"Dr Mike Yeadon, former Chief Scientific Officer of Pfizer's A&R Research Unit, and a vocal critic of the Government’s lockdown approach, considers further border restrictions to be a bad idea. He tells us: “Unless you’re an experienced biologist, you might think what’s happening at the borders makes sense. I’m afraid it does not, in my opinion. I spoke yesterday to a highly experienced immunologist and their view mirrors mine: that this is senseless.”  
Elaborating on widespread fears of new variants emerging, either abroad or on home soil, he says: “Mutation in SARS-COV-2 is really slow, and these mutations remain 99.8 per cent the same as the original. So natural immunity already gained will work perfectly well and the same is true for immunity gained through vaccination; albeit to a slightly lesser extent. It’s bonkers, therefore, to close borders in the interests of keeping out ‘foreign mutants’. First, they’re irrelevant as regards to immunity, as explained. Second, we’re making our own mutants – these occur in the UK slowly over time, irrespective of borders.”  
https://www.telegraph.co.uk/travel/news/experts-predict-quarantine-hotels-could-us-next-summer/

KEEP IN MIND
The pandemic didn’t use erroneous data to model an inflated estimate of mortality.

The pandemic didn’t write hyperbolic headlines.

The pandemic didn’t create overly-inclusive reporting requirements.

The pandemic didn’t design a test unfit for purpose...

1/5

The pandemic didn’t quarantine the healthy.

The pandemic didn’t initiate lockdowns.

The pandemic didn’t decimate small businesses.

The pandemic didn’t close schools, some going on a full year.

The pandemic didn’t reduce the healthcare workforce...

2/5

The pandemic didn’t ignore basic tenets of public health.

The pandemic didn’t exploit itself for political leverage.



The pandemic didn’t create a lucrative products/industries dependent upon its continuation.

The pandemic didn’t siphon resources from other deadly threats

3/5

The pandemic didn’t use fear to control people’s behavior.

The pandemic didn’t threaten people with social, financial, and professional ostratcization for pointing out the harms caused by any of the above.

People did those things.

They were not inevitable...

4/5

As we sort through the outcomes of the last year, it’s critical that we trace each impact back to its source.

Pretending like all of this destruction was inevitable does nothing to help us fix the damage now, & will do nothing to help us make better decisions in the future.

5/5

AJ Kay
https://threadreaderapp.com/thread/1358092397956108290.html

"The doctor Johan Anmuth (The Book of Vision), believes in a medicine in which the body is not just a sack containing organs & fluids: he treats his patients first by listening to their stories & fears, as if he were at the same time a scientist & a psychoanalyst ante litteram"
https://watch.eventive.org/sfindiefest2021/play/5fd3f9c73ee6300037fba02f

"Conclusion: In the intervention arm, early viral clearance was observed and no side effects were documented. Therefore ivermectin is a potential addition to the standard care of treatment in COVID-19 patients."
https://www.medrxiv.org/content/10.1101/2021.02.02.21250840v1

Karl Popper's Falsification Principle: how to divide science from non-science. Science: For a theory to be considered scientific it must be able to be tested (for medicine this means with evidence) and conceivably proven false. "The science" is only what could be proven false. For Popper, science should always attempt to disprove a theory, rather than attempt to continually support theoretical hypotheses (eg that epidemiological modelling based on limited data & possibly flawed assumptions is a reflection of reality despite evidence to the contrary).

Scientific progress happens through proving theories wrong or partially wrong. The moment something is declared outside the boundaries of being able to be proved wrong (eg lockdowns, face masks & vaccines) then it is no longer science but a faith based set of unmovable beliefs. The true scientist will always seek to find out how a PCR test can't possibly diagnose a disease, why cloth masks increase infections rather than decrease them, why lockdowns kill rather than save lives, why vaccines which skipped years of human trials can cause many deaths, etc. Because that is the only way in which scientific progress can be made: testing theories until the theories, or part of them, can be proved wrong and a new or modified theory is required to explain that aspect of reality, which in turn can be tested and improved. That is science.

A Tribute to Terrence Malick: An Evolution of Thought on Film - Hollywood Insider
https://www.hollywoodinsider.com/terrence-malick-tribute/

A Tribute to Terrence Malick: An Evolution of Thought on Film
https://youtu.be/ep098F8wKb0

"The majority of antigens recognized by T cells fall outside the spike protein, while the vast majority is non-RBD. Natural immunity is therefore much broader than that triggered by vaccines, and the effect of spike mutations is predicted to be smaller." @gerdosi
https://www.cell.com/cell-reports-medicine/fulltext/S2666-3791(21)00015-X#%20

"Polyethylene glycol (PEG)-coated nanopharmaceuticals can cause mild to severe hypersensitivity reactions (HSRs), which can occasionally be life threatening or even lethal. The phenomenon represents an unsolved immune barrier to the use of these drugs, yet its mechanism is poorly understood. This study showed that a single i.v. injection in pigs of a low dose of PEGylated liposomes (Doxebo) induced a massive rise of anti-PEG IgM in blood, peaking at days 7–9 and declining over 6 weeks. Bolus injections of PEG-liposomes during seroconversion resulted in anaphylactoid shock (pseudo-anaphylaxis) within 2–3 min, although similar treatments of naı̈ve animals led to only mild hemodynamic disturbance. Parallel measurement of pulmonary arterial pressure (PAP) and sC5b-9 in blood, taken as measures of HSR and complement activation, respectively, showed a concordant rise of the two variables within 3 min and a decline within 15 min, suggesting a causal relationship between complement activation and pulmonary hypertension. We also observed a rapid decline of anti-PEG IgM in the blood within minutes, increased binding of PEGylated liposomes to IgM+ B cells in the spleen of immunized animals compared to control, and increased C3 conversion by PEGylated liposomes in the serum of immunized pigs. These observations taken together suggest rapid binding of anti-PEG IgM to PEGylated liposomes, leading to complement activation via the classical pathway, entailing anaphylactoid shock and accelerated blood clearance of liposome–IgM complexes. These data suggest that complement activation plays a causal role in severe HSRs to PEGylated nanomedicines and that pigs can be used as a hazard identification model to assess the risk of HSRs in preclinical safety studies."
https://pubs.acs.org/doi/10.1021/acsnano.9b03942

Watch Is it True that the New Variants are Very Dangerous?
https://vimeo.com/507658201

"Dear Editor
History is littered with examples of the atrocities which ensue when doctors abandon their traditional principles and judgement in favour of unquestioning subservience to government diktat – medical involvement in torture, human experimentation and psychiatric punishment of political dissidents being familiar examples.
Abbasi takes as axiomatic that there was no prior immunity in the population, that lockdowns are effective, that computer modelling is realistic, that statistics have been accurate and that WHO statements are reliable. All of these parameters have been widely challenged by knowledgeable and conscientious researchers whose findings were often disregarded, censored or vilified.
From a medical perspective, it was clear early on in the crisis that disregarding clinical acumen in favour of blind obedience to abnormal ventilation measures, reliance on an unsuitable laboratory test for diagnosis and management, and abandoning the duty of care to elderly hospitalised patients and those awaiting diagnosis and treatment of serious diseases, would create severe problems down the line.
Doctors who had empirically found effective pharmaceutical remedies and preventative treatments were ignored, or worse, denigrated or silenced. Information regarding helpful dietary supplements was suppressed.
This was further compounded by rule-changes to death certification, coroners’ instructions, autopsy guidelines, DNR notices and the cruel social isolation policy enforcement regarding family visits to the sick and dying.
When medical professionals allow themselves to be manipulated by corrupt politicians and influenced by media propaganda instead of being guided by their own ethical principles and common sense based on decades of clinical experience, the outlook becomes very bleak indeed.
Historically, public respect for and trust in doctors has exceeded that awarded to politicians. The unquestioning capitulation of medicine to an authoritarian executive and predatory corporate power may have undermined the doctor-patient relationship for a generation." Janet Menage, GP, retired
https://www.bmj.com/content/372/bmj.n314/rr-8

Mike Yeadon: "Robin, I’ve just spent over an hour reading (some of) this wonderful paper! They find several HUNDRED different T-cell epitopes, which don’t correlate particularly well with epitopes targeted by antibodies. The huge T-cell repertoire is not only very reassuring in relation to avoiding immune escape via mutations (which are very slight in proportion to the FL virus sequences) but the lack of correlation to antibody epitopes strongly supports NOT basing policy on whether or not a variant is bound more or less well by a specific antibody.
As previously discussed, this is an exceptionally large virus, affording a large number of sequences recognised by T-cells as unique & foreign. This isn’t surprising. What is surprising is just how concerned some presumably non immunologists are with trivial extents of variation."
https://www.cell.com/cell-reports-medicine/fulltext/S2666-3791(21)00015-X#%20

On the seasonality of coronaviruses. All going like clockwork I would say. Thanks Dr Simon t.me/goddek

The percentage of tests positive for human coronaviruses (HCoVs) -OC43, -NL63, -229E, and -HKU1 reported to the National Respiratory and Enteric Viruses Surveillance System (NREVSS) by week, stratified by US Census Region, July 2014–June 2017.
https://pubmed.ncbi.nlm.nih.gov/29427907/

Age distribution of human coronaviruses (HCoVs) -229E, -HKU1, -NL63 & -OC43 positive tests with age available reported to NREVSS via the Public Health Laboratory Interoperability Project (PHLIP), from July 2014–June 2017. Specimens with more than one coronavirus detected excluded
https://pubmed.ncbi.nlm.nih.gov/29427907/

Take a look at human coronavirus OC43. This can be as deadly if untreated for older people as SARSCoV2. We have always had it. There has never been a huge deal made about it. "These findings underscore the virulence of human CoV-OC43 [endemic common cold coronavirus] in elderly populations" out of 95 infections, 8 died (8% mortality rate, 92% survival rate), 6 with pneumonia.
https://www.ncbi.nlm.nih.gov/pmc/articles/PMC2095096/

"In OECD countries. the mortality rate for SARS-CoV-2..is not significantly different from that for common coronaviruses identified in public hospitals of Marseille, France (0.8%)."
https://www.sciencedirect.com/science/article/abs/pii/S0924857920300972

Watch (ENG) OVALexclusive : Urgent Message from Prof. Sucharit Bhakdi
https://vimeo.com/507137123