3D printed diagnostic tools.
Lateral flow testing is widely used for pregnancy tests and more recently for mass coronavirus testing. A team working at KU Leuven has developed a new 3D printing technique using porous polymers to produce advanced diagnostic tests quickly, cheaply, and easily.
The method can be seen in action at: https://www.youtube.com/watch?v=qRVa7X_LnV4
#sciencenews #healthcare #medicine #polymers
Lateral flow testing is widely used for pregnancy tests and more recently for mass coronavirus testing. A team working at KU Leuven has developed a new 3D printing technique using porous polymers to produce advanced diagnostic tests quickly, cheaply, and easily.
The method can be seen in action at: https://www.youtube.com/watch?v=qRVa7X_LnV4
#sciencenews #healthcare #medicine #polymers
YouTube
3D printing technique for lateral flow diagnostics
A 3D printing technique developed at the Ameloot Group (KU Leuven) promises to bring the kind of rapid diagnosis seen with lateral flow tests for Covid-19 to other medical conditions. The goal is to produce a wide range of sophisticated diagnostic tests that…
A health boost from nature.
Access to nature increases city-dwellers’ physical activity and overall health. Researchers from Stanford University explain that parks, lakes, trees and other urban green spaces are a necessary part of creating more healthy, equitable, and sustainable cities.
Learn more from their article in PNAS: https://www.pnas.org/content/118/22/e2018472118
#sciencenews #medicine #healthcare #health
Access to nature increases city-dwellers’ physical activity and overall health. Researchers from Stanford University explain that parks, lakes, trees and other urban green spaces are a necessary part of creating more healthy, equitable, and sustainable cities.
Learn more from their article in PNAS: https://www.pnas.org/content/118/22/e2018472118
#sciencenews #medicine #healthcare #health
PNAS
An ecosystem service perspective on urban nature, physical activity, and health
Nature underpins human well-being in critical ways, especially in health. Nature provides pollination of nutritious crops, purification of drinking water, protection from floods, and climate security, among other well-studied health benefits. A crucial, yet…
Ending childhood respiratory infections.
Human parainfluenza viruses are the leading cause of childhood respiratory infections. There are currently no available vaccines for the most prevalent of these viruses. Research from the University of Wisconsin shows that engineering suitable short chunks of protein can prevent the attachment of human parainfluenza viruses to cells.
The work has recently been published in JACS: https://pubs.acs.org/doi/10.1021/jacs.1c01565
#sciencenews #healthcare #health #medicine #vaccine
Human parainfluenza viruses are the leading cause of childhood respiratory infections. There are currently no available vaccines for the most prevalent of these viruses. Research from the University of Wisconsin shows that engineering suitable short chunks of protein can prevent the attachment of human parainfluenza viruses to cells.
The work has recently been published in JACS: https://pubs.acs.org/doi/10.1021/jacs.1c01565
#sciencenews #healthcare #health #medicine #vaccine
ACS Publications
Engineering Protease-Resistant Peptides to Inhibit Human Parainfluenza Viral Respiratory Infection
The lower respiratory tract infections affecting children worldwide are in large part caused by the parainfluenza viruses (HPIVs), particularly HPIV3, along with human metapneumovirus and respiratory syncytial virus, enveloped negative-strand RNA viruses.…
Diagnosing prostate cancer with light.
Prostate cancer is the second most common cancer globally in men, but rapid and accurate screening remains a challenge. Researchers from Chernivtsi National University & University of Oulu demonstrate a diagnostic method using polarized light that can quickly analyze prostate tissue samples for signs of cancer.
The results are published in Scientific Reports: https://www.nature.com/articles/s41598-021-83986-4
#sciencenews #medicine #healthcare #health #light
Prostate cancer is the second most common cancer globally in men, but rapid and accurate screening remains a challenge. Researchers from Chernivtsi National University & University of Oulu demonstrate a diagnostic method using polarized light that can quickly analyze prostate tissue samples for signs of cancer.
The results are published in Scientific Reports: https://www.nature.com/articles/s41598-021-83986-4
#sciencenews #medicine #healthcare #health #light
Nature
3D Mueller matrix mapping of layered distributions of depolarisation degree for analysis of prostate adenoma and carcinoma diffuse…
Scientific Reports - <ArticleTitle Language="En" OutputMedium="All" xml:lang="en">3D Mueller matrix mapping of layered...
Stem cell tuning.
Researchers from Tokyo Metropolitan University have quantified how mesenchymal stem cells respond to the mechanical stiffness of their environments. Specific proteins can be localized in the cell nucleus depending on the stiffness. Their findings will help scientists control the state of stem cells in medical treatments.
Their work has been published in Analytical Sciences: https://doi.org/10.2116/analsci.20SCP02
#sciencenews #biology #genetics #medicine
Researchers from Tokyo Metropolitan University have quantified how mesenchymal stem cells respond to the mechanical stiffness of their environments. Specific proteins can be localized in the cell nucleus depending on the stiffness. Their findings will help scientists control the state of stem cells in medical treatments.
Their work has been published in Analytical Sciences: https://doi.org/10.2116/analsci.20SCP02
#sciencenews #biology #genetics #medicine
J-STAGE
Designing Elastic Modulus of Cell Culture Substrate to Regulate YAP and RUNX2 Localization for Controlling Differentiation of Human…
To establish a guideline for the design of cell culture substrates to control human mesenchymal stem cell (MSC) differentiation, we quantitatively cha …
Viruses fighting cancer.
Researchers at the Luxembourg Institute of Health have developed a cancer-destroying virus that binds to laminins on the surface of cancer cells to gain entry to the cell before ultimately killing it. The viruses hold significant potential for deployment in targeted cancer therapies.
The work has recently been published in Nature Communications: http://dx.doi.org/10.1038/s41467-021-24034-7
#sciencenews #medicine #health
Researchers at the Luxembourg Institute of Health have developed a cancer-destroying virus that binds to laminins on the surface of cancer cells to gain entry to the cell before ultimately killing it. The viruses hold significant potential for deployment in targeted cancer therapies.
The work has recently been published in Nature Communications: http://dx.doi.org/10.1038/s41467-021-24034-7
#sciencenews #medicine #health
Nature
Oncolytic H-1 parvovirus binds to sialic acid on laminins for cell attachment and entry
Nature Communications - Rat H-1 parvovirus (H-1PV) is in clinical development for oncolytic therapy. Here, Kulkarni et al. identify LAMC1 as a modulator of H-1PV cell attachment and entry and find...
Cancer testing from blood.
A microfilter device that can easily separate and capture trace amounts of cancer cells in blood has been developed by a Kumamoto University research group. The palm-sized device is being used to develop new cancer diagnostic technologies, detecting even at concentrations of just 5 cancer cells per millilitre.
The research is reported in Talanta:
https://www.sciencedirect.com/science/article/abs/pii/S0039914021001600?via%3Dihub
#sciencenews #cancer #medicine
A microfilter device that can easily separate and capture trace amounts of cancer cells in blood has been developed by a Kumamoto University research group. The palm-sized device is being used to develop new cancer diagnostic technologies, detecting even at concentrations of just 5 cancer cells per millilitre.
The research is reported in Talanta:
https://www.sciencedirect.com/science/article/abs/pii/S0039914021001600?via%3Dihub
#sciencenews #cancer #medicine
Sciencedirect
Detection of cancer cells in whole blood using a dynamic deformable microfilter and a nucleic acid aptamer
Cancer cell count in the blood of cancer patients is extremely low. If these cells are easily detectable, cancer diagnosis may be possible by simply u…
Mefloquine – fighting coronavirus.
Scientists from Tokyo University of Science have identified the anti-malarial drug mefloquine as being effective against SARS-CoV-2. They show that the drug effectively limits the entry of the virus into the cells.
Learn about their insight in Frontiers in Microbiology: https://doi.org/10.3389/fmicb.2021.651403
#sciencenews #coronavirus #healthcare #medicine
Scientists from Tokyo University of Science have identified the anti-malarial drug mefloquine as being effective against SARS-CoV-2. They show that the drug effectively limits the entry of the virus into the cells.
Learn about their insight in Frontiers in Microbiology: https://doi.org/10.3389/fmicb.2021.651403
#sciencenews #coronavirus #healthcare #medicine
Frontiers
Mefloquine, a Potent Anti-severe Acute Respiratory Syndrome-Related Coronavirus 2 (SARS-CoV-2) Drug as an Entry Inhibitor in vitro
Coronavirus disease 2019 (COVID-19) has caused serious public health, social, and economic damage worldwide and effective drugs that prevent or cure COVID-19 are urgently needed. Approved drugs including Hydroxychloroquine, Remdesivir or Interferon were reported…
How Covid-19 affects the blood.
Researchers at the Max-Planck-Zentrum für Physik und Medizin showed that Covid-19 significantly changes the size and stiffness of red and white blood cells over periods of months. These results could explain why some people continue to experience symptoms long after the infection.
Their work is published in the Biophysical Journal: https://www.cell.com/biophysj/fulltext/S0006-3495(21)00454-9
#sciencenews #medicine #immunology
Researchers at the Max-Planck-Zentrum für Physik und Medizin showed that Covid-19 significantly changes the size and stiffness of red and white blood cells over periods of months. These results could explain why some people continue to experience symptoms long after the infection.
Their work is published in the Biophysical Journal: https://www.cell.com/biophysj/fulltext/S0006-3495(21)00454-9
#sciencenews #medicine #immunology
Replacing endoscopy.
A study from the University of Houston reports a step forward in diagnosing intestinal diseases, including colorectal cancer, ulcerative colitis and Crohn's disease using stool proteins. The non-invasive test could lead to the replacement of endoscopy as the diagnostic tool of choice.
The study is published in Nature Communications: https://www.nature.com/articles/s41467-021-24235-0
#sciencenews #medicine
A study from the University of Houston reports a step forward in diagnosing intestinal diseases, including colorectal cancer, ulcerative colitis and Crohn's disease using stool proteins. The non-invasive test could lead to the replacement of endoscopy as the diagnostic tool of choice.
The study is published in Nature Communications: https://www.nature.com/articles/s41467-021-24235-0
#sciencenews #medicine
Nature
Predicting disease course in ulcerative colitis using stool proteins identified through an aptamer-based screen
Nature Communications - Stool biomarkers hold promise for monitoring disease activity and predicting clinical course in inflammatory bowel disease (IBD) as they originate from the inflamed tissue....
Kidney treatments.
Medics in Indiana University School of Medicine have investigated alternative ways to treat kidney infections, knowing that antibiotic resistance is an increasing problem. They examined methods to trigger the kidneys’ own internal processes to fight the infections.
Their findings are published in the Nature Communications: http://dx.doi.org/10.1038/s41467-021-22672-5
#sciencenews #medicine
Medics in Indiana University School of Medicine have investigated alternative ways to treat kidney infections, knowing that antibiotic resistance is an increasing problem. They examined methods to trigger the kidneys’ own internal processes to fight the infections.
Their findings are published in the Nature Communications: http://dx.doi.org/10.1038/s41467-021-22672-5
#sciencenews #medicine
Nature
Kidney intercalated cells are phagocytic and acidify internalized uropathogenic Escherichia coli
Nature Communications - Kidney intercalated cells are involved in acid-base homeostasis in the kidneys. Here, the authors use single cell transcriptomics and find that interalated cells exhibit a...