Zheln has proudly been accepted as an Evidence Ambassador for #WorldEBHCday 2021, so I would like to acknowledge and comment on this as well as cover the #infodemic in this special supplement. Also, some news about the future of #Zheln have been accumulating, so I am using this opportunity to share them. https://zheln.com/summary/2021/10/20/suppl/

I announce discontinuation of Zheln in its original form and announce the new concept of Zheln As Service that, hopefully, will allow me to reuse the principal method for Zheln in other initiatives. https://zheln.com/summary/2022/04/06/suppl/

It’s been two years since I started working on my Reproducible Systematic Subset query for #PubMed to power my knowledge synthesis appraisals at zheln.com, and look what I have found so far ⬇
https://threadreaderapp.com/thread/1591261954349625345.html

When someone asks me what I do, and I reply with something like ‘I’m an evidence synthesis researcher,’ they are usually having a hard time understanding that. It need not be this way. In fact, knowledge synthesis is something everybody does every day of their lives. [Thread] 👇 https://threadreaderapp.com/thread/1617772138529959938.html

Why are we still looking through guidelines to get a clinical answer? Naturally, we need a chatbot that was trained on these guidelines so we can simply ask⚡️ [Thread] 👇 https://threadreaderapp.com/thread/1625440702640406528.html

Eight months ago, an important study was out, with its results relevant for 200 million people, but went largerly unnoticed. Wut? Zheln finds out👇 Thread #1

The International Olympic Committee recognized beetroot as a potent performance booster, among other nitrate supplements. Everybody else claims beetroot is “powerful” stuff to take before exercise. Is it? Zheln collected and appraised current research using @WriteInStonePublic and found no ground for such optimism, even though there are data from dozens of trials that might come useful in specific contexts. Watch popular internet claims smash against evidence: https://zheln.com/thread/2023/12/28/1/

No evidence cranberry juice is helpful for urinary infections in pregnancy, multiple studies find.

There is a mild preventative effect among children and non-pregnant women with recurrent UTIs ­– but those findings are still provisional. Learn the evidence feat. a @WriteInStonePublic video bibliography.

How can doctors know which cancer treatment is better? One way is by riding slugs.

Learn how and pick the best cancer treatment option based on bleeding-edge scientific evidence from human trials: https://zheln.com/thread/2024/01/11/1/

If you feel critical about this post, we invite you to review its video bibliography, captured with @WriteInStonePublic, and drop any criticisms in the comments. Pavel Zhelnov, MD, will address all valid concerns and acknowledge the peer reviewers in the following Zheln post. We look forward to reading your messages.

Tamiflu is a widely advertised anti-flu drug that failed to show dramatic effects in clinical trials. Powered by @WriteInStonePublic, we revisit the evidence in light of a major 2023 meta-analysis and argue why highlighing failures might be as important as distilling benefits.

Seatbelt promotion works, but how well? 60% of drivers still don’t use seat belts, and even more passengers. Tracking steps with @WriteInStonePublic software, we discuss a recent systematic review that looked at the effectiveness of seat-belt promotion more closely.

Gentle human touch was shown to reduce pain in newborn babies. A new systematic review found that neonates do suffer from airway suctioning, but careful positioning likely alleviates pain. How did researchers measure it? Follow our steps using @WriteInStonePublic in a new Zheln post.

Zheln went #SocialFi, and here is a short post on opioid use disorder: https://hey.xyz/posts/0x04fcbd-0x05

What evidence do we have of the association between fluoride exposure and thyroid function? Check this funny summary of findings table: https://hey.xyz/posts/0x04fcbd-0x08-DA-a7d09302

Zheln’s (impolite) take on hazard vs. risk and some pieces of health research – and their authoritative academic publishers – that still fail to use a comprehensive search strategy in a systematic review and overlook the existence of ROBINS-E in 2024: https://hey.xyz/posts/0x04fcbd-0x09-DA-2c9ba1a1