Good morning ☕ Here are today's papers!
Preprints:👇
No preprints found today.
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Papers:👇
🗞️ Inferring stochastic dynamics by biophysical Neural ODE using single-cell transcriptomics.
🗞️ Single-cell transcriptomics reveals anti-inflammatory effects of prednisolone on the hepatic niche in biliary atresia.
🗞️ Single-cell and spatial transcriptomics reveal an arachidonic acid-related cellular atlas in lung adenocarcinoma.
🗞️ Accurate delineation of cellular niches via integrated spatial transcriptomics and histological imaging with SYMOL.
🗞️ Spatial single-cell landscape of tumor-associated macrophages and their crosstalk with the tumor microenvironment.
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Preprints:👇
No preprints found today.
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Papers:👇
🗞️ Inferring stochastic dynamics by biophysical Neural ODE using single-cell transcriptomics.
🗞️ Single-cell transcriptomics reveals anti-inflammatory effects of prednisolone on the hepatic niche in biliary atresia.
🗞️ Single-cell and spatial transcriptomics reveal an arachidonic acid-related cellular atlas in lung adenocarcinoma.
🗞️ Accurate delineation of cellular niches via integrated spatial transcriptomics and histological imaging with SYMOL.
🗞️ Spatial single-cell landscape of tumor-associated macrophages and their crosstalk with the tumor microenvironment.
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Nature
Inferring stochastic dynamics by biophysical Neural ODE using single-cell transcriptomics
Nature Communications - Dou and colleagues present DynNet, a biophysically informed deep learning framework that reconstructs continuous cellular dynamics from time-resolved single-cell data....
Good morning ☕ Here are today's papers!
Preprints:👇
✏️ Integrative Single-Cell and Multi-Cohort Analysis of the Netrin-1 Signaling Pathway Reveals Divergent Prognostic Trends and Sex-Dimorphic Associations in Glioblastoma
✏️ Transcriptome-inferred CIN-like fields mark antigen-presentation-low, immune-cold spatial neighborhoods
✏️ Inflammatory Stromal Aging in Ulcerative Colitis and Colitis-Associated Cancer
✏️ The ATLAS Penalty: Auxiliary-Transformed Location-Aware Smoothing with Applications to Spatial Transcriptomics
✏️ Mapping Tumor-Microenvironment dependencies with TMEformer: A spatial foundation framework enabling in silico perturbation
✏️ A harmonized single-cell RNA-seq atlas of human localized and metastatic prostate cancers and benign tissues
✏️ Benchmarking Static Gene Regulatory Network Reconstruction and Dynamic Transition Probing in Single-Cell Foundation Models.
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Papers:👇
🗞️ Protocol for spatially resolved pathology scores using optimal transport on spatial transcriptomics data.
🗞️ Tonic and early interferons defend against respiratory viruses in primary human lung organoid-derived air-liquid interface cultures.
🗞️ SIRT6-Mediated Deacetylation of ATF3 Promotes Silica-Induced Lung Fibrosis by Enhancing its Nuclear Import via Binding to Importin α.
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Preprints:👇
✏️ Integrative Single-Cell and Multi-Cohort Analysis of the Netrin-1 Signaling Pathway Reveals Divergent Prognostic Trends and Sex-Dimorphic Associations in Glioblastoma
✏️ Transcriptome-inferred CIN-like fields mark antigen-presentation-low, immune-cold spatial neighborhoods
✏️ Inflammatory Stromal Aging in Ulcerative Colitis and Colitis-Associated Cancer
✏️ The ATLAS Penalty: Auxiliary-Transformed Location-Aware Smoothing with Applications to Spatial Transcriptomics
✏️ Mapping Tumor-Microenvironment dependencies with TMEformer: A spatial foundation framework enabling in silico perturbation
✏️ A harmonized single-cell RNA-seq atlas of human localized and metastatic prostate cancers and benign tissues
✏️ Benchmarking Static Gene Regulatory Network Reconstruction and Dynamic Transition Probing in Single-Cell Foundation Models.
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Papers:👇
🗞️ Protocol for spatially resolved pathology scores using optimal transport on spatial transcriptomics data.
🗞️ Tonic and early interferons defend against respiratory viruses in primary human lung organoid-derived air-liquid interface cultures.
🗞️ SIRT6-Mediated Deacetylation of ATF3 Promotes Silica-Induced Lung Fibrosis by Enhancing its Nuclear Import via Binding to Importin α.
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Good morning ☕ Here are today's papers!
Preprints:👇
✏️ Multi-layer transcriptomic characterization of age-related immune dynamics
✏️ Spectral Prompting: Unsupervised Recovery of Human Hair Follicle Cell-Type and Multiscale Systems Architecture from Bulk and Single-Cell RNA-Seq Datasets via Single-Gene Seeded Spectral Unfolding
✏️ A workflow for combined detection of protein interactions and cell types for translational studies
✏️ Heterogeneity-driven adaptive scale graph learning for subcellular spatial transcriptomics
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Papers:👇
🗞️ Optimized nuclei isolation and snRNA-seq reveal oligodendrocyte pathway dysregulation in MOGHE brain tissue from pediatric patients.
🗞️ Protocol for isolating cells from a single cryopreserved gastrointestinal endoscopic biopsy for single-cell RNA sequencing.
🗞️ Expanding canonical cortical cell type markers in the era of single-cell transcriptomics.
🗞️ Nitric Oxide in the Intestinal Stem Cell Niche: A Spatial Model of Nitrosative Stress and Clonal Evolution in Colitis-Associated Colorectal Cancer.
🗞️ Impaired mucociliary clearance in bronchiectasis: the result of a differentiation-delayed airway epithelium?
🗞️ Pan-cancer analysis of single-cell profiles with polygenic signals reveals genetic influences on tumor immunity across cancers.
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Preprints:👇
✏️ Multi-layer transcriptomic characterization of age-related immune dynamics
✏️ Spectral Prompting: Unsupervised Recovery of Human Hair Follicle Cell-Type and Multiscale Systems Architecture from Bulk and Single-Cell RNA-Seq Datasets via Single-Gene Seeded Spectral Unfolding
✏️ A workflow for combined detection of protein interactions and cell types for translational studies
✏️ Heterogeneity-driven adaptive scale graph learning for subcellular spatial transcriptomics
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Papers:👇
🗞️ Optimized nuclei isolation and snRNA-seq reveal oligodendrocyte pathway dysregulation in MOGHE brain tissue from pediatric patients.
🗞️ Protocol for isolating cells from a single cryopreserved gastrointestinal endoscopic biopsy for single-cell RNA sequencing.
🗞️ Expanding canonical cortical cell type markers in the era of single-cell transcriptomics.
🗞️ Nitric Oxide in the Intestinal Stem Cell Niche: A Spatial Model of Nitrosative Stress and Clonal Evolution in Colitis-Associated Colorectal Cancer.
🗞️ Impaired mucociliary clearance in bronchiectasis: the result of a differentiation-delayed airway epithelium?
🗞️ Pan-cancer analysis of single-cell profiles with polygenic signals reveals genetic influences on tumor immunity across cancers.
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Good morning ☕ Here are today's papers!
Preprints:👇
✏️ scDIG: An R Shiny Application for Interactive Density-Based Gating of Single-Cell Proteomic and Transcriptomic Data
✏️ SpatialCCCbench: Standardized Metrics for the Systematic Evaluation of Spatial Cell-Cell Communication Methods
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Papers:👇
🗞️ + A Stromal-Centered Single-Cell Landscape Identifies POSTN Fibroblasts as a High-Risk Stromal Subset in Hepatocellular Carcinoma.
🗞️ The role of the RS1-NEDD4-YAP1 axis orchestrates epithelial-macrophage interplay in COPD.
🗞️ Multiplexed single-cell transcriptomics reveals diverse phenotypic outcomes for pathogenic SHP2 variants.
🗞️ Lactate and Akkermansia muciniphila: Emerging Roles in Inflammatory Bowel Disease and Colorectal Cancer.
🗞️ Optimisation of Xenium automated in situ sequencing for PAXgene-fixed tissue samples.
🗞️ THBS1 SPP1 Multiregional profiling reveals - monocyte-macrophage axis drives immunosuppression and outcome in colorectal liver metastases.
🗞️ Comprehensive bioinformatics analysis of EXOSC family genes in lung adenocarcinoma.
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Preprints:👇
✏️ scDIG: An R Shiny Application for Interactive Density-Based Gating of Single-Cell Proteomic and Transcriptomic Data
✏️ SpatialCCCbench: Standardized Metrics for the Systematic Evaluation of Spatial Cell-Cell Communication Methods
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Papers:👇
🗞️ + A Stromal-Centered Single-Cell Landscape Identifies POSTN Fibroblasts as a High-Risk Stromal Subset in Hepatocellular Carcinoma.
🗞️ The role of the RS1-NEDD4-YAP1 axis orchestrates epithelial-macrophage interplay in COPD.
🗞️ Multiplexed single-cell transcriptomics reveals diverse phenotypic outcomes for pathogenic SHP2 variants.
🗞️ Lactate and Akkermansia muciniphila: Emerging Roles in Inflammatory Bowel Disease and Colorectal Cancer.
🗞️ Optimisation of Xenium automated in situ sequencing for PAXgene-fixed tissue samples.
🗞️ THBS1 SPP1 Multiregional profiling reveals - monocyte-macrophage axis drives immunosuppression and outcome in colorectal liver metastases.
🗞️ Comprehensive bioinformatics analysis of EXOSC family genes in lung adenocarcinoma.
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Good morning ☕ Here are today's papers!
Preprints:👇
✏️ PerturbPlan: An analytical framework for designing Perturb-seq experiments
✏️ Atlas-Level Single-Cell and Spatial Transcriptomics Data Integration via PRIME
✏️ Decoding Immune Reconstitution Failure in People Living with HIV through Single-cell Genomics
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Papers:👇
🗞️ Spatial transcriptomics reveals influence of microenvironment on intrinsic fates in melanoma therapy resistance.
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Preprints:👇
✏️ PerturbPlan: An analytical framework for designing Perturb-seq experiments
✏️ Atlas-Level Single-Cell and Spatial Transcriptomics Data Integration via PRIME
✏️ Decoding Immune Reconstitution Failure in People Living with HIV through Single-cell Genomics
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Papers:👇
🗞️ Spatial transcriptomics reveals influence of microenvironment on intrinsic fates in melanoma therapy resistance.
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Good morning ☕ Here are today's papers!
Preprints:👇
No preprints found today.
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Papers:👇
No papers found today.
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Preprints:👇
No preprints found today.
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Papers:👇
No papers found today.
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Good morning ☕ Here are today's papers!
Preprints:👇
No preprints found today.
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Papers:👇
No papers found today.
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Preprints:👇
No preprints found today.
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Papers:👇
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Good morning ☕ Here are today's papers!
Preprints:👇
✏️ SpatialClaw: A Memory-Augmented Autonomous Ecosystem for Spatial Omics Analysis
✏️ Highly Constrained Kinetic Models for Single-Cell Gene Expression Analysis
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Papers:👇
🗞️ Decoding cellular population dynamics through mechanistic modelling and statistical data analysis.
🗞️ Integration of single-cell RNA-sequencing and machine learning identifies GRN and FCER1G as potential peroxisomal targets in influenza pathogenesis.
🗞️ SOFisher: reinforcement learning-guided experiment designs for spatial omics.
🗞️ Integrative single-cell RNA-seq and transcriptomic analysis uncovers cellular heterogeneity and immunotherapy resistance mechanisms in colorectal cancer.
🗞️ Benchmarking the prediction of responding cells to perturbations affecting both gene expression and cellular abundance using scRNA sequencing.
🗞️ Mechanisms and reversal strategies of liver fibrosis: from regulation of cell fate to clinical translation.
🗞️ Identifying potential ligand-receptor interactions by integrating LSTM network and the attention mechanism for cell-cell communication prediction.
🗞️ SDMCC: Sample-wise Debiased Multilevel Contrastive Clustering for Single-cell Gene Expression Data.
🗞️ Toward simultaneous pseudo-space reconstruction and cell-type deconvolution of single-cell spatial transcriptome using SpaDicer.
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Preprints:👇
✏️ SpatialClaw: A Memory-Augmented Autonomous Ecosystem for Spatial Omics Analysis
✏️ Highly Constrained Kinetic Models for Single-Cell Gene Expression Analysis
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Papers:👇
🗞️ Decoding cellular population dynamics through mechanistic modelling and statistical data analysis.
🗞️ Integration of single-cell RNA-sequencing and machine learning identifies GRN and FCER1G as potential peroxisomal targets in influenza pathogenesis.
🗞️ SOFisher: reinforcement learning-guided experiment designs for spatial omics.
🗞️ Integrative single-cell RNA-seq and transcriptomic analysis uncovers cellular heterogeneity and immunotherapy resistance mechanisms in colorectal cancer.
🗞️ Benchmarking the prediction of responding cells to perturbations affecting both gene expression and cellular abundance using scRNA sequencing.
🗞️ Mechanisms and reversal strategies of liver fibrosis: from regulation of cell fate to clinical translation.
🗞️ Identifying potential ligand-receptor interactions by integrating LSTM network and the attention mechanism for cell-cell communication prediction.
🗞️ SDMCC: Sample-wise Debiased Multilevel Contrastive Clustering for Single-cell Gene Expression Data.
🗞️ Toward simultaneous pseudo-space reconstruction and cell-type deconvolution of single-cell spatial transcriptome using SpaDicer.
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Good morning ☕ Here are today's papers!
Preprints:👇
No preprints found today.
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Papers:👇
🗞️ Beyond Suppression: The Plasticity, Dysfunction, and Therapeutic Reprogramming of Regulatory T Cells in Inflammatory Bowel Disease.
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Preprints:👇
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Papers:👇
🗞️ Beyond Suppression: The Plasticity, Dysfunction, and Therapeutic Reprogramming of Regulatory T Cells in Inflammatory Bowel Disease.
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Good morning ☕ Here are today's papers!
Preprints:👇
No preprints found today.
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Papers:👇
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Preprints:👇
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Good morning ☕ Here are today's papers!
Preprints:👇
No preprints found today.
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Papers:👇
🗞️ Integrative multi-omics analysis identifies LIPA as a prognostic hub and ferroptosis regulator in lung adenocarcinoma.
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Preprints:👇
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Papers:👇
🗞️ Integrative multi-omics analysis identifies LIPA as a prognostic hub and ferroptosis regulator in lung adenocarcinoma.
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SpringerLink
Integrative multi-omics analysis identifies LIPA as a prognostic hub and ferroptosis regulator in lung adenocarcinoma
Molecular and Cellular Biochemistry - Lung adenocarcinoma (LUAD) remains one of the leading causes of cancer mortality, underscoring the urgent need for biomarkers and therapeutic targets rooted in...
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Good morning ☕ Here are today's papers!
Preprints:👇
No preprints found today.
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Papers:👇
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Preprints:👇
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