Health Research Stories
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We share inside stories from high-quality and impactful health research. Validate the evidence: https://zheln.com
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Channel name was changed to «Zheln Health Evidence»
Channel name was changed to «Evidence-based Health News»
Channel name was changed to «Health News & Evidence»
Channel name was changed to «Health Research Stories»
How can doctors know which cancer treatment is better? One way is by riding slugs.

Learn how and pick the best cancer treatment option based on bleeding-edge scientific evidence from human trials: https://zheln.com/thread/2024/01/11/1/

If you feel critical about this post, we invite you to review its video bibliography, captured with @WriteInStonePublic, and drop any criticisms in the comments. Pavel Zhelnov, MD, will address all valid concerns and acknowledge the peer reviewers in the following Zheln post. We look forward to reading your messages.
Tamiflu is a widely advertised anti-flu drug that failed to show dramatic effects in clinical trials. Powered by @WriteInStonePublic, we revisit the evidence in light of a major 2023 meta-analysis and argue why highlighing failures might be as important as distilling benefits.
Seatbelt promotion works, but how well? 60% of drivers still don’t use seat belts, and even more passengers. Tracking steps with @WriteInStonePublic software, we discuss a recent systematic review that looked at the effectiveness of seat-belt promotion more closely.
Gentle human touch was shown to reduce pain in newborn babies. A new systematic review found that neonates do suffer from airway suctioning, but careful positioning likely alleviates pain. How did researchers measure it? Follow our steps using @WriteInStonePublic in a new Zheln post.
Zheln’s (impolite) take on hazard vs. risk and some pieces of health research – and their authoritative academic publishers – that still fail to use a comprehensive search strategy in a systematic review and overlook the existence of ROBINS-E in 2024: https://hey.xyz/posts/0x04fcbd-0x09-DA-2c9ba1a1
Dipeptidyl peptidase-4 (DPP4) inhibitors do not work.

The market share is US$ 11.6 billion.

They are not effective at all, with high certainty.

DPP4 inhibitors are one of the newer drugs people with type 2 diabetes use to lower their blood sugar levels. They include medications such as Januvia (sitagliptin), Onglyza (saxagliptin), Tradjenta (linagliptin), Nesina or Vipidia (alogliptin), and Galvus (vildagliptin).

Objections?

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Probiotics won’t make you poop, but lactulose will, with moderate certainty.

Taking lactulose for an average of 4 weeks leads to at least one more additional stool per week in adults with positive Rome criteria for constipation.

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Can Universal Basic Income solve the problem of poverty? *

According to statistics, low income levels are associated with higher mortality rates and worse outcomes in the treatment of chronic diseases. Moreover, a report by the World Bank and World Health Organization shows that high healthcare costs push many people to the brink of poverty, forcing them to choose between buying food and paying for medical services.

To address this issue, the idea of introducing Universal Basic Income (UBI)—an untouchable sum granted to every member of society—has been discussed for many years. However, critics are skeptical of UBI, citing a lack of evidence on the strategic effectiveness of such a solution.

A new study published in the Campbell Systematic Reviews database sheds light on this issue. The authors conducted a meta-analysis to evaluate the impact of various forms of UBI on poverty-related indicators.