стройством существенно снижена активность фермента цитратсинтазы.

#митохондрии #кальций #кальциевые_каналы #шизофрения #биполярное_расстройство

Bar-Yosef, T., Hussein, W., Yitzhaki, O., Damri, O., Givon, L., Marom, C., Gurman, V., Levine, J., Bersudsky, Y., Agam, G., & Ben-Shachar, D. (2020). Mitochondrial function parameters as a tool for tailored drug treatment of an individual with psychosis: a proof of concept study. Scientific reports, 10(1), 12258. https://doi.org/10.1038/s41598-020-69207-4

Machado, A. K., Pan, A. Y., da Silva, T. M., Duong, A., & Andreazza, A. C. (2016). Upstream Pathways Controlling Mitochondrial Function in Major Psychosis: A Focus on Bipolar Disorder. Canadian journal of psychiatry. Revue canadienne de psychiatrie, 61(8), 446–456. https://doi.org/10.1177/0706743716648297

Bergman, O., & Ben-Shachar, D. (2016). Mitochondrial Oxidative Phosphorylation System (OXPHOS) Deficits in Schizophrenia: Possible Interactions with Cellular Processes. Canadian journal of psychiatry. Revue canadienne de psychiatrie, 61(8), 457–469. https://doi.org/10.1177/0706743716648290

Kato T. Neurobiological basis of bipolar disorder: Mitochondrial dysfunction hypothesis and beyond. Schizophr Res. 2017 Sep;187:62-66. doi: 10.1016/j.schres.2016.10.037. Epub 2016 Nov 10. PMID: 27839913.

M. ĽUPTÁK , J. HROUDOVÁ. Important Role of Mitochondria and the Effect of Mood Stabilizers on Mitochondrial Function.
Physiol. Res. 68 (Suppl. 1): S3-S15, 2019
https://doi.org/10.33549/physiolres.934324

Cikánková T, Fišar Z, Hroudová J. In vitro effects of antidepressants and mood-stabilizing drugs on cell energy metabolism. Naunyn Schmiedebergs Arch Pharmacol. 2020 May;393(5):797-811. doi: 10.1007/s00210-019-01791-3. Epub 2019 Dec 19. PMID: 31858154.

Lundberg, M., Millischer, V., Backlund, L., Martinsson, L., Stenvinkel, P., Sellgren, C. M., Lavebratt, C., & Schalling, M. (2020). Lithium and the Interplay Between Telomeres and Mitochondria in Bipolar Disorder. Frontiers in psychiatry, 11, 586083. https://doi.org/10.3389/fpsyt.2020.586083

Zvěřová, M., Hroudová, J., Fišar, Z., Hansíková, H., Kališová, L., Kitzlerová, E., Lambertová, A., & Raboch, J. (2019). Disturbances of mitochondrial parameters to distinguish patients with depressive episode of bipolar disorder and major depressive disorder. Neuropsychiatric disease and treatment, 15, 233–240. https://doi.org/10.2147/NDT.S188964

Bolzetta, Francesco & Veronese, Nicola & Stubbs, Brendon & Noale, Marianna & Vaona, Alberto & Demurtas, Jacopo & Celotto, Stefano & Cacco, Chiara & Cester, Alberto & Caruso, Maria & Reddavide, Rosa & Notarnicola, Maria & Maggi, Stefania & Koyanagi, Ai & Fornaro, Michele & Firth, Joseph & Smith, Lee & Solmi, Marco. (2019). The Relationship between Dietary Vitamin K and Depressive Symptoms in Late Adulthood: A Cross-Sectional Analysis from a Large Cohort Study. Nutrients. 11. 10.3390/nu11040787.

5. У людей с хронической почечной недостаточностью субклинический дефицит витамина К

Cozzolino, M., Mangano, M., Galassi, A., Ciceri, P., Messa, P., & Nigwekar, S. (2019). Vitamin K in Chronic Kidney Disease. Nutrients, 11(1), 168. https://doi.org/10.3390/nu11010168

6. На животных и ин витро было показано, что витамин К1 подавляет образование кристаллов в ткани почек.

Li Y, Lu X, Yang B, Mao J, Jiang S, Yu D, Pan J, Cai T, Yasui T, Gao B: Vitamin K1 Inhibition of Renal Crystal Formation through Matrix Gla Protein in the Kidney. Kidney Blood Press Res 2019;44:1392-1403. doi: 10.1159/000503300

#мочевая_кислота #витамин_д #витамин_к #камни_в_почках #кальций #паратгормон