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Aldo Lorenzetti M.D, Internal Medicine & Hepatology, Milano - SIMEDET Delegate
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#Ecigarettes can emit #formaldehyde at high levels under conditions that have been reported to be non-averse to users


https://www.nature.com/articles/s41598-018-25907-6


E-cigarette aerosol emission studies typically focus on benchmarking toxicant levels versus those of cigarettes. However, such studies do not fully account for the distinct chemical makeup of e-liquids and their unique properties. These approaches often conclude that there are fewer and lower levels of toxins produced by e-cigarettes than by cigarettes. In 2015, we reported the discovery of new hemiacetals derived from the reaction of formaldehyde and the e-liquid solvents. The main finding was that they constituted a significant proportion of potentially undetected formaldehyde. Moreover, unlike gaseous formaldehyde, the hemiacetals reside in the aerosol particulate phase, and thus are capable of delivering formaldehyde more deeply into the lungs. However, the findings were criticized by those claiming that some of the results were obtained under conditions that are averse to vapers. A “reinvestigation” of our study was recently published addressing this latter issue. However, this reinvestigation ignored major details, including no mention of the formaldehyde hemiacetals. Herein, we isolated both gaseous formaldehyde and formaldehyde hemiacetals at an intermediate power level claimed, in the “reinvestigation”, to be relevant to “non-averse,” “normal” usage. The results were that both gaseous formaldehyde and formaldehyde from hemiacetals were produced at levels above OSHA workplace limits
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CDC, FDA, States Continue to Investigate Severe #Pulmonary Disease Among People Who Use #Ecigarettes

https://www.cdc.gov/media/releases/2019/s0821-cdc-fda-states-e-cigarettes.html

August 23, 2019: As of 5:00 p.m., August 22, 193 potential cases of severe lung illness associated with e-cigarette product use had been reported by 22 states (CA, CT, IL, IN, IA, MN, MI, NC, NJ, NM, NY, PA, TX, UT, WI, and additional states pending verification). These were reported between June 28th and August 20th of this year.

CDC is providing consultation to state health departments about a cluster of pulmonary illnesses possibly related to e-cigarette product use, or “vaping,” primarily among adolescents and young adults

CDC and states have not identified a cause, but all reported cases have e-cigarette product use or “vaping.”

Available evidence does not suggest that an infectious disease is the principal cause of the illness.

Investigators have not identified any specific product or compound that is linked to all cases...