دکتر #فیروزه_بنیصدر: درمان بیماران #کووید۱۹ با #کورتون باعث کاهش قابل توجه مرگ و میر در مریض‌خانه بود
Corticosteroid therapy for patients with CoVID-19 pneumonia: a before-after study
Firouzé BANI-SADR
National Institutes of Health
Abstract
https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7342082/
Background
Anti-inflammatory drugs such as corticosteroids may beneficially modulate the host inflammatory response to CoVID-19 pneumonia.
Aims
To evaluate the impact of addition of corticosteroids to the hospital protocol for treatment of suspected or confirmed CoVID-19 pneumonia on rates of death or intensive care unit (ICU) admission.
Methods
A before-after study was performed to evaluate the effect of addition of corticosteroids to our institution's COVID-19 treatment protocol on hospital mortality.
Results
Between March 3rd and April 14th 2020, 257 patients with CoVID-19 diagnosis were included. As corticosteroids were wide used since 27 March 2020, two periods were considered for the purposes of our study: the before period from March 3rd to 20th (n= 85) and the “after period” (n=172) from March 26th to April 14th 2020.
The “after” period was associated with a lower risk of death (HR 0.47; 95% CI, 0.23 - 0.97; p=0.04), and a lower risk of intensive care admission or death before ICU admission (HR 0.37 95% CI 0.21 - 0.64; p=0.0005) by multivariate analysis adjusted for age, National Early Warning score and institutionalization status.
Conclusions
In the “after period”, the addition of corticosteroids to our institution's CoVID-19 treatment protocol was associated with a significant reduction in hospital mortality.
Keywords: COVID-19, SARS CoV2, COVID-19 pneumonia, Corticosteroid
#فیروزه_بنیصدر
#فیروزه_بنیصدر
#فیروزه_بنی_صدر
#دکتر_بنیصدر
#دکتر_بنیصدر
#دکتر_بنی_صدر
#دکتر_فیروزه_بنیصدر
#دکتر_فیروزه_بنیصدر
#دکتر_فیروزه_بنی_صدر
#کووید۱۹
#بنیصدر
#اعدام_نکنید
#کرونا
#ویروس
#کروناویروس
❊
https://www.balatarin.com/permlink/2020/7/18/5360043
❊
https://twitter.com/sedaratmd/status/1284275783138148352
❊
https://www.instagram.com/p/CCw0GWSJJte/
❊
https://t.me/sedaratMD/1096
❊
https://chat.whatsapp.com/IT11IqMZ44v9L62gPRghhu
❊
https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7342082/
Corticosteroid therapy for patients with CoVID-19 pneumonia: a before-after study
Firouzé BANI-SADR
National Institutes of Health
Abstract
https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7342082/
Background
Anti-inflammatory drugs such as corticosteroids may beneficially modulate the host inflammatory response to CoVID-19 pneumonia.
Aims
To evaluate the impact of addition of corticosteroids to the hospital protocol for treatment of suspected or confirmed CoVID-19 pneumonia on rates of death or intensive care unit (ICU) admission.
Methods
A before-after study was performed to evaluate the effect of addition of corticosteroids to our institution's COVID-19 treatment protocol on hospital mortality.
Results
Between March 3rd and April 14th 2020, 257 patients with CoVID-19 diagnosis were included. As corticosteroids were wide used since 27 March 2020, two periods were considered for the purposes of our study: the before period from March 3rd to 20th (n= 85) and the “after period” (n=172) from March 26th to April 14th 2020.
The “after” period was associated with a lower risk of death (HR 0.47; 95% CI, 0.23 - 0.97; p=0.04), and a lower risk of intensive care admission or death before ICU admission (HR 0.37 95% CI 0.21 - 0.64; p=0.0005) by multivariate analysis adjusted for age, National Early Warning score and institutionalization status.
Conclusions
In the “after period”, the addition of corticosteroids to our institution's CoVID-19 treatment protocol was associated with a significant reduction in hospital mortality.
Keywords: COVID-19, SARS CoV2, COVID-19 pneumonia, Corticosteroid
#فیروزه_بنیصدر
#فیروزه_بنیصدر
#فیروزه_بنی_صدر
#دکتر_بنیصدر
#دکتر_بنیصدر
#دکتر_بنی_صدر
#دکتر_فیروزه_بنیصدر
#دکتر_فیروزه_بنیصدر
#دکتر_فیروزه_بنی_صدر
#کووید۱۹
#بنیصدر
#اعدام_نکنید
#کرونا
#ویروس
#کروناویروس
❊
https://www.balatarin.com/permlink/2020/7/18/5360043
❊
https://twitter.com/sedaratmd/status/1284275783138148352
❊
https://www.instagram.com/p/CCw0GWSJJte/
❊
https://t.me/sedaratMD/1096
❊
https://chat.whatsapp.com/IT11IqMZ44v9L62gPRghhu
❊
https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7342082/
PubMed Central (PMC)
Corticosteroid therapy for patients with COVID-19 pneumonia: a before–after study
Anti-inflammatory drugs such as corticosteroids may beneficially modulate the host inflammatory response to coronavirus disease 2019 (COVID-19) pneumonia. The aim of this study was to evaluate the impact of addition of corticosteroids to the hospital ...