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Тоді швидше реєструйся на наш новий захід: лекція від чарівної Світлани Антоненко - кандидатки біологічних наук, наукової співробітниці Інституту молекулярної біології і генетики НАН України, лекторки в МАН для педагогів (курси підвищення кваліфікації) і курси для дітей, педагог з підготовки учнів до участі в міжнародних олімпіадах.

Дата: 21.06; 17.00

Тема: "Молекулярно-генетичні механізми розвитку хронічної мієлоїдної лейкемії та підходи до терапії захворювання".

Не проґав свою можливість дізнатися щось нове!

#лекції

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The Science Behind Deja Vu: Exploring the Neurophysiology of Familiarity

"That was our place, I found it first

I made the jokes you tell to her when she's with you…

Do you get déjà vu when she's with you?

Do you get déjà vu, huh?"

Well-well, buddy, our today’s post has started quite differently from most of them before thanks to the beautiful song of Olivia Rodrigo, and I should already ask you: "Did you find all this situation pretty familiar?". I mean, the name of the article, these lines from the song, your body position on a sofa or a chair... Does something make you feel like you were actually in a particularly similar situation before? It doesn’t matter if you have this sensation or not at the moment, but you definitely had it in the past. Let me introduce this shrouded-in-mystery neurophysiological process: that’s deja vu, my clever reader, and today I am going to deepen your knowledge of the peculiarities of the appearance of this feelingand the possible causes of its occurrence from the point of view of physiology.

How does it occur? The exact order of processes is pretty hard to investigate and recreate, but despite it, I’ve found newsworthy information on how the common sensation of deja vu forms. Deja vu, a feeling of having experienced something before, could be caused by a small malfunction in the brain's pathways that transmit sensory information to higher processing centres. Different pathways carry incoming sensory data, and a neurochemical event that affects the speed of transmission in one pathway only (such as a momentary depletion of neurotransmitters at a neuronal connection) could create the illusion of deja vu. This is because the brain combines information from different pathways to create a unified experience, and a slight delay or acceleration in one pathway relative to another could make the brain interpret the data as separate copies of the same practice. A similar explanation involves communication between the brain's two hemispheres. If incoming information travels directly to the dominant hemisphere for processing but also goes through the non-dominant hemisphere before reaching the dominant hemisphere, a delay in the fibres that transmit information between the hemispheres (through the corpus callosum) could also result in deja vu.

Actually, I hunted up the two gripping medical case reports, one of Darrin J Lee and another of Norbert Kovacs, that were written in 2009 to reveal this issue from the perspective of pathologies. Darrin reported a case where a teenager had seizures, deja vu, and olfactory auras that were resolved after an amygdalectomy. This demonstrated that the amygdala alone can cause these types of auras without involvement from other parts of the mesial temporal lobe. Kovacs provided a detailed account of treating hemidystonia using deep brain stimulation (DBS) to the globus pallidus. They noticed that DBS-induced deja vu was associated with increased blood flow in the right hemisphere mesial temporal structures, which they confirmed through imaging. Both reports suggest that the mesial temporal regions are involved in generating deja vu.

The early fascination with deja vu was due to the observation that individuals with temporal lobe epilepsy experienced it as part of their pre-seizure aura. Does it mean that rapid feelings of deja vu indicate temporal lobe epilepsy and cannot occur in completely healthy people? As might be expected, a frequent occurrence (more than 1-2 times per year) of such sensations may be caused by taking drugs, sudden seizure activity, stress, or migraines.

Well, it seems to be pretty comprehensible now; therefore, only one question remains to be answered: "How many times did you get deja vu last year?" 😏

Джерела

Авторка: @ast_jor

Дизайнерка: @velass

#engфаза

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https://us04web.zoom.us/j/72676335214?pwd=LKDR7fZfPPbR3qQQP3FttUx2yB1EY7.1