Increased infectiousness of coronavirus variants.
A team of researchers at Duke University has combined concepts from structural biology with computation to show that multiple mutations on the SARS-CoV-2 spike protein independently create variants that are both more transmissible and resistant to antibodies.
The mechanisms are explained in Science: https://science.sciencemag.org/content/early/2021/06/23/science.abi6226
#sciencenews #biosciences #covid
A team of researchers at Duke University has combined concepts from structural biology with computation to show that multiple mutations on the SARS-CoV-2 spike protein independently create variants that are both more transmissible and resistant to antibodies.
The mechanisms are explained in Science: https://science.sciencemag.org/content/early/2021/06/23/science.abi6226
#sciencenews #biosciences #covid
Science
Effect of natural mutations of SARS-CoV-2 on spike structure, conformation, and antigenicity
SARS-CoV-2 variants with multiple spike mutations enable increased transmission and antibody resistance. Here, we combine cryo-EM, binding and computational analyses to study variant spikes, including one that was involved in transmission between minks and…