#Obesity Has a Stronger Relationship with Colorectal #Cancer in Postmenopausal Women Than Premenopausal Women
https://2medical.news/2020/09/09/obesity-has-a-stronger-relationship-with-colorectal-cancer-in-postmenopausal-women-than-premenopausal-women/
Background: To examine the relationship between obesity measured by waist circumference (WC) and body mass index (BMI) and the incidence of colorectal cancer (CRC) in premenopausal and postmenopausal women. Methods: A total of 1,418,180 premenopausal and 4,854,187 postmenopausal women without cancer at baseline and aged over 40 were identified using the Korean National Health Insurance System Cohort during 2009-2014. The hazard ratio (HR) for CRC …
https://2medical.news/2020/09/09/obesity-has-a-stronger-relationship-with-colorectal-cancer-in-postmenopausal-women-than-premenopausal-women/
Background: To examine the relationship between obesity measured by waist circumference (WC) and body mass index (BMI) and the incidence of colorectal cancer (CRC) in premenopausal and postmenopausal women. Methods: A total of 1,418,180 premenopausal and 4,854,187 postmenopausal women without cancer at baseline and aged over 40 were identified using the Korean National Health Insurance System Cohort during 2009-2014. The hazard ratio (HR) for CRC …
Effects of Time-Restricted Eating on #Weight Loss and Other Metabolic Parameters in Women and Men With Overweight and #Obesity
https://2medical.news/2020/10/02/effects-of-time-restricted-eating-on-weight-loss-and-other-metabolic-parameters-in-women-and-men-with-overweight-and-obesity/
.. Participants were randomized such that the consistent meal timing (CMT) group was instructed to eat 3 structured meals per day, and the time-restricted eating (TRE) group was instructed to eat ad libitum from 12:00 pm until 8:00 pm and completely abstain from caloric intake from 8:00 pm until 12:00 pm the following day. Design, Setting, and Participants This 12-week randomized clinical trial including men …
https://2medical.news/2020/10/02/effects-of-time-restricted-eating-on-weight-loss-and-other-metabolic-parameters-in-women-and-men-with-overweight-and-obesity/
.. Participants were randomized such that the consistent meal timing (CMT) group was instructed to eat 3 structured meals per day, and the time-restricted eating (TRE) group was instructed to eat ad libitum from 12:00 pm until 8:00 pm and completely abstain from caloric intake from 8:00 pm until 12:00 pm the following day. Design, Setting, and Participants This 12-week randomized clinical trial including men …
A Time Frame for Testing Negative for SARS- #COV2 in People with #Obesity
https://2medical.news/2020/11/07/a-time-frame-for-testing-negative-for-sars-cov2-in-people-with-obesity/
Objective: Obesity is a major risk factor for becoming seriously ill with the 2019 novel coronavirus (COVID-19). One difficulty faced by clinicians and by patients is the unknown time frame of hospitalization until discharge of symptomatic patients. Methods: We followed 34 patients with laboratory-confirmed COVID-19 infection who recovered fromthe infection. All diagnoses were given using semi-quantitative RT-PCR on nasopharyngeal swabs. Envelope protein gene (E), RNA-dependent …
https://2medical.news/2020/11/07/a-time-frame-for-testing-negative-for-sars-cov2-in-people-with-obesity/
Objective: Obesity is a major risk factor for becoming seriously ill with the 2019 novel coronavirus (COVID-19). One difficulty faced by clinicians and by patients is the unknown time frame of hospitalization until discharge of symptomatic patients. Methods: We followed 34 patients with laboratory-confirmed COVID-19 infection who recovered fromthe infection. All diagnoses were given using semi-quantitative RT-PCR on nasopharyngeal swabs. Envelope protein gene (E), RNA-dependent …
#Avocado Consumption Alters Gastrointestinal #Bacteria Abundance and Microbial Metabolite Concentrations among Adults with Overweight or #Obesity: A Randomized Controlled Trial
https://2medical.news/2021/01/02/avocado-consumption-alters-gastrointestinal-bacteria-abundance-and-microbial-metabolite-concentrations-among-adults-with-overweight-or-obesity-a-randomized-controlled-trial/
Avocados are rich in dietary fiber and monounsaturated fatty acids (MUFAs), nutrients that have been independently connected to metabolic health benefits and the gastrointestinal microbiota. Objectives We aimed to evaluate the impact of avocado consumption on the gastrointestinal microbiota and microbial metabolites, secondary outcomes of the Persea americana for Total Health (PATH) study, and conduct exploratory analyses to assess relations between the fecal microbiota, fecal …
https://2medical.news/2021/01/02/avocado-consumption-alters-gastrointestinal-bacteria-abundance-and-microbial-metabolite-concentrations-among-adults-with-overweight-or-obesity-a-randomized-controlled-trial/
Avocados are rich in dietary fiber and monounsaturated fatty acids (MUFAs), nutrients that have been independently connected to metabolic health benefits and the gastrointestinal microbiota. Objectives We aimed to evaluate the impact of avocado consumption on the gastrointestinal microbiota and microbial metabolites, secondary outcomes of the Persea americana for Total Health (PATH) study, and conduct exploratory analyses to assess relations between the fecal microbiota, fecal …
#Adipose saturation reduces #lipotoxic systemic inflammation and explains the #obesity paradox
https://2medical.news/2021/02/05/adipose-saturation-reduces-lipotoxic-systemic-inflammation-and-explains-the-obesity-paradox/
Obesity sometimes seems protective in disease. This obesity paradox is predominantly described in reports from the Western Hemisphere during acute illnesses. Since adipose triglyceride composition corresponds to long-term dietary patterns, we performed a meta-analysis modeling the effect of obesity on severity of acute pancreatitis, in the context of dietary patterns of the countries from which the studies originated. Increased severity was noted in leaner populations …
https://2medical.news/2021/02/05/adipose-saturation-reduces-lipotoxic-systemic-inflammation-and-explains-the-obesity-paradox/
Obesity sometimes seems protective in disease. This obesity paradox is predominantly described in reports from the Western Hemisphere during acute illnesses. Since adipose triglyceride composition corresponds to long-term dietary patterns, we performed a meta-analysis modeling the effect of obesity on severity of acute pancreatitis, in the context of dietary patterns of the countries from which the studies originated. Increased severity was noted in leaner populations …
Once-Weekly #Semaglutide in Adults with Overweight or #Obesity
https://2medical.news/2021/02/13/once-weekly-semaglutide-in-adults-with-overweight-or-obesity/
Obesity is a global health challenge with few pharmacologic options. Whether adults with obesity can achieve weight loss with once-weekly semaglutide at a dose of 2.4 mg as an adjunct to lifestyle intervention has not been confirmed. METHODS In this double-blind trial, we enrolled 1961 adults with a body-mass index (the weight in kilograms divided by the square of the height in meters) of 30 …
https://2medical.news/2021/02/13/once-weekly-semaglutide-in-adults-with-overweight-or-obesity/
Obesity is a global health challenge with few pharmacologic options. Whether adults with obesity can achieve weight loss with once-weekly semaglutide at a dose of 2.4 mg as an adjunct to lifestyle intervention has not been confirmed. METHODS In this double-blind trial, we enrolled 1961 adults with a body-mass index (the weight in kilograms divided by the square of the height in meters) of 30 …
Association of #Gastric Bypass Surgery With Risk of Developing #Diabetic #Retinopathy Among Patients With #Obesity and Type 2 Diabetes in Sweden
https://2medical.news/2021/02/21/association-of-gastric-bypass-surgery-with-risk-of-developing-diabetic-retinopathy-among-patients-with-obesity-and-type-2-diabetes-in-sweden/
Knowledge of the incidence and progression of diabetic retinopathy (DR) after gastric bypass surgery (GBP) in patients with obesity and diabetes could guide the management of these patients. Objective To investigate the incidence of diabetic ocular complications in patients with type 2 diabetes after GBP compared with the incidence of diabetic ocular complications in a matched cohort of patients with obesity and diabetes who have …
https://2medical.news/2021/02/21/association-of-gastric-bypass-surgery-with-risk-of-developing-diabetic-retinopathy-among-patients-with-obesity-and-type-2-diabetes-in-sweden/
Knowledge of the incidence and progression of diabetic retinopathy (DR) after gastric bypass surgery (GBP) in patients with obesity and diabetes could guide the management of these patients. Objective To investigate the incidence of diabetic ocular complications in patients with type 2 diabetes after GBP compared with the incidence of diabetic ocular complications in a matched cohort of patients with obesity and diabetes who have …
Self- Monitoring via Digital Health in #Weight Loss Interventions: A Systematic Review Among Adults with Overweight or #Obesity
https://2medical.news/2021/03/01/self-monitoring-via-digital-health-in-weight-loss-interventions-a-systematic-review-among-adults-with-overweight-or-obesity/
Objective: Self- monitoring is a core component of behavioral obesity treatment, but it is unknown how digital health has been used for self- monitoring, what engagement rates are achieved in these interven-tions, and how self- monitoring and weight loss are related. Methods: This systematic review examined digital self- monitoring in behavioral weight loss interventions among adults with overweight or obesity. Six databases (PubMed, Embase, Scopus, …
https://2medical.news/2021/03/01/self-monitoring-via-digital-health-in-weight-loss-interventions-a-systematic-review-among-adults-with-overweight-or-obesity/
Objective: Self- monitoring is a core component of behavioral obesity treatment, but it is unknown how digital health has been used for self- monitoring, what engagement rates are achieved in these interven-tions, and how self- monitoring and weight loss are related. Methods: This systematic review examined digital self- monitoring in behavioral weight loss interventions among adults with overweight or obesity. Six databases (PubMed, Embase, Scopus, …
Association between #obesity with pattern and length of #menstrual cycle: The role of metabolic and hormonal markers
https://2medical.news/2021/03/03/association-between-obesity-with-pattern-and-length-of-menstrual-cycle-the-role-of-metabolic-and-hormonal-markers/
To evaluate in a sample of Chilean adult women, the association between adiposity markers with pattern and length of the menstrual cycle, assessing the influence of metabolic markers and hormones in this relationship. Study design We conducted a cross-sectional study involving 401 premenopausal women belonging to the DERCAM study (Determinants of Breast Cancer Risk) from Santiago, Chile. The menstrual cycle pattern was defined as regular …
https://2medical.news/2021/03/03/association-between-obesity-with-pattern-and-length-of-menstrual-cycle-the-role-of-metabolic-and-hormonal-markers/
To evaluate in a sample of Chilean adult women, the association between adiposity markers with pattern and length of the menstrual cycle, assessing the influence of metabolic markers and hormones in this relationship. Study design We conducted a cross-sectional study involving 401 premenopausal women belonging to the DERCAM study (Determinants of Breast Cancer Risk) from Santiago, Chile. The menstrual cycle pattern was defined as regular …
#Semaglutide 2·4 mg once a week in adults with #overweight or #obesity, and type 2 diabetes (STEP 2): a randomised, double-blind, double-dummy, placebo-controlled, phase 3 trial
https://2medical.news/2021/03/24/semaglutide-2%C2%B74-mg-once-a-week-in-adults-with-overweight-or-obesity-and-type-2-diabetes-step-2-a-randomised-double-blind-double-dummy-placebo-controlled-phase-3-trial/
Background This trial assessed the efficacy and safety of the GLP-1 analogue once a week subcutaneous semaglutide 2·4 mg versus semaglutide 1·0 mg (the dose approved for diabetes treatment) and placebo for weight management in adults with overweight or obesity, and type 2 diabetes. Methods This double-blind, double-dummy, phase 3, superiority study enrolled adults with a body-mass index of at least 27 kg/m2 and glycated …
https://2medical.news/2021/03/24/semaglutide-2%C2%B74-mg-once-a-week-in-adults-with-overweight-or-obesity-and-type-2-diabetes-step-2-a-randomised-double-blind-double-dummy-placebo-controlled-phase-3-trial/
Background This trial assessed the efficacy and safety of the GLP-1 analogue once a week subcutaneous semaglutide 2·4 mg versus semaglutide 1·0 mg (the dose approved for diabetes treatment) and placebo for weight management in adults with overweight or obesity, and type 2 diabetes. Methods This double-blind, double-dummy, phase 3, superiority study enrolled adults with a body-mass index of at least 27 kg/m2 and glycated …