15) When the MWt of protein is 50,000-200,000 the elimination site is/are:
Anonymous Quiz
6%
a) Blood.
25%
b) Kidney.
6%
c) Liver.
63%
d) Liver and kidney.
❤1
16) Proteolytic degradation of proteins can occur un specifically nearly everywhere in the body or can be limited to a specific organ or tissue.
Anonymous Quiz
93%
T
7%
F
17) ......... is a major site of protein metabolism with high proteolytic enzyme activity.
Anonymous Quiz
19%
a) Kidney
75%
b) GIT
0%
c) Blood
6%
d) Vascular endothelium
❤1
18) All the following is true about renal protein metabolism and excretion except:
Anonymous Quiz
19%
a) The kidneys are a major site of protein metabolism for smaller sized proteins.
38%
b) Tubular reabsorption is the rate limiting step.
19%
c) The size-selective cut-off for glomerular filtration is approximately 60 kD.
25%
d) Anionic macromolecules pass through the capillary wall less readily than neutral macromolecules.
19) If metabolic activity for the proteins is high in other body regions, there is only minor renal contribution to total clearance.
Anonymous Quiz
76%
T
24%
F
20) All the following is true about hepatic protein metabolism except:
Anonymous Quiz
19%
a) Exogenous proteins undergo proteolytic degradation to dipeptides and amino acids.
13%
b) The rate of hepatic metabolism largely dependent on specific amino acid sequence of the protein.
19%
c) Substances that enter the liver via carrier-mediated transport are excreted into the bile.
50%
d) Proteolysis usually starts with exopeptidases that give oligopeptides.
امتحن نفسك
1) The dose–exposure–response relationship and thus the dose of a drug required to achieve a certain effect are determined by the drug’s pharmacokinetic and pharmacodynamic.
#بايوتكنو_نظري لكجر 8 د.خالد
Pharmacokinetics and pharmacodynamics of protein drugs
Pharmacokinetics and pharmacodynamics of protein drugs