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Aldo Lorenzetti M.D, Internal Medicine & Hepatology, Milano - SIMEDET Delegate
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#Colorectal Cancer Risk Following #Bariatric Surgery in a Nationwide Study of French Individuals With Obesity
https://2medical.news/2020/03/18/colorectal-cancer-risk-following-bariatric-surgery-in-a-nationwide-study-of-french-individuals-with-obesity/

..The mean (SD) follow-up was 6.2 (2.1) years for patients who underwent adjustable gastric banding, 5.5 (2.1) years for patients who underwent sleeve gastrectomy, and 5.7 (2.2) years for patients who underwent gastric bypass. In total, 13 052 incident colorectal cancers (1.2%) and 63 649 colorectal benign polyps were diagnosed. The rate of colorectal cancer was 0.6% in the bariatric surgery cohort and 1.3% in the cohort …
#ACE (Angiotensin-Converting Enzyme) Inhibitors/Angiotensin Receptor Blockers Are Associated With Lower #Colorectal Cancer Risk
https://2medical.news/2020/07/11/ace-angiotensin-converting-enzyme-inhibitors-angiotensin-receptor-blockers-are-associated-with-lower-colorectal-cancer-risk/

Whether ACE (angiotensin-converting enzyme) inhibitors and angiotensin receptor blockers modify colorectal cancer risk remains controversial. We aimed to determine association between their use and colorectal cancer risk after a negative baseline colonoscopy. This is a territory-wide retrospective cohort study recruiting patients aged ≥40 who had undergone colonoscopy between 2005 and 2013. Exclusion criteria included colorectal cancer detected <6 months of index colonoscopy, prior colorectal cancer, …
Association of #Coffee Intake With Survival in Patients With Advanced or Metastatic #Colorectal Cancer
https://2medical.news/2020/09/21/association-of-coffee-intake-with-survival-in-patients-with-advanced-or-metastatic-colorectal-cancer/

Several compounds found in coffee possess antioxidant, anti-inflammatory, and insulin-sensitizing effects, which may contribute to anticancer activity. Epidemiological studies have identified associations between increased coffee consumption and decreased recurrence and mortality of colorectal cancer. The association between coffee consumption and survival in patients with advanced or metastatic colorectal cancer is unknown.. ..Among the 1171 patients included in the analysis (694 men [59%]; median age, 59 …
ACG Clinical Guidelines: #Colorectal #Cancer Screening 2021
https://2medical.news/2021/03/12/acg-clinical-guidelines-colorectal-cancer-screening-2021/

1. We recommend CRC screening in average-risk individuals between ages 50 and 75 years to reduce incidence of advanced adenoma, CRC, and mortality from CRC. Strong recommendation; moderate-quality evidence 2. We suggest CRC screening in average-risk individuals between ages 45 and 49 years to reduce incidence of advanced adenoma, CRC, and mortality from CRC. Conditional recommendation; very low-quality evidence 3. We suggest that a decision …