Forwarded from Robin Monotti + Cory Morningstar
Patrick Whelan MD PhD:"I am concerned about the possibility that the new vaccines aimed at creating immunity against the SARS-CoV-2 spike protein (including the mRNA vaccines of Moderna and Pfizer) have the potential to cause microvascular injury to the brain, heart, liver, and kidneys in a way that does not currently appear to be assessed in safety trials of these potential drugs...it appears that the viral spike protein that is the target of the major SARS-CoV-2 vaccines is also one of the key agents causing the damage to distant organs that may include the brain, heart, lung, and kidney. Before any of these vaccines are approved for widespread use in humans, it is important to assess in vaccinated subjects the effects of vaccination on the heart (perhaps using cardiac MRI, as Puntmann et al. did). Vaccinated patients could also be tested for distant tissue damage in deltoid area skin biopsies, as employed by Magro et al. As important as it is to quickly arrest the spread of the virus by immunizing the population, it would be vastly worse if hundreds of millions of people were to suffer long-lasting or even permanent damage to their brain or heart microvasculature as a result of failing to appreciate in the short-term an unintended effect of full-length spike protein-based vaccines on these other organs.
Particular caution will be required with regard to the potential widespread vaccination of children before there are any real data on the safety or effectiveness of these vaccines in pediatric trials that are only now beginning."
Regulations.gov
https://www.regulations.gov/document/FDA-2020-N-1898-0246
Particular caution will be required with regard to the potential widespread vaccination of children before there are any real data on the safety or effectiveness of these vaccines in pediatric trials that are only now beginning."
Regulations.gov
https://www.regulations.gov/document/FDA-2020-N-1898-0246
Forwarded from OffGuardian (official) (OffG Admin)
Doctors & Scientists Write to European Medicines Agency Warning of COVID-19 Vaccine Dangers
https://wp.me/paXmj6-jft
https://wp.me/paXmj6-jft
Forwarded from 21st Century Wire
Doctors and Scientists Challenge European Medicines Agency on COVID-19 Vaccine Danger
https://21stcenturywire.com/2021/03/11/doctors-and-scientists-challenge-european-medicines-agency-warning-of-covid-19-vaccine-dangers/
https://21stcenturywire.com/2021/03/11/doctors-and-scientists-challenge-european-medicines-agency-warning-of-covid-19-vaccine-dangers/
21st Century Wire
Doctors and Scientists Challenge European Medicines Agency on COVID-19 Vaccine Danger
<strong>Doctors for COVID Ethics</strong> | A group of eminent international doctors and medical professions has issued a letter questioning the safety, ethics and legality of the current vaccine push.
CDP-2021-0038.pdf
213 KB
This briefing has been produced ahead of the debate to be held in Westminster Hall on Monday 15 March 2021 at 4.30 pm on e-petition 569957 (Covid-19 vaccine passports).
DEBATE PACK
Number CDP 2021-0038 , 11 March 2021
Debate on an e-petition
relating to Covid-19
vaccine passports
CDP-2021-0038.pdf
DEBATE PACK
Number CDP 2021-0038 , 11 March 2021
Debate on an e-petition
relating to Covid-19
vaccine passports
CDP-2021-0038.pdf
VITAMIN D ☀️.
Download this app on your mobile: dminder
"Wherever you go in the world, dminder tracks the sun and tells you when you can get Vitamin D. The stopwatch interface lets you set your session target by either amount of D to get or time. Then it will count up or down to your target, applying all the factors that determine how much D you can get: skin tone, age, weight, amount of skin exposed. All your doses of D, from the sun or supplements, are used to continuously estimate your current level. Developed with world authority on Vitamin D, Dr. Michael Holick."
http://dminder.ontometrics.com/
Download this app on your mobile: dminder
"Wherever you go in the world, dminder tracks the sun and tells you when you can get Vitamin D. The stopwatch interface lets you set your session target by either amount of D to get or time. Then it will count up or down to your target, applying all the factors that determine how much D you can get: skin tone, age, weight, amount of skin exposed. All your doses of D, from the sun or supplements, are used to continuously estimate your current level. Developed with world authority on Vitamin D, Dr. Michael Holick."
http://dminder.ontometrics.com/
I now listened to this pathologist, Dr Ryan Cole, who explains very clearly points 2 (vitamin D) and 3 (early treatment) of the Monotti Protocol. All you need to listen to are the first 25 minutes. https://youtu.be/oA-fTaGadyc
Gut bacteria and vitamin D: What is the link?
"We were surprised to find that microbiome diversity — the variety of bacteria types in a person’s gut — was closely associated with active vitamin D but not the precursor form,” says senior author of the study Dr. Deborah Kado, director of the Osteoporosis Clinic at UC San Diego Health.
“Greater gut microbiome diversity is thought to be associated with better health in general,” she adds.
https://www.medicalnewstoday.com/articles/gut-bacteria-and-vitamin-d-what-is-the-link#Stores-of-inactive-vitamin-D
"We were surprised to find that microbiome diversity — the variety of bacteria types in a person’s gut — was closely associated with active vitamin D but not the precursor form,” says senior author of the study Dr. Deborah Kado, director of the Osteoporosis Clinic at UC San Diego Health.
“Greater gut microbiome diversity is thought to be associated with better health in general,” she adds.
https://www.medicalnewstoday.com/articles/gut-bacteria-and-vitamin-d-what-is-the-link#Stores-of-inactive-vitamin-D
Medical News Today
Gut bacteria and vitamin D: What is the link?
An intriguing new study finds a significant association between gut bacteria diversity and the levels of active vitamin D in the body.
"The email identified “a significant difference in % RNA integrity/truncated species” between the clinical batches and proposed commercial batches—from around 78% to 55%. The root cause was unknown and the impact of this loss of RNA integrity on safety and efficacy of the vaccine was “yet to be defined,” the email said.
One of the most important variables relevant to all mRNA vaccines that has thus far received scant attention in the clinical community. It is an issue relevant not just to Pfizer-BioNTech’s vaccine but also to those produced by Moderna, CureVac, and others ,4 as well as a “second generation” mRNA vaccine being pursued by Imperial College London.5
RNA instability is one of the biggest hurdles for researchers developing nucleic acid based vaccines. It is the primary reason for the technology’s stringent cold chain requirements and has been addressed by encapsulating the mRNA in lipid nanoparticles (box).
“The complete, intact mRNA molecule is essential to its potency as a vaccine,” professor of biopharmaceutics Daan J.A. Crommelin and colleagues wrote in a review article in The Journal of Pharmaceutical Sciences late last year. “Even a minor degradation reaction, anywhere along a mRNA strand, can severely slow or stop proper translation performance of that strand and thus result in the incomplete expression of the target antigen.”
The Medicines and Healthcare products Regulatory Agency, the UK’s medicines regulator, acknowledged the lack of a specified percentage RNA integrity, but declined to provide further detail. “The specification limit acceptance criteria are commercially confidential,” the agency said in an email.
https://www.bmj.com/content/372/bmj.n627
One of the most important variables relevant to all mRNA vaccines that has thus far received scant attention in the clinical community. It is an issue relevant not just to Pfizer-BioNTech’s vaccine but also to those produced by Moderna, CureVac, and others ,4 as well as a “second generation” mRNA vaccine being pursued by Imperial College London.5
RNA instability is one of the biggest hurdles for researchers developing nucleic acid based vaccines. It is the primary reason for the technology’s stringent cold chain requirements and has been addressed by encapsulating the mRNA in lipid nanoparticles (box).
“The complete, intact mRNA molecule is essential to its potency as a vaccine,” professor of biopharmaceutics Daan J.A. Crommelin and colleagues wrote in a review article in The Journal of Pharmaceutical Sciences late last year. “Even a minor degradation reaction, anywhere along a mRNA strand, can severely slow or stop proper translation performance of that strand and thus result in the incomplete expression of the target antigen.”
The Medicines and Healthcare products Regulatory Agency, the UK’s medicines regulator, acknowledged the lack of a specified percentage RNA integrity, but declined to provide further detail. “The specification limit acceptance criteria are commercially confidential,” the agency said in an email.
https://www.bmj.com/content/372/bmj.n627
The BMJ
The EMA covid-19 data leak, and what it tells us about mRNA instability
Leaked documents show that some early commercial batches of Pfizer-BioNTech’s covid-19 vaccine had lower than expected levels of intact mRNA, prompting wider questions about how to assess this novel vaccine platform, writes Serena Tinari
As it conducted…
As it conducted…
Lipid nanoparticles—where do they go and what do they do?
Over the years, researchers attempted to resolve intrinsic instability by encapsulating mRNA in nanocarriers made of polymers, lipids, or inorganic materials. Lipid nanoparticles (LNPs) were chosen by Moderna, Pfizer-BioNTech, CureVac, and Imperial College London for their covid-19 vaccines.
JW Ulm, a gene therapy specialist who has published on tissue targeting of therapeutic vectors,13 raised concerns about the biodistribution of LNPs: “At present, relatively little has been reported on the tissue localisation of the LNPs used to encase the SARS-CoV-2 spike protein-encoding messenger RNA, and it is vital to have more specific information on precisely where the liposomal nanoparticles are going after injection.”
Pharmacokinetic studies, with independent laboratory confirmation, are essential to ascertain potential cytotoxicity and macroscopic toxicity, especially given the likelihood of booster injections over months or years, since the tissue trafficking patterns of the mRNA vaccine payload will determine which cells and tissues are killed by cytotoxic T-cells in each round.”
Regulators and manufacturers contacted by The BMJ for this article did not wish to address any of the questions raised by Ulm’s rapid response.
https://www.bmj.com/content/372/bmj.n627
Over the years, researchers attempted to resolve intrinsic instability by encapsulating mRNA in nanocarriers made of polymers, lipids, or inorganic materials. Lipid nanoparticles (LNPs) were chosen by Moderna, Pfizer-BioNTech, CureVac, and Imperial College London for their covid-19 vaccines.
JW Ulm, a gene therapy specialist who has published on tissue targeting of therapeutic vectors,13 raised concerns about the biodistribution of LNPs: “At present, relatively little has been reported on the tissue localisation of the LNPs used to encase the SARS-CoV-2 spike protein-encoding messenger RNA, and it is vital to have more specific information on precisely where the liposomal nanoparticles are going after injection.”
Pharmacokinetic studies, with independent laboratory confirmation, are essential to ascertain potential cytotoxicity and macroscopic toxicity, especially given the likelihood of booster injections over months or years, since the tissue trafficking patterns of the mRNA vaccine payload will determine which cells and tissues are killed by cytotoxic T-cells in each round.”
Regulators and manufacturers contacted by The BMJ for this article did not wish to address any of the questions raised by Ulm’s rapid response.
https://www.bmj.com/content/372/bmj.n627
The BMJ
The EMA covid-19 data leak, and what it tells us about mRNA instability
Leaked documents show that some early commercial batches of Pfizer-BioNTech’s covid-19 vaccine had lower than expected levels of intact mRNA, prompting wider questions about how to assess this novel vaccine platform, writes Serena Tinari
As it conducted…
As it conducted…
Face_masks_discrimination_template_letter.pdf
85.1 KB
UK: Face mask discrimination template letter.
People exempt from wearing a face covering are entitled to go about their business on the same basis as everyone else, but on just one proviso, the words "I'm exempt" must be clearly stated if challenged This is unsatisfactory for some, but the Guidance does allow service providers to check if someone wearing a mask is exempt or simply forgotten to wear a face covering. But that is as far as any service provider can legitimately go.
Again HMG states, "...we make it clear that some people may have a ‘reasonable excuse’ for not wearing face coverings, and that people do not need to prove they are exempt and should not be challenged about this. We are also clear that people should remove their face coverings to aid communication where asked, and that those accompanying or assisting people for whom a face covering will inhibit communication are not required to wear face coverings".
Face_masks_discrimination_template_letter.pdf
People exempt from wearing a face covering are entitled to go about their business on the same basis as everyone else, but on just one proviso, the words "I'm exempt" must be clearly stated if challenged This is unsatisfactory for some, but the Guidance does allow service providers to check if someone wearing a mask is exempt or simply forgotten to wear a face covering. But that is as far as any service provider can legitimately go.
Again HMG states, "...we make it clear that some people may have a ‘reasonable excuse’ for not wearing face coverings, and that people do not need to prove they are exempt and should not be challenged about this. We are also clear that people should remove their face coverings to aid communication where asked, and that those accompanying or assisting people for whom a face covering will inhibit communication are not required to wear face coverings".
Face_masks_discrimination_template_letter.pdf
Forwarded from Eshani King
Moderna's own 2012 research shows LNPs end up in your brain and in fact everywhere. Potential in brain to cause autoimmune reactions, inflammation and cause protein mis-folding (dementia/Alzheimer's risk?). Potential to impact gametes in reproductive organs.
https://thehighwire.com/videos/neuroscientists-concerns-about-covid-vaccines/
https://thehighwire.com/videos/neuroscientists-concerns-about-covid-vaccines/
The HighWire
NEUROSCIENTIST’S CONCERNS ABOUT COVID VACCINES
NEUROSCIENTIST’S CONCERNS ABOUT COVID VACCINES Neuroscientist Chris Shaw PhD shares his concerns about the mRNA #Covid19 vaccines and explains Moderna’s own data demonstrating mRNA can cross the blood-brain barrier. #ChrisShaw #DoctorsSpeakUp #Neuroscience…
"Denmark, Norway, Iceland, Austria, Estonia, Lithuania, Luxembourg, Italy, and Latvia—have suspended use of AstraZeneca’s vaccine.
On 10 March the EMA said that Austria had suspended the use of a batch of AstraZeneca vaccines after one person had multiple thrombosis diagnosed and died 10 days after vaccination. Another person was admitted to hospital with pulmonary embolism after being vaccinated and is now recovering. The EMA said that two other reports of thromboembolic event cases had also been received..
https://www.bmj.com/content/372/bmj.n699
On 10 March the EMA said that Austria had suspended the use of a batch of AstraZeneca vaccines after one person had multiple thrombosis diagnosed and died 10 days after vaccination. Another person was admitted to hospital with pulmonary embolism after being vaccinated and is now recovering. The EMA said that two other reports of thromboembolic event cases had also been received..
https://www.bmj.com/content/372/bmj.n699
The BMJ
Covid-19: European countries suspend use of Oxford-AstraZeneca vaccine after reports of blood clots
Denmark has temporarily suspended use of the Oxford-AstraZeneca covid-19 vaccine as a precautionary move after reports of blood clots and one death. However, the European Medicines Agency (EMA) and the UK’s regulatory body have said that there is no indication…
Forwarded from Fifi 4 Freedom_A Stand in the Park UK
Please feel free to print these off to promote your Stands! 🙌