I am talking to a patron saint of female hysteria and its fun 😁

Magnesium sits inside the NMDA receptor channel as a voltage-dependent block. At resting membrane potential, Mg2+ physically occludes the pore and prevents calcium from entering the neuron. The neuron only fires when properly depolarized: glutamate binding plus sufficient voltage displacement of the Mg2+ plug.

When systemic magnesium is low, that block weakens. The threshold for neuronal firing drops. Neurons become hyperexcitable, not because something is stimulating them, but because the gate that normally keeps them quiet isn't holding. This is why magnesium deficiency presents as anxiety, insomnia, and sensory irritability before anything shows up on a standard blood panel. Serum Mg reflects less than 1% of total body stores and is actively defended by renal and bone resorption, so it stays "normal" long after tissue levels have dropped.

About half of US adults don't meet the RDA for magnesium (310-420 mg/day depending on age and sex), based on NHANES intake data. The mechanism described here, voltage-dependent NMDA channel block, was characterized by Mayer et al. and Nowak et al. in 1984 and is one of the best-established ion channel interactions in neuroscience.

Sources: Mayer et al., Nature, 1984. Nowak et al., Nature, 1984. Rosanoff et al., Nutr Rev, 2012.

Man the way i am feeling homesick 😅

I am watching youtube videos and tiktok videos of my city 🥹

My devotion to teaching

Yeah pollution

They are gonna dance on my bed.

Arsenal won 🥲

There’s a kind of intelligence that doesn’t feel like
“knowing more,” but like noticing more precisely

At first, everything looks like separate facts symptoms, concepts, arguments, names. But over time, you start seeing the hidden continuity underneath them. The way physiology becomes pathology under stress. The way philosophy becomes psychology when applied to people. The way nothing really stays in its own box.

That’s where thinking gets interesting: when categories stop behaving like walls and start behaving like lenses.


And the strange thing is, the more refined your thinking becomes, the less satisfying quick certainty feels. You start preferring accurate confusion over comfortable conclusions.

So the work quietly shifts. Not toward “figuring everything out,” but toward learning how to think without collapsing complexity into simplicity too early 🩺📚

-Notes from the wards.

Influenced from a talk I had with an internal medicine senior.

He was telling me bout the approach and the lenses every student, residents, senior approach to a minor signs or symptoms and stuff.

Basically bout webinars.

Ellll Magnificoooooooooooooo

will stop writing here.

Archived till we return some day]

Weyala wancha libela ?


Egir yblaaaaaaa

Selamawi summer window

Selamawi world cup