❗️Diagnosis ...Massive pulmonary embolism

❗️Feature. ..Massive emboli inside pulmonary trunk in right and left branches leading to sudden death
#معمل_باثو
#سلايدات

❗️Diagnosis :-
Sarcoidosis
❗️❗️ Ft :-
Asteroid cells + Non caseating granuloma with many gainy cells
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#معمل_باثو

❗️ Diagnosis :-
Gastric Adenocarcinoma..

❗️ ft:-
Local invasion of Gland to the smooth muscle layer

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#معمل_باثو

❗️ Diagnosis :
Peptic Ulcer

❗️❗️ ft:-
1- Area of Necrosis
2- Acute inflammation
3- Granulation tissue ( with Blood vessels )
3- Area of chronic inflammation with Fibrosis

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#معمل_باثو

❗️Diagnosis:-
Chronic gastritis by h.pylori

❗️❗️ ft :-

نميزها بثلاث حاجات :'-
1- Lymphocytes infiltrate in form of Secondary Lymphoid Follicle
2- Intrs-epithilial Nuetrophils ( indicates Active infection )
3- H.pylori seen on 3 forms :
(Bacilli - Comma shape or spiral)

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#معمل_باثو

هذي ال Form of Secondary lymphoid follicle

طبعا أهم ميزتين للتفريق بينهم :- الثننين بنلاحظ فيهم Area of Necrosis
1- Benign :- يسار
Inverted Edges with normal thikness , regular necrosis

2- malignant:- يمين
Everted Edges , Thickned
Irregular

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#معمل_باثو

طبعا الثنتين يحصلوا في ال Gastric Gland
الفرق ان :-

Fundic polyp :- it is a hyperplasia of the gland without the Dysplastic Change

Adenoma :-
Dysplastic changes of the glands > pre- cancerous

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#معمل_باثو

طبعا من هنا وبعد
شرائح من موضوع اليوم GIT ركز عليهم الدكتور أكثر شي ..
و يمكن يجوا بالامتحان

#سلايدات
#معمل_الباثو

🔖Pyelonephritis :
- It is the inflammation of renal parenchyma and calyx.
- It is of 2 types : acute and chronic
- The most common causes are :
1- Ascending UTI and pelvic inflammatory disease.
2- Caused by hematogenous spread of severe infection
🔖Risk factors :
1- Urinary tract obstruction with stasis of urine secondary infection.
2- In females (due to the short urethra).
3- Pregnancy (compression on urethra).
4- Benign prostatic hyperplasia( BPH)
5- Vesico-ureteral reflex
6- Calculi. For more detalis about it is type look to picture👇🏻 #Renal_pathology #H_S

#Renal_pathology #H_S

Pathology Lab :-
⭐️ Vascular Pathology 🌟

#معمل_باثو
#مجموعة_الباثو

مساااكم الله بالخير 🌸
موضوع اليوم بنتحدث فيه عن ال vascular system
وعن الامراض المتعلقة فيه 😊

طبعاً ال vascular system
📌هو الأهم وذلك لأنه يرتبط بجميع ال systems of the body
So: اي خلل فيه سيؤثر على الأجهزة الأخرى في الجسم

📌50% من الوفيات بسبب مضاعفات لأمراض ال vascular system
مثل ال atherosclorosis and hypertention
●Start with Basics:-
🔹Anatomy:-
*Arterial part:- Aorta > large artery > medium a. > small a. >arterioles
*Capillaries
*Venous part:- Vanules > small veins > medium v. > large v. > sup. &inf. Vena cava

🔹Histology:-
3 layers ••
Intima - media - advintitia

1] intima composed of :-
a) endothelial cells (single layer of flat squemous cells).
It's function:- promote permability of B.V. , promote disturbance of clotting factors )
b) Subendothelial C.T.

2] media :- multiple layers of smooth muscle.

3] Adventatia :- C.T. contains (Arterial supply , veinus draining , nerve supply ).

🤔 كيف نقدر نفرق بين
different size of Arteries ؟؟
By it's thickening of media (it disappear at capillaries)

🔹physiology:-
Transmission the blood whole over the body

🔹phathology:-
كالعاده نبدأ بال:-
A]Congenital Anomalies:-
1)Arterio-venous malformation:
Formed mass ▶️ يعني شبكة من الأوعية الدموية متشابكة مع بعض ويحصل
(Blood stasis)

2]Arterio venous shunt (Fastula):
-It's abnormal connection between artery and vein
-it's common
-it's may be acquired by trauma
or by theraputic:-
علاجية مثل :- Urine dialysis غسيل الكلية

🤓the normal connection between artery and vein is Capillary

3]Berry aneurysm:-
🔴Aneurysm:- is abnormal permanent segmental dilatation of the arterial wall.
-Berry aneurysm: is Congenital dilatation of one of the branshes of circle of willis at the brain.

-it is Asymptomatic.
-but if it rupture by any cause (trauma) ▶️ it will lead to fatal intracerebral heamorrhage ▶️ Sudden death.

B] inflammation disease:- (vasculitis)
نقدر نقسمها الى قسمين بحسب السبب infectious &Non infectious

🔹infectious:-
- it caused more by syphilis
-it is rare,
because all immune cells are at the blood
يعني انتحار بالنسبه للميكروب ولكن قد يحصل vasculitis بسبب ميكروب في حالة انه المناعة صارت ضعيفه
😐 بنفس الوقت هذا سلاح ذو حدين صحيح انه صار محمي من ال infection ولكن صار اكثر عرضة لل Auto immune

🔹 Non infectious :- (Autoimmune)
-Common
-Classification according to the size of the effective blood veesels:-
نبدأ بالتقسيمه وبعدين بنشرح كل واحد ع حده 😊✌🏻

1) large size vasculitis:-
1- Takayaso.
2- Temporal Giant cells arteritis.
😌 الاثنين يبدأوا بحرف ال T

2)Medium size vasculitis:-
1- polyarteritis nodosa
2-Kauasaki

3)small size vasculitis:-
1-Microscobic polyangitis.
2- Wegener granulomatosis.
3- Churg-strauss syndrome.

🔹نتحدث اولاً عن ال
Buerger disease:-
-هذا المرض مرتبط بال Smokers
-ويصيب ال artery &vein and nerve ككل
-المريض يجي وفيه edema at the upper limb
And may loss of sensation because obstruction by the inflammed artery and vein.

قبل ما نبدأ بشرح كل نوع لازم نعرف
🔴The general features of Vasculitis:-
1]Thickening of the wall.
2]Narrowing of the lumen.
3] leukocyte infeltration
هذي العلامات بنشوفها بكل نوع

😊 نبدأ الان بشرح كل نوع وايش المميز فيه وكيف نعرف نفرق بينهن بالشرائح

1] large size vasculitis:-
-microcobic features both are the same :-
الاثنين متشابهين تحت المجهر طيب ايش نشوف ؟!
It characterized by Giant cell infltrate the wall ▶️ Granulomatus inflammation هذي علامة مميزه لهذا النوع
( specific histologic feature)

طيب كيف بقدر افرق بين النوعين🧐 ؟!
-They are different clinically
1]Temporal Giant cell arteritis:-
-affect temporal artery and it's branshes. So:-
المريض يعاني من : chronic headache -tenderness - blindness
-affect old patients.

2]Takayasu:-
-affect arch of aorta and it's branches.
-so the problem at vessels which supply upper limb (pulsless) علامة مميزة

🔹Disease:- Temporal Giant cell arteritis or Takayasu vasculitis
هنا نذكر المرضين لانه زي ما قلنا مانقدر نفرق بينهم الا clinically
🔹Features :-
The general features of vasculitis واضحه :-
1)thickening of the wall
2)narrowing of the lumen
3)leukocyte infeltrate
specific feature:- granulomatus inflammation with giant cells