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Thrombotic pulmonary embolism
vs Fat pulmonary embolim


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How does fat embolism affect the respiratory system? 🫁

It does not obstruct the main vessels; instead, it distributes to the tiny vessels throughout the lung tissue.
How Fat Embolism Causes ARDS

Mechanical Blockage: Fat globules from bone marrow or adipose tissue enter torn blood vessels and lodge in the small capillaries of the lungs.

Inflammatory Cascade: Trapped fat breaks down into toxic free fatty acids, triggering a strong local and systemic inflammatory response.

Increased Permobility: Inflammatory mediators damage the capillary walls, leading to high-permeability pulmonary edema, hemorrhage, and diffuse alveolar injury that match ARDS.
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Updated ESC 2026
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