Surgical notes
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๐Ÿค• common skin rashes :-

1- macule : small ,flat
2- papule : small ,raised ( solid)
Maculopapule Both^
3- vesicle : small , elevated ( with clear fluid)
4- pastule : vesicle filled with pus
5- Nodule: large , raised, Solid


๐Ÿค• Differences between Droplets / Airborne :-

Droplets : Large >5 microns
Surface contamination
Removed by hand wash

Airborne:- smaller ( Droplet nuclei )
<5 microns
Still in the air ( more dangerous)

#ููŠุฑูˆุณุงุช
#ู…ุงูŠูƒุฑูˆ
๐Ÿค”For EBV :

Anti - VCA IgM / IgG :- Anti viral capsid

IgM :- Acute infection then disappears
IgG ; may be Occurs in Acute infection, remains in convalescent


anti-EBNA IgG ( EB nuclear antigen)
Only occur in convalescent and indicates previous infection

#ููŠุฑูˆุณุงุช
#ู…ุงูŠูƒุฑูˆ
๐Ÿ›‘ Lymphocytosis is suspected lymphoma utill proven otherwise ..

๐Ÿ›‘ Lymphocytosis with Atypical T lymphocytes ..." feel safe "
It is infectioue Mononucleosis

๐Ÿ›‘ to Differentiate between infectioue Mononucleosis, and Infectious mononucleosis like syndrome

Infectious mononucleosis, With heterophills Antibodys in EBV

Infectious mononucleosis like, without Hetrophills antibodies in CMV

Both shows symptoms of:
Sore throat, fever , fatigue, lymphadenopathy , enlarged spleen , Hepatitis

#ููŠุฑูˆุณุงุช
#ู…ุงูŠูƒุฑูˆ
๐ŸƒWhy small pox is eridicated:-

1- it has only one stable stereotype.
2- The man is the only host
3- no reservoir host
4- no carrier
5- was the first to be controlled by vaccine
6- produce long lasting memory

#ููŠุฑูˆุณุงุช
#ู…ุงูŠูƒุฑูˆ
๐Ÿค”๐Ÿค” Small pox and Chickenpox:

Both are transmitted by droplets and contact ..

Small pox
โ—๏ธCaused by small pox viruse
โ—๏ธRash :- centrifugal
โ—๏ธStarts : macule , papule , vesicle , pustules, ends forming crust
โ—๏ธScar formation ..
And Fetal


Chicken pox :
โ• caused by VZV
โ• rash : Centripetal
โ• polymorphic ( all in same time )
Characterized by Umblicated lesion
โ• healed without scar
Not fetal

#ููŠุฑูˆุณุงุช
#ู…ุงูŠูƒุฑูˆ
๐Ÿค” Molliscum contagiosm and Human Papilloma warts

Molliscum contagiosm:-
โ—๏ธ Caused by MCV , Poxviruse
โ—๏ธ one genotype
โ—๏ธ Umblicated cheesy Papules
โ—๏ธ soft
โ—๏ธ called Human soft warts

Human Papilloma wart : -
โ—๏ธ Caused by HPV , Papovaviruses
โ—๏ธ>100 serotypes
โ—๏ธ cauliflower shaped ( Verruca Vuligaris)
โ—๏ธ rough
โ—๏ธcalled warts ( Verruca)

#ู…ุงูŠูƒุฑูˆ
#ููŠุฑูˆุณุงุช
๐Ÿ›‘HPV cannot be caltivated in vitro

๐Ÿ›‘ virus that transmitted through birth canal :- HSV- 2

๐Ÿ›‘ Human Papilloma virus:
Causes cervical carcinoma with genotype 16 ,18 ?
Because the virus produce oncoproteins integrated on DNA
E6 binds to P53
E7 Binds to Rb
Inactivation of This Tumor suppressor genes , Increase mitosis, tumor

๐Ÿ›‘ there is some strains of small pox with America and Russia, they may use them in the Bio terrorism.

๐Ÿ›‘ Oncolytic viral therapy is a new strategy by which ... There are Viral strains that kill the malignant cells , And stimulate the Immune system ?
How ?
When this virus infect the Tumor , it replicates itself untill the cell burst , ( Lysis of Tumor ) then the product of Bursting tumor cell initiate the immune response !

๐Ÿ›‘ Hydrops fetalis may be
Because , infant infected by Parvovirus B19 , Or due to RH incompatibility

#ููŠุฑูˆุณุงุช
#ู…ุงูŠูƒุฑูˆ
Surgical notes
๐ŸŒผDiseases caused by DNA viruses :- ๐ŸŒผ Herpsviridae:- 1- HSV-1 :- ( OroFacial) ๐Ÿ’ฅ 1- Herps Labialis ๐Ÿ’ฅ 2- Keratoconjunctivitis >> dendritic ulcer >> Bindness ๐Ÿ’ฅ 3- Gingivostomatitis ๐Ÿ’ฅ4- Herpetic Whitlow on Finger ๐Ÿ’ฅ 5- complication : Ecephalitis , Asepticโ€ฆ
ู‡ู†ุง ู…ูƒุชูˆุจุงุช ู…ุซู„ ุงู„ู…ู„ุฒู…ุฉ..

ุจุณ ุงู„ุฏูƒุชูˆุฑ ุนูƒุณ ุจูŠู†ู‡ู…

Jc : Progressive multifocal Luekoencephalopathy

Bk: Heamorrhagic Cystitis, Nephropathy

#ููŠุฑูˆุณุงุช
Forwarded from SHADDAD'S Summaries
Diseases and drug of choice .pdf
2 MB
ุฌุฏูˆู„ ู…ู„ุฎุต ุงู„ู…ู„ุฎุต ุชุฑู… ุงูˆู„ ูˆุซุงู†ูŠ ูุงุฑู…ุง ู…ุญุงุถุฑุงุช ุงู„ุฏูƒุชูˆุฑ ุนุฏู†ุงู†.
Disease + Drug of choice
ู…ุฎุทุทุงุช ูุงุฑู…ุง .pdf
815.1 KB
Brain-mab
ู„ุงุบู„ุจ ุงู„ุงู‚ุณุงู…
Schillerโ€“Duval body is a cellular structure seen by microscope in endodermal sinus tumors (yolk sac tumors) characterized by the presence of a central vessel, surrounded by epithelial tumor cells and fibrous tissue
#ุจุงุซูˆ
#ุงู„ุฏูƒุชูˆุฑุฉ_ู…ู†ูŠุฉ
Forwarded from Surgical notes
๐Ÿฅ›Milk-alkali syndrome ๐Ÿฅ›

is caused by the ingestion of large amounts of calcium and absorbable alkali, with resulting hypercalcemia. ... This syndrome was originally recognized in the 1920s during administration of the Sippy regimen, consisting of milk and bicarbonate, for treatment of peptic ulcer disease.( CaCo3)


Burnett's syndrome is far-advanced milk-alkalisyndrome and due to long-standing calcium and alkali ingestion. It is characterised by severe hypercalcaemia, irreversible renal failure, and phosphate retention. ... The patient is treated by withdrawal of excessive calcium and alkali intake.


#ูุงุฑู…ุง
ุฃุณู…ุงุก
New Doc 2019-11-21(1).pdf
ู…ูˆุงุถูŠุน :-

anticancer , anticoagulant , antiplatelet & hyperlipidemia
D.M

ุญุงู„ูŠ ุนู„ุดุงู† ุงุฎุชุจุงุฑ ุงู„ุดููˆูŠ ุจุณ ูŠู„ู… ุงู„ู…ูˆุถูˆุน ูˆุงู„ู…ุฑุงุฌุนุฉ ุงู„ู„ูŠ ู‡ูŠ ุตุจุญ ุงู„ุฅุฎุชุจุงุฑ


#ูุงุฑู…ุง ๐Ÿ’›
Forwarded from Deleted Account
ุงู„ู…ูˆุงุถูŠุน ุงู„ู…ู‡ู…ุฉ ููŠ ุงู„ GIT :

Q)Differentiate between ulcer and erosion?

ุตูุญู‡ 9
Tumer of salivary gland

ุตูุญู‡ 23
Defense mechanism

ุตูุญู‡ 25
ุงู„ุงุซู†ูŠู† ุงู„ุฌุฏุงูˆู„ ู…ู‡ู…ู‡ ุฌุฏุง

ุตูุญู‡ 28
ุงู„ุฌุฏูˆู„ ู…ู‡ู… ุฌุฏุง ุฌุฏุง
Q)write short account on gastric carcinoma?

ุตูุญู‡ 30
Acute abdomen(Main causes)

ุตูุญู‡ 31
Acute appendicitis
(pathogenesis and morphology)


ุตูุญู‡ 32
Differential diagnosis of acute appendicitis

ุตูุญู‡ 47
IBD ู…ูˆุถูˆุน ู…ู‡ู…
Crohn's disease ู…ูˆุถูˆุน ู…ู‡ู…
Q) Extra Intestinal manifestation of Crohn's disease?


ุตูุญู‡ 51
ุงู„ุฌุฏูˆู„ ู…ู‡ู…ู‡ ุฌุฏุง ุฌุฏุง

ุตูุญู‡ 53
Q) Compare between the neoplastic polyps or write short account?

ุตูุญู‡ 55
Colorectal carcinoma ู…ู‡ู…

54
familial polyposis syndrome

56
adenoma carcinoma sequence ู…ู‡ู…

58
Staging system of cancer colon ู…ู‡ู…(Mcq)

#ุจุงุซูˆ
Forwarded from ุงู„ู…ุฌู…ูˆุนุฉ ุงู„ุฑุงุจุนุฉ โฆโœŒ๏ธโฉ (Abraham)
ุนู„ุดุงู† ู†ุญูุธ ู†ู‚ุงุท ุงู„ู…ู‚ุงุฑู†ู‡ ุจูŠู† Uc ูˆ CD ุจู†ุจุฏุง ู†ู† ุฎุงุฑุฌ ูˆู†ุฏุฎู„ ุญุจู‡ ุญุจู‡ ู„ุจุทู† ุงู„ู…ุฑูŠุถ.
ู…ุฑูŠุถ ุงู„ IBD ู„ู…ู† ูŠุฌูŠ ู„ุนู†ุฏูƒ ุจูŠูƒูˆู† ูŠุนุงู†ูŠ ู…ู† ุงู„ู… ููŠ ุงู„ุจุทู† ุงู…ุง ูŠู…ูŠู† ุงูˆ ูŠุณุงุฑ
1. abdominal pain.
ุทูŠุจ ู‡ุฐุง ุงูˆู„ ู†ู‚ุทู‡ ู†ู‚ุงุฑู† ุจู‡ุง ุทูŠุจ ู„ูˆ ูุชุญู†ุง ุงู„ุจุทู† ูˆุดูู†ุง ุงู„ุงู…ุนุงุก ู…ุนุฑูˆู ุงู†ู‡ ูˆุงุญุฏ ุจูŠูƒูˆู† ููŠ ุงู„ rectum ูˆูˆุงุญุฏ ููŠ ileum
2 - rectal involvement.
3 - ileum involvement.

ู…ู† ู†ู‚ุทุฉ ุงู„ rectum ุจู†ุทู„ุน ู†ู‚ุทุชูŠู†
4. Rectal bleeding
5. Sparing of rectum

ูˆู‡ูˆู„ุง ุงู„ู†ู‚ุทุชูŠู† ุจูŠูƒูˆู†ูˆุง ู…ูˆุฌูˆุฏุงุช ุงูƒูŠุฏ ููŠ ุงู„ูŠ ูŠูƒูˆู† ุนู†ุฏู‡ ุงู„ู†ู‚ุทู‡ ุฑู‚ู… 2.
ุทูŠุจ ู„ูˆ ุนู…ู„ู†ุง section ุนุฑุถูŠ ูˆุทูˆู„ูŠ
ููŠ ุงู„ุณูƒุดู† ุงู„ุทูˆู„ูŠ ู…ุงุจุดูˆู ุทุจู‚ุงุช ุงู„ุงู…ุนุงุก ุจุณ ุจูŠููŠุฏู†ูŠ ู‡ุฐุง ุจู†ู‚ุทุชูŠู†
6. Distribution(
ู‡ุฐู‡ ุงุดูˆู ู‡ู„ ู‡ูˆ ู…ู†ุชุดุฑ ุน ุฌุฒุก ูƒุจูŠุฑ ุฏููŠูˆุฒ ูŠุนู†ูŠ ุงูˆ ุน ู…ูƒุงู† ูˆุงุญุฏ )
7. Skip areas
ูˆู‡ุฐู‡ ูƒู…ุงู† ู†ูุณ ุงู„ููƒุฑู‡
ุทูŠุจ ููŠ ุงู„ุณูƒุดู† ุงู„ุนุฑุถูŠ๐Ÿ”ต ุงูŠุด ุจุดูˆู... ุงูƒูŠุฏ lumen & layers
ุทูŠุจ ููŠ ุงู„ุงู„ูŠูˆู…ู† ุจุณุชููŠุฏ ู†ู‚ุทุฉ ุงู„ุชุถูŠู‚
8. stricture
ูˆููŠ layers ุจุณุชููŠุฏ ู†ู‚ุงุท ูƒุซูŠุฑ
9. Mucosal atrophy & regeneration
10. Fistula
11. Fissuring
12 .involvement ( transmural , transdermal)
13. Crypt abcess


ุทูŠุจ ุจู‚ูŠุฉ ุงู„ู†ู‚ุงุท ุจู†ู„ู…ู‡ู† ุจุญุงุฌุชูŠู† ู…ูŠูƒุฑูˆุณูƒูˆุจูŠ ูˆุชูŠูˆู…ุฑ
- microscopy
14. Cytoplasmic mucin
15. Edema
16. Granulation
17. Lymphoid aggregate
18. Hyperemia
19. L.N


- Tumor
20. Colon carcinoma

#ุจุงุซูˆ_ ุนุจุฏุงู„ู„ู‡ ุงู„ุฐุจุญุงู†ูŠ
Drugs that cause hypothyroidism:
1_antithyroid drugs.
2_lithium(used for mania , bipolar disorder and recurrent depression)
3_beta interferon(used for hepatitis and multiple sclerosis)
4_amiodarone (antiarrythemic drugs)
5_resorcinol(used for treatment of leg ulcer)
6_ fluoride ion

#pharma
Forwarded from Deleted Account
RivaroXaban = direct on Xa

Argatroban = direct on thrombin
Forwarded from Deleted Account
ูƒู„ ุงู„ู†ูŠู…ุงุชูˆุฏุง ุชุชุนุงู„ุฌ ( ุจุงุณุชุซู†ุงุก ุงู„ุง
Strongeloid stercoralis )
ุจุนู„ุงุฌูŠู†
1. Albendazol
ุฌุฑุนุชู‡ ุง ุง ุง ุฑุจุนู…ูŠู‡ 400
2. Mebendazol
ูˆุฌุฑุนุชู‡ ู… ู… ู… ู…ูŠู‡ 100
ูˆู…ุนู‡ ุชุณู„ุณู„
1,2,3
1 = 100
2= twice
3 = 3 days