/stress-resilience-impacts-psychological-wellbeing-as-evidenced-by-brain-gut-microbiome-interactions/
https://2medical.news/2024/07/13/stress-resilience-impacts-psychological-wellbeing-as-evidenced-by-brain-gut-microbiome-interactions/
2Medical.News
#Stress -resilience impacts psychological wellbeing as evidenced by brain–gut #microbiome interactions
The brain–gut microbiome (BGM) system plays an influential role on mental health. We characterized BGM patterns related to resilience using fecal samples and multimodal magnetic resonance imaging. …