A 7-year-old boy presents with headaches, vomiting, and ataxia. MRI reveals a midline cerebellar mass. A biopsy shows small, round blue cells and Homer-Wright rosettes. Which microscopic feature is characteristic of this tumor?
• A. Psammoma bodies
• B. Pseudopalisading necrosis
• C. Perivascular pseudorosettes
• D. Homer-Wright rosettes

Ok guys, see you tomorrow. And will definitely answer the queries and we will have a quick live session soon 🙂

A 16-year-old girl presents with a slowly enlarging, painless mass on her tibia. Radiographic findings show a bony outgrowth capped with cartilage. What is the most likely diagnosis?
A) Osteochondroma
😎 Osteosarcoma
C) Chondrosarcoma
D) Ewing sarcoma

20-year-old man presents with progressively worsening knee pain and a mass around the distal femur. An X-ray reveals a sunburst pattern of bone formation and a Codman triangle. Biopsy shows malignant osteoid production by atypical cells. What is the most likely diagnosis?

A) Osteochondroma
😎 Osteosarcoma
C) Chondrosarcoma
D) Ewing sarcoma

t(11,22). -classically seen in ?

t (X,18) - classically seen in ?

Epiphyseal lesion. Diagnosis ?

Neurofibroma or Schwannoma ?

Osteopetrosis, also known as “marble bone disease,” is primarily caused by:

A. Increased osteoclast activity
B. Impaired osteoclast function
C. Excess osteoblast activity
D. Increased collagen deposition

Spotter bone disease. Clue - Heavy skull

In Paget’s disease of bone, which phase is characterized by excessive osteoclastic activity and bone resorption?

• A. Initial osteoblastic phase
• B. Mixed phase
• C. Sclerotic phase
• D. Osteoclastic phase

Rheumatoid arthritis (RA) is a systemic autoimmune disorder that primarily affects which structure in the joints?

• A. Subchondral bone
• B. Articular cartilage
• C. Synovial membrane
• D. Joint capsule

In osteoarthritis, which of the following is a characteristic pathological finding?

• A. Pannus formation
• B. Eburnation of subchondral bone
• C. Synovial hyperplasia
• D. Immune complex deposition

Which of the following serum markers is most commonly elevated in Paget’s
disease of bone?

• A. Serum calcium
• B. Serum phosphorus
• C. Alkaline phosphatase
D. Parathyroid hormone

A 30-year-old male with rheumatoid arthritis is found to have a rheumatoid nodule on biopsy. What is the characteristic histologic finding?

• A. Central area of necrosis surrounded by palisading macrophages
• B. Caseous necrosis with granulomas
• C. Multinucleated giant cells with fibroblastic proliferation
• D. Fibrosis with lymphocytic infiltration

That's all for today :). See you with a short live session by weekend with this week's topic.

Workbook for today's class !! (link to 2023 batch is there in the PDF)

Link for todays class
https://www.youtube.com/live/4EqzPcV8xM0

Work book for today;s RRR

A simple IBQ (PYQ) - Comment on your answer !

https://www.instagram.com/reel/DA0px_joqA7/?utm_source=ig_web_copy_link