Long-Term Survival Among Patients With Myocardial #Infarction Before #Age 50 Compared With the General Population

http://m.circoutcomes.ahajournals.org/content/early/2016/08/30/CIRCOUTCOMES.115.002661

Conclusions—The long-term mortality rate after MI before age 50 has decreased remarkably over the last 3 decades, but remains increased relative to the general population, mainly because of deaths from ischemic heart disease and other smoking-related diseases.

#DNA methylation-based measures of biological #age: meta-analysis predicting time to death

http://www.aging-us.com/article/a4YqjiSauBRXHwfiX/text

Overall, this study a) strengthens the evidence that epigenetic age predicts all-cause mortality above and beyond chronological age and traditional risk factors, and b) demonstrates that epigenetic age estimates that incorporate information on blood cell counts lead to highly significant associations with all-cause mortality.

Online self-assessment of #cardiovascular risk using the Joint British Societies (JBS3)-derived heart #age tool: a descriptive study

http://bmjopenbeta.bmj.com/content/6/9/e011511.full

Conclusions These data suggest a high level of public interest in self-assessment of cardiovascular risk when an easily understood metric is used, although a large number of users lack awareness of their own risk factors.

Physician #age and outcomes in #elderly patients in hospital in the US: observational study
http://www.bmj.com/content/357/bmj.j1797

Objectives To investigate whether outcomes of patients who were admitted to hospital differ between those treated by younger and older physicians.

Conclusions Within the same hospital, patients treated by older physicians had higher mortality than patients cared for by younger physicians, except those physicians treating high volumes of patients.

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Association of #Age With Blood #Pressure Across the Lifespan in Isolated Yanomami and Yekwana Villages

https://jamanetwork.com/journals/jamacardiology/article-abstract/2713959

A dogma of cardiology is that blood pressure (BP) increases with age.1,2 Yet studies of non-Westernized adults from isolated hunter-gatherer peoples have found little evidence of an age-associated rise in BP.3 To date, no studies have recorded BP in children of isolated communities and examined the age-BP association over the entire lifespan, and no studies have compared age-BP association in geographically colocated communities with different levels of Westernization.

To put our findings into context, in the United States, [systolic] BP increases by approximately 1.5 mm Hg per year among girls, approximately 1.9 mm Hg per year among boys, and approximately 0.6 mm Hg per year in adults. Although our study is cross-sectional and limited by small sample size, it adds to findings in Yanomami adults showing the rise in BP with age may not be natural but rather a consequence of unnatural Western exposures,” Mueller and colleagues wrote. – by Earl Holland

#Fasting-mimicking #diet causes hepatic and blood markers changes indicating reduced biological #age and disease risk

https://2medical.news/2024/02/22/fasting-mimicking-diet-causes-hepatic-and-blood-markers-changes-indicating-reduced-biological-age-and-disease-risk/