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๐Ÿงฌ๐ŸงฌSegmented viruses:
๐Ÿฆ Arenaviridae>>>>2
๐Ÿฆ Bunyaviridae>>>>3
๐Ÿฆ Orthomyxoviridae>>8
๐Ÿฆ Reoviridae>>>>>10_12


๐Ÿ‘ถChildhood viral infections:
_This viruses affect unvaccinated children.
๐Ÿฆ Mumps
๐Ÿฆ Measles
๐Ÿฆ Rubella
๐Ÿฆ VZV
๐Ÿฆ Parvovirus B19
๐Ÿฆ HHV_6,7

๐ŸšบCongenital transmitted viruses:
๐Ÿฆ CMV
๐Ÿฆ Rubella
๐Ÿฆ Parvovirus B19
๐Ÿฆ VZV
๐Ÿฆ HIV
๐Ÿฆ HSV

๐Ÿ“”Sexually transmitted viruses:
๐Ÿ‘‰With genital signs_
๐Ÿฆ HPV
๐Ÿฆ HSV_1,2
๐Ÿ‘‰Without genital signs
๐Ÿฆ HIV
๐Ÿฆ HBV
๐Ÿฆ CMV

#virology
โšก๏ธSummary of viruses

โœViruses affect eye?
๐Ÿ‘‰Adenovirus>>conjunctivitis,keratoconjunctivitis.
๐Ÿ‘‰HSV>>conjunctivitis,keratitis(dendritic ulcer.
๐Ÿ‘‰Enterovirus type 70>>hemorrhagic conjunctivitis.
๐Ÿ‘‰VZV>>herpes zoster ophthalmics.


โœViruses affect ear?
All>>(otitis media,sinusitis)

๐Ÿ‘‰Adenovirus
๐Ÿ‘‰Respiratory syncytial_ virus(RSV)
๐Ÿ‘‰Rhinovirus


โœViruses affect Upper RT?
๐Ÿ’ฅDNA viruses.
๐Ÿ‘‰HSV_1,2(gingivostomatitis,cold sores)
๐Ÿ‘‰EBV(kissing disease,Nasopharyngeal carcinoma)
๐Ÿ‘‰HPV(laryngeal papillomas)
๐Ÿ‘‰CMV(infec. Monon. Like disease)
๐Ÿ‘‰Adenovirus(acute febrile pharyngitis,pharyngoconjunctival fever).

๐Ÿ’ฅRNA viruses.
๐Ÿ‘‰Coronaviruses(common cold)
๐Ÿ‘‰Rhinoviruses(common cold)
๐Ÿ‘‰Enteroviruses(pharyngitis
๐Ÿ‘‰Parainfluenza ,(RSV) rare
๐Ÿ‘‰Coxsackie A virus(herpangina,hand foot mouth disease)


โœViruses affect lower RT?
๐Ÿ’ฅDNA viruses.
๐Ÿ‘‰Adenovirus(acute respiratory disease).

๐Ÿ’ฅRNA viruses.
๐Ÿ‘‰Parainfluenza(croup,pneumonia)
๐Ÿ‘‰Influenza(mild Rhinotracheitis,fatal pneumonia)
๐Ÿ‘‰RSV(bronchiolitis,pneumonia)
๐Ÿ‘‰SARS Coronavirus(SARS)
๐Ÿ‘‰hMPV(bronchiolitis)
๐Ÿ‘‰Coxsackie B virus(pleurodynia or bornholm disease)
๐Ÿ‘‰Hantavirus(hantavirus Pulmonary syndrome)

โœviruses cause gastroenteritis?

๐Ÿ‘‰Rotaviruses. | Mainly in
๐Ÿ‘‰Adenovirus. | =neonate,
๐Ÿ‘‰Astroviruses | infant.
๐Ÿ‘‰Noroviruses(Norwalk virus)mainly in adult , school age children.


โœviruses cause hepatitis:
๐Ÿ’ฅDNA viruses.
๐Ÿ‘‰HSV
๐Ÿ‘‰CMV
๐Ÿ‘‰EBV
๐Ÿ‘‰HBV
๐Ÿ’ฅRNA viruses.
๐Ÿ‘‰HCV
๐Ÿ‘‰HAV
๐Ÿ‘‰HDV
๐Ÿ‘‰Rubella
๐Ÿ‘‰Yellow fever virus


โœviruses affect UT?
๐Ÿ‘‰Adenovirus(hemorrhagic cystitis).
๐Ÿ‘‰BK virus(latent kidney infection)

โœviruses affect CVS?

๐Ÿ‘‰Coxsackie B virus(myocarditis,pericarditis)
๐Ÿ‘‰Coxsackie A virus """" """""
๐Ÿ‘‰Echovirus """" """""
๐Ÿ‘‰Dengue virus(hemorrhagic fever,shock syndrome)


โœViruses affect skin,mucous M?
๐Ÿ‘‰HPV
๐Ÿ‘‰Molluscum contagiosum
๐Ÿ‘‰Orf virus
๐Ÿ‘‰HSV "VZV "HHV_6,7
๐Ÿ‘‰Parvovirus B19
๐Ÿ‘‰Measles
๐Ÿ‘‰Rubella
๐Ÿ‘‰Coxsackie
๐Ÿ‘‰Echovirus
#virology
Forwarded from Hashem Alsewari
Herpes family ููŠุฑูˆุณุงุช#
Forwarded from Hashem Alsewari
classification of RNAvirus ููŠุฑูˆุณุงุช#
Forwarded from Hashem Alsewari
Divided the viruses according to way of transmission and the common disease for each virus ููŠุฑูˆุณุงุช#
Forwarded from Hashem Alsewari
Comparison of hepatitis A,B,C,D & E ููŠุฑูˆุณุงุช#
Forwarded from Hashem Alsewari
The antivirus and them effect in viral replication ููŠุฑูˆุณุงุช#
Forwarded from Hashem Alsewari
Clinical feature of dengue virus infection ููŠุฑูˆุณุงุช#
ู„ู†ูƒู† ูŠุฏุง ูˆุงุญุฏู‡
ุฌู…ูŠุนุง ุบุฏุง ู…ู† ุงุฌู„ ู…ุตู„ุญุชู†ุง
#ุงู„ู„ุฌู†ุฉ_ุงู„ุนู„ู…ูŠุฉ
ุจุนุฏ ู…ุง ุงู†ุชู‡ูŠู†ุง ู…ู† ุฏุฑุงุณุฉ ุงู„ุจุงุซูˆู„ูˆุฌูŠ ุน ู…ุณุชูˆู‰ ุงู„ุฎู„ูŠุฉุŒ
ุงู„ุขู† ูˆู‚ุช ู†ุดูˆู ุงู„ุจุงุซูˆู„ูˆุฌูŠ ุน ู†ุทุงู‚ ุฃูˆุณุน-ุน ู…ุณุชูˆู‰ ุงู„ู†ุณูŠุฌ.

ูˆุจุณู… ุงู„ู„ู‡ ู†ุจุฏุฃ ู…ูˆุถูˆุน ุงู„inflammation..
ูˆุนู†ุจุฏุฃ ุงู„ูŠูˆู… ุจุงู„ู†ูˆุน ุงู„acute ู…ู†ู‡..

ูƒุฐุง ู†ุณุชุฑุฌุน ู…ุน ุจุนุถ ุงู„ู…ู„ุงู…ุญ ุงู„ุนุงู…ุฉ ู…ู† ุงู„ุฌุงู†ุจ ุงู„ู†ุธุฑูŠ ู„ู…ูˆุถูˆุนู†ุงุŒ

ุนุดุงู† ู…ุง ูŠูƒูˆู†ุด ูู‡ู…ู†ุง ู„ู„ุนู…ู„ูŠ ููŠ ู…ุนุฒู„ ู…ู† ุฏุงุฑุณุชู†ุง ููŠ ุงู„ู†ุธุฑูŠุŒ

ุงู„ุงู„ุชู‡ุงุจ ุงู„ุฐูŠ ู‡ูˆ
local response of the living vascularized tissues to injury.
ูŠู‡ู…ู†ุง ููŠู‡ ุงู„ุขุชูŠ:
1- Causes. (Infection, necrosis, immune reactions...).

2- Mechanism:
Has Two major compnents..
i- Reaction of blood vessels.
ii- Leukocytes and cellular events.

ุฃูˆ ู…ุน ุดูŠุก ู…ู† ุงู„ุชูุตูŠู„ ู†ุณู…ูŠู‡ุงุŒ
ุงู„sex Rs of acute inflammatory response:

ูˆุงู„ุฐูŠ ู‡ูŠ ูƒุงู„ุชุงู„ูŠ:
a- Recognition of causative agent.
b -Reaction of B.Vs.
c - Recruitment of leukocytes to the site of injury..
d - Removal of the caustive agent.
e - Regulation of inflimmatory response.
f- Resolution and Repair.

3- local signs of inflammation ููŠ ุฒูˆุงูŠุง ุงู„ู†ุฌู…ุฉ ุงู„ุฎู…ุณ
( Rubor, tumor, dolor, calor, and functio laesa).


4- Systemic Effects.. ( Fever, increase of acute phase ptns, changes in count of leukocytes, increase pulse pressure, anorexia, malaise, DIC in severe cases, shock..)

5-Outcomes of Acute Inflammation..
ูˆู‡ุฐุง ุนุชุฌุณุฑ ู„ู†ุง ุงู„ุฅู†ุชู‚ุงู„ ู„ู‚ุงุฏู… ุงู„ุฏุฑูˆุณ..
Chronic inflammation..
healing..
ุฃูˆ ููŠ ูƒุซูŠุฑ ุฃุญูŠุงู† ูŠุญุตู„ resolutionุŒ

6-ูˆุฃุฎูŠุฑุง ู…ุนุงู†ุง ู…ูˆุถูˆุน:
"morphologic types of acute inflammation".
ูˆูƒู…ุง ูŠูˆุญูŠ ู„ู†ุง ุงู„ุนู†ูˆุงู† ุฅู† ุงู„ู…ูˆุถูˆุน ููŠ ู…ุนุธู…ู‡ ุนู…ู„ูŠ ูˆูŠู„ุงู‡ ุจูŠู†ุง ู†ุจุฏุฃ ู…ูˆุถูˆุนู†ุง ููŠ ุงู„ุนู…ู„ูŠ ๐Ÿ‡..
#ู…ุนู…ู„_ุจุงุซูˆ
ูŠู‡ู…ู†ุง ููŠ ุงู„ู…ุนู…ู„ ุงู„ุชุงู„ูŠ:

1-Signs of acute infalmmation:

Grossly:
ุงู„ุฎู…ุณ ุงู„ู…ุฐูƒูˆุฑุฉ ููˆู‚..
"Slide 1"

and microscopically..HallMarks of acute inflammation( ๐Ÿ—ฃcommit them to ur gentle mind).

i -Acute inflimmatory infilterate.
ูŠุชูƒูˆู† ู…ู†:
A- neutrophils ุฃุณุงุณุงู‹.
ุฎุตูˆุตุง ููŠ ุงู„bactrrial..
B- esionphils.
ู†ุงุฏุฑุฉ ู…ุซู„ุง ููŠ ุญุงู„ุฉ ุงู„allergy and parasitic infection..
C-plasma cells.
D- lymphocytes.
ููŠ ุงู„viral ุชุญุฏูŠุฏุง..
E- Macrophages.

ii-congested Blood vessels.
iii- Edema..

" Slide 2 and 3"

3- Morphologic patterns:

a- Acute serious inflammation.
ู†ูุณ ุงู„ู‡ู„ู…ุงุฑูƒุณ ุญู‚ ุงู„ุฅู†ูู„ุงู…ุดู† ู„ูƒู† ุงู„edema ุชูƒูˆู† prominent ูˆุฃูƒูŠุฏ ู„ุฃู†ู‡ ุชูƒูˆู† ู…ู† transduate.
"Slide 5".

b. Acute fibrinous inflammation.
ู‡ุฐุง ูŠูƒูˆู† ููŠู‡ fibrin ุจูƒุซุงูุฉุŒ
ูˆุฃูƒูŠุฏ ุชูƒูˆู† ู…ู† exudate..
"Slide 8".
ูˆุฃูŠุถุง ู…ุนุงู†ุง ูƒุฃู…ุซู„ุฉ ู„ู‡ุง ุณู„ุงูŠุฏุงุช ุงู„
acute fibrinous pericarditis and pertonitis.

"Slide 13 a&b"
"Slide 14 a&b"


C. suppurative inflammation
ูˆุฃู‡ู… ุนู„ุงู…ุฉ ู„ู‡ ู‡ูŠ ุญุงุฌุฉ ูŠุณู…ูˆู‡ุง ุงู„pus..
ูƒูŠู ุฃุนุฑูู‡ุŸ!
ุฒุญู…ุฉ ุฎู„ุงูŠุง ู†ูŠุชุฑูˆููŠู„ุณ ู…ุนุธู…ู‡ุง ู…ุชุญู„ู„ ูˆู†ุณูŠุฌ ู…ุชุญู„ู„ ูˆุฎู„ุงูŠุง ุฏู… ุญู…ุฑุงุก ูŠุนู†ูŠ ุนูŠูƒูˆู† ู„ูˆ ุงู„ุณู„ุงูŠุฏ ุฅูŠุฒูŠู†ูˆููŠู„ูƒ..

ูˆู‡ุฐุง ุน ู†ูˆุนูŠู†:
localized: abscess..
"Slide 6& 7"
Diffuse:
ูˆู‡ุฐุง ุน ู†ูˆุนูŠู† ุฃูŠุถุง:
cellulitis
ู„ูƒู† ู…ุด ู…ู‚ุฑุฑ ุนู„ูŠู†ุง ุณู„ุงูŠุฏุงุช ู„ู‡ุฐู‡..
phlegmonous.
ูˆู‡ุฐู‡ ู…ุนุงู†ุง ูƒู…ุซุงู„ ุนู„ูŠู‡ุง ุณู„ุงูŠุฏ ููŠ ุงู„acute appendictis..
"Slide 10 a&b"

ูˆุนู†ุฃุญุฐู‡ุง ุจูƒุซูŠุฑ ุฅุณุชูุงุถุฉ ููŠ ุงู„GIT..


D.Ulcertive inflammation.
ูˆู‡ุฐุง ู…ู‡ู… ูˆู…ู† ุงู„ู…ุนู„ูˆู…ุงุช ุงู„ู„ูŠ ู„ุงุฒู… ุชูƒูˆู† ููŠ ุฑุคูˆุณ ุฃุตุงุจุนูƒ ู„ุฃู†ู‡ ู„ุงุฒู… ุชู…ูŠุฒู‡ุง ุนู† ุงู„malignant ulcer..

ูˆู‡ุฐุง ุงู„ู†ูˆุน ุงู„ุฐูŠ ูŠุญุฏุซ ุนู†ุฏ ุงู„surfaces ูˆู†ู‚ุณู…ู‡ุง ุจุญุณุจ ุงู„stage ู„ acute and chronic..
ูˆู…ุนุงู†ุง ูƒู…ุซุงู„ ู„ู‡ุง ุงู„Peptic ulcer..

"slide 15"
ูˆุนู†ุฃุฎุฐู‡ุง ุจุฅุณู‡ุงุจ ููŠ ุงู„GIT..

ูˆููŠ ุบูŠุฑ ู‡ุฐู‡ ุฃู†ูˆุงุน ูƒู…ุง ู‡ูˆ ู…ุนู„ูˆู… ู„ุฏูŠู†ุง ุฌู…ูŠุนุงุŒ
ู„ูƒู† ู…ุง ู„ู‡ุงุด ุณู„ุงูŠุฏุงุช..

ูˆุนู„ู‰ ุงู„ู„ู‡ ู‚ุตุฏ ุงู„ุณุจูŠู„

#ู…ุนู…ู„_ุจุงุซูˆ
Forwarded from Karim A. Al-Zazai
Slide 1
โ—๏ธDignosis:
Acute inflammation.
โ€ผ๏ธ Characteristic Features:
Redness and Swelling (Local signs of acute inflammation).

#ู…ุนู…ู„_ุจุงุซูˆ
#ุณู„ุงูŠุฏุงุช
Forwarded from Karim A. Al-Zazai
Slide 2
โ—D:Acute Inflammation.
โ€ผ๏ธC.Fs :(The two hallmarks of acute inflammation)
Congested BV.
Lecucyte infilterate of acute infammation (PMNCs, Plasma cells, few MCPs).
#ู…ุนู…ู„_ุจุงุซูˆ
#ุณู„ุงูŠุฏุงุช
Forwarded from Karim A. Al-Zazai
Slide 3:
โ—๏ธD: Acute Inflammation.
โ€ผ๏ธC.Fs:
BVs: Congested due to V.D.
Interstitial tissue: cellular exudate of acute infammation (Neutrophils mainly).
#ู…ุนู…ู„_ุจุงุซูˆ
#ุณู„ุงูŠุฏุงุช
Forwarded from Karim A. Al-Zazai
Slide 4:

โ—๏ธD: Acute Serious Inflammation.
โ€ผ๏ธC.Fs: Edema is prominent (Clear areas at upper corner).
Congested B.V.
Neutrophilic infilterate.
#ู…ุนู…ู„_ุจุงุซูˆ
#ุณู„ุงูŠุฏุงุช
Forwarded from Karim A. Al-Zazai
Slide 5:

โ—๏ธD: Acute Serious Inflammation.
โ€ผ๏ธ C.Fs:
neutrophilic infilterate.
Prominent edema.
B.V congestion.
#ู…ุนู…ู„_ุจุงุซูˆ
#ุณู„ุงูŠุฏุงุช
Forwarded from Karim A. Al-Zazai
Slide 6
โ—๏ธD: Acute suppurative inflammation (AKA Abscess or Pus).
โ€ผ๏ธ C.Fs:
1- Large No. of living and degenerated neutrophils.
2- RBCs.
3- Fibrin.
#ู…ุนู…ู„_ุจุงุซูˆ
#ุณู„ุงูŠุฏุงุช
Forwarded from Karim A. Al-Zazai
Slide 7

โ—๏ธD: Acute suppurative inflammation ( serious pericarditis).
โ€ผ๏ธC.Fs:
Thick layer of fibrin.
neutrophilic infilterate.
#ู…ุนู…ู„_ุจุงุซูˆ
#ุณู„ุงูŠุฏุงุช
Forwarded from Karim A. Al-Zazai
Slide 8
โ—๏ธD: Acute Fibrinoid Infammation.

โ€ผ๏ธC.F:
Fibrin deposition is prominent.
Congested B.V.
Neutrophilic infilterate.
#ู…ุนู…ู„_ุจุงุซูˆ
#ุณู„ุงูŠุฏุงุช
Forwarded from Karim A. Al-Zazai
Slide 9:

ุชุญูุฉ ู†ุงุฏุฑุฉ ู‡ุฐู‡ ุงู„ุตูˆุฑุฉ..โค๏ธ
โ—๏ธMargination.
โ€ผ๏ธNeutrophils are marginating at side of B.M.