هذا سلايدات المحاضرة الثانية التي تم الحصول عليها بتحوي تعليقات الدكتورة منية على السلايدات وكل حالة مرضية مع diagnosis and treatment
#باثو

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ملخص لجميع محاضرات كلام الدكتورة ٲسماء على شكل short notes

A 34-year-old accountant presents to the emergency room because of headache and fever of 3 days’ duration. The day before admission his wife noted mild confusion and irritability. Lumbar puncture revealed an opening pressure of 300 mm, 200 red blood cells, 90% of the WBCs whichare lymphocytes, sugar of 85 mg/dL (concomitant blood sugar of 110mg/dL), and protein of 65 mg/dL. Bacteriologic smears (and ultimately alsothe bacterial cultures) were negative, as were India ink preparations. All latex particle agglutination tests for fungal and bacterial capsules done onthe patient’s CSF were also negative. The patient’s condition did notimprove despite appropriate therapy, and he died 10 days after hospitalization.


0. What is the most likely diagnosis?
Answer: Herpes simplex encephalitis

0. What is the virus’s shape?
Answer: Icosahedral with nuclear membrane envelope.

0. Where within the cell does the virus replicate?
Answer: Nucleus for both DNA synthesis and assembly.

0. What other members belong to the same family?
Answers: EBV, Varicella-Zoster, Cytomegalovirus.

Virology#

65-year-old retired male police officer reports to an emergent care facility complaining of fever, sore throat, shortness of breath, dry cough, and generalized muscle aches and pains. On examination the patient is pale, tachycardic, and tachypneic. His conjunctivae are congested and rales and wheezes are heard over both lung fields. A chest radiograph shows diffuse bilateral infiltrates and a hemagglutination inhibition
antibody test is positive at high titer.


0. What is your diagnosis?
Answer: Influenza

0. What drugs are available to treat this disease?
Answer: Amantadine/rimantadine (inhibit uncoating)
Zanamivir/oseltamivir (inhibit neuraminidase)

0. To what viral family does it belong?
Answer: Orthomyxovirus
0. Where in the cell does it replicate?
Answer: Cytoplasm and nucleus

0. What vaccine might have prevented this?
Answer: Killed, H3N2, H1N1 plus one strain of Influenza B

0. What attribute of the agent causes pandemics?
Answer: Segmented genome can be reassorted, causing genetic shift.

Virology#

🚑young man became ill with a sore throat and swollen tonsils, marked fatigue, cervical adenopathy, a palpable spleen, and a pruritic
erythematous rash that started after self-administration of ampicillin.

🧫 What is the most likely disease? What are the most common laboratory
diagnostic tests? What does the antibody test measure?
Answer: Infectious mononucleosis; monospot test (measures heterophile
antibody which is not specific to EBV antigen) plus CBC.

🧫 What type of cells are the Downey type II cells?
Answer: T lymphocytes. (Reactive cells, not infected.)


💊What cells does the virus infect? Through what receptor does the lymphocytic infection begin?
Answer: EBV infects epithelial cells and B lymphocytes, whose receptor is
CD21 = CR2.
Virology#

Test forms
مايخص دفعة 34 ؛ نماذج من السنوات السابقة .. بسم الله ✨
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🧟‍♂27-year-old attorney is hospitalized. He was in excellent health until two
days earlier when he noted malaise, fatigability, and profound anorexia.He remembers approximately 6–8 weeks ago receiving a tattoo while vacationing in the Caribbean.

🧫 How would you confirm your clinical diagnosis?
Answer: HBsAg and IgM to HbcAg.

♋What is meant by the “window”?
Answer: A time period between the end of the detectable presence of
HBsAg and the beginning of the production of HBsAb. HBcAb and HBeAb are present.

☣What antigen’s persistence beyond 6 months post-infection is indicative
that the patient is entering a carrier state?
Answer: HBsAg past 6 months.

🌬What antigen correlates with viral production?
Answer: HBeAg.

🦠 Does the virus carry a virion associated polymerase? If so, what kind?
Answer: Yes, RNA-dependent DNA polymerase (Hepatitis B replicates
through an 🧬RNA intermediate).

Virology#

نقلا عن الدكتوره اسماء
بلغي زملائك اختباركم الاحد ان شاء الله

من الساعة ١٠ الكل يكون متواجد مجموعتين بختبرهم من ١٠ الى ١١ ان شاء الله ومجموعتين من ١١ الى ١٢

الاختبار كما اتفقنا كل الHelminth
تعرف فقط
اما ال Protozoa
بيكون تعرف ع الصورة وسؤال عليها

بالتوفيق

طبعا الاختبار بيكون 10 اسئله
من 6 الى 7 اسئله تعرف على الشريحه من حق ترم ثاني .
وثلاثه الى 4 اسئلة من حق ترم اول وكلهن بيكونين صور تعرف عليها وسؤال اخر مثل اختبار ترم اول .

الاختبار عليه تقريبا 30 درجه.

شكرا د/راقية

💐Rational Steps of prescription of drugs :

1- Make diagnosis .
2- Consider Pathophysiology of the disease .
3- Therapy Objective .
4- Drug of Choice .
5- Dosage Regimen .
6- Devise a plan of Drug monitoring.
7- Patient Education.

#معمل_فارما

ملخص معمل الميكرو٢👇👇
تلخيص :-
د/تسامي سعيد
#اللجنة_العلمية

Micro lab 3
Serological test
👇👇

تلخيص د/نجيبة العريف

معمل مايكرو4
للدكتور: بسام
اعداد : نجيبة العريف

#اللجنة_العلمية

كتاب الدكتور ممدوح
من الشابتر الرابع للسابع

#معمل_فارما