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Канал о процессе подготовки к экзаменам по USMLE, да и просто о медицине🧑🏻‍⚕️
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A 2-month-old boy is brought to the emergency department by his mother because of an 8-hour history of difficulty feeding and decreased arousability. His mother says that the symptoms began after he rolled over and fell from the bed. His vital signs are within normal limits. Examination shows regions of purple discoloration in the T4–T10 dermatomes bilaterally and tense fontanelles. Fundoscopy shows bilateral optic disc swelling with dot-and-blot hemorrhages extending to the ora serrata. Which of the following is the most likely diagnosis?
A 43-year-old man is brought to the physician for a follow-up examination. He has a history of epilepsy that has been treated with a stable dose of phenytoin for 15 years. He recently sought treatment for an unrelated condition by another physician who prescribed him a new medication, but he cannot recall its name. Shortly after, he started noticing occasional double vision. Physical examination shows slight vertical nystagmus and gait ataxia. The physician suspects phenytoin toxicity. Which of the following drugs was most likely added to this patient's medication regimen by the previous physician?
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A 64-year-old man is brought to the emergency department because of dull lower abdominal pain for 3 hours. He has not urinated for 24 hours and has not passed stool for over 3 days. He was diagnosed with herpes zoster 4 weeks ago and continues to have pain even after his rash resolved. He has hypertension, benign prostatic hyperplasia, and coronary artery disease. Physical examination shows a tender, palpable suprapubic mass. Bowel sounds are hypoactive. Abdominal ultrasound shows a large anechoic mass in the pelvis. Which of the following drugs most likely accounts for this patient's current symptoms?
A 27-year-old woman comes to the physician because of a 1-year history of progressive shortness of breath. She is now unable to jog for more than 10 minutes without stopping to catch her breath. Cardiac examination shows a harsh systolic, crescendo-decrescendo murmur best heard at the lower left sternal border. The murmur increases in intensity when she moves from a squatting to a standing position and decreases when she clenches her fists. The lungs are clear to auscultation. Which of the following is the most likely cause of her condition?
Severe pneumonia + GI symptoms + CNS symptoms + Hyponatremia. Diagnosis?
Угадайте по картинке про какую бактерию идет речь? 🔥
A 54-year-old man comes to the emergency department because of a 3-week history of intermittent swelling of his left arm and feeling of fullness in his head that is exacerbated by lying down and bending over to tie his shoes. Physical examination shows left-sided facial edema and distention of superficial veins in the neck and left chest wall. Which of the following is the most likely cause of this patient's symptoms?
A 73-year-old man is brought to the emergency department because of fever, malaise, dyspnea, and a productive cough with purulent sputum for the past day. His temperature is 39.2°C (102.6°F). Pulmonary examination shows crackles over the right upper lung field. Sputum Gram stain shows gram-positive cocci. Despite the appropriate treatment, the patient dies 5 days later. At autopsy, gross examination shows that the right lung has a pale, grayish-brown appearance and a firm consistency. Microscopic examination of the tissue is most likely to show which of the following?
A 45-year-old man with a 5-year history of worsening shortness of breath and cough comes to the physician for a follow-up examination. He has never smoked. His pulse is 75/min, blood pressure is 130/65 mm Hg, and respirations are 25/min. Examination shows an increased anteroposterior diameter of the chest. Diminished breath sounds and wheezing are heard on auscultation of the chest. An x-ray of the chest shows widened intercostal spaces, a flattened diaphragm, and basilar-predominant bullous changes of the lungs. This patient is at increased risk for which of the following complications?
An 8-day-old boy is being evaluated in the neonatal intensive care unit.  The patient was born at 27 weeks gestation and intubated at birth due to surfactant deficiency.  Temperature is 37 C (98.6 F), blood pressure is 66/12 mm Hg, and pulse is 182/min.  A continuous harsh murmur is heard at the left infraclavicular region.  There are bounding femoral and palmar pulses.  A drug with which of the following mechanisms of action is most appropriate for treating the cause of this patient's murmur?​‌​‌​‌​​‌‌​‌‌‌​‌‌​​‌​‌‌​‌​​​​​‌​​‌​‌‌​‌​​‌‌​‌​‌‌​‌​‌‌​‌​‌‌​​​​​‌‌​‌‌‌‌​​‌​​‌​​‌​‌​‌‌​​‌‌​‌​​‌‌​​‌‌‌‌‌‌‌‌‌‌​‌‌‌‌​‌​​​​‌​​‌​​‌‌​‌‌‌​‌​‌​​‌​​‌​‌‌​​​​​​‌‌‌​​​‌‌‌​​‌​​‌‌​‌​‌‌‌‌‌​​​‌‌‌‌​‌‌​‌‌​‌​‌‌‌​​​​‌‌​‌​‌‌​​‌​‌​​‌‌‌​​​‌‌​​‌‌​​​‌‌​​​​‌​‌‌‌‌‌​‌​​‌​‌‌​‌‌​​‌‌‌‌​‌​‌‌​‌‌​​‌​​​‌​​​​​‌‌‌​​‌​‌‌‌‌‌​​​‌​​‌​‌​​​‌‌​‌​​‌​‌‌‌‌‌​‌‌‌‌​‌​​​‌‌‌​‌​​​‌‌​

A. Activation of phospholipase A2​‌​‌​‌​​‌‌​‌‌‌​‌‌​​‌​‌‌​‌​​​​​‌​​‌​‌‌​‌​​‌‌​‌​‌‌​‌​‌‌​‌​‌‌​​​​​‌‌​‌‌‌‌​​‌​​‌​​‌​‌​‌‌​​‌‌​‌​​‌‌​​‌‌‌‌‌‌‌‌‌‌​‌‌‌‌​‌​​​​‌​​‌​​‌‌​‌‌‌​‌​‌​​‌​​‌​‌‌​​​​​​‌‌‌​​​‌‌‌​​‌​​‌‌​‌​‌‌‌‌‌​​​‌‌‌‌​‌‌​‌‌​‌​‌‌‌​​​​‌‌​‌​‌‌​​‌​‌​​‌‌‌​​​‌‌​​‌‌​​​‌‌​​​​‌​‌‌‌‌‌​‌​​‌​‌‌​‌‌​​‌‌‌‌​‌​‌‌​‌‌​​‌​​​‌​​​​​‌‌‌​​‌​‌‌‌‌‌​​​‌​​‌​‌​​​‌‌​‌​​‌​‌‌‌‌‌​‌‌‌‌​‌​​​‌‌‌​‌​​​‌‌​
B. Activation of prostacyclin receptors
C. Activation of prostaglandin E2​‌​‌​‌​​‌‌​‌‌‌​‌‌​​‌​‌‌​‌​​​​​‌​​‌​‌‌​‌​​‌‌​‌​‌‌​‌​‌‌​‌​‌‌​​​​​‌‌​‌‌‌‌​​‌​​‌​​‌​‌​‌‌​​‌‌​‌​​‌‌​​‌‌‌‌‌‌‌‌‌‌​‌‌‌‌​‌​​​​‌​​‌​​‌‌​‌‌‌​‌​‌​​‌​​‌​‌‌​​​​​​‌‌‌​​​‌‌‌​​‌​​‌‌​‌​‌‌‌‌‌​​​‌‌‌‌​‌‌​‌‌​‌​‌‌‌​​​​‌‌​‌​‌‌​​‌​‌​​‌‌‌​​​‌‌​​‌‌​​​‌‌​​​​‌​‌‌‌‌‌​‌​​‌​‌‌​‌‌​​‌‌‌‌​‌​‌‌​‌‌​​‌​​​‌​​​​​‌‌‌​​‌​‌‌‌‌‌​​​‌​​‌​‌​​​‌‌​‌​​‌​‌‌‌‌‌​‌‌‌‌​‌​​​‌‌‌​‌​​​‌‌​ receptors
D. Inhibition of cyclooxygenase
E. Inhibition of lipoxygenase
F. Inhibition of prostaglandin D2​‌​‌​‌​​‌‌​‌‌‌​‌‌​​‌​‌‌​‌​​​​​‌​​‌​‌‌​‌​​‌‌​‌​‌‌​‌​‌‌​‌​‌‌​​​​​‌‌​‌‌‌‌​​‌​​‌​​‌​‌​‌‌​​‌‌​‌​​‌‌​​‌‌‌‌‌‌‌‌‌‌​‌‌‌‌​‌​​​​‌​​‌​​‌‌​‌‌‌​‌​‌​​‌​​‌​‌‌​​​​​​‌‌‌​​​‌‌‌​​‌​​‌‌​‌​‌‌‌‌‌​​​‌‌‌‌​‌‌​‌‌​‌​‌‌‌​​​​‌‌​‌​‌‌​​‌​‌​​‌‌‌​​​‌‌​​‌‌​​​‌‌​​​​‌​‌‌‌‌‌​‌​​‌​‌‌​‌‌​​‌‌‌‌​‌​‌‌​‌‌​​‌​​​‌​​​​​‌‌‌​​‌​‌‌‌‌‌​​​‌​​‌​‌​​​‌‌​‌​​‌​‌‌‌‌‌​‌‌‌‌​‌​​​‌‌‌​‌​​​‌‌​ receptors
Интересная задача на внимательность🧠