How Fat Embolism Causes ARDS
Mechanical Blockage: Fat globules from bone marrow or adipose tissue enter torn blood vessels and lodge in the small capillaries of the lungs.
Inflammatory Cascade: Trapped fat breaks down into toxic free fatty acids, triggering a strong local and systemic inflammatory response.
Increased Permobility: Inflammatory mediators damage the capillary walls, leading to high-permeability pulmonary edema, hemorrhage, and diffuse alveolar injury that match ARDS.
Mechanical Blockage: Fat globules from bone marrow or adipose tissue enter torn blood vessels and lodge in the small capillaries of the lungs.
Inflammatory Cascade: Trapped fat breaks down into toxic free fatty acids, triggering a strong local and systemic inflammatory response.
Increased Permobility: Inflammatory mediators damage the capillary walls, leading to high-permeability pulmonary edema, hemorrhage, and diffuse alveolar injury that match ARDS.
🤯1