Calculated indices of volatile organic compounds (VOCs) in exhalation for #lung #cancer screening and early detection
https://2medical.news/2021/02/17/calculated-indices-of-volatile-organic-compounds-vocs-in-exhalation-for-lung-cancer-screening-and-early-detection/
Breath analysis is a promising noninvasive technique that offers a wide range of opportunities to facilitate early diagnosis of lung cancer (LC). Method Exhaled breath samples of 352 subjects including 160 with lung cancer (LC), 70 with benign pulmonary nodule (BPN) and 122 healthy controls (HC) were analyzed through thermal desorption coupled with gas chromatography-mass spectrometry (TD-GC–MS) to obtain the metabolic information from volatile organic …
https://2medical.news/2021/02/17/calculated-indices-of-volatile-organic-compounds-vocs-in-exhalation-for-lung-cancer-screening-and-early-detection/
Breath analysis is a promising noninvasive technique that offers a wide range of opportunities to facilitate early diagnosis of lung cancer (LC). Method Exhaled breath samples of 352 subjects including 160 with lung cancer (LC), 70 with benign pulmonary nodule (BPN) and 122 healthy controls (HC) were analyzed through thermal desorption coupled with gas chromatography-mass spectrometry (TD-GC–MS) to obtain the metabolic information from volatile organic …
American Society of Hematology 2021 guidelines for management of venous #thromboembolism: prevention and treatment in patients with #cancer
https://2medical.news/2021/03/05/american-society-of-hematology-2021-guidelines-for-management-of-venous-thromboembolism-prevention-and-treatment-in-patients-with-cancer/
Venous thromboembolism (VTE) is a common complication among patients with cancer. Patients with cancer and VTE are at a markedly increased risk for morbidity and mortality. Objective: These evidence-based guidelines of the American Society of Hematology (ASH) are intended to support patients, clinicians, and other health care professionals in their decisions about the prevention and treatment of VTE in patients with cancer. Methods: ASH formed …
https://2medical.news/2021/03/05/american-society-of-hematology-2021-guidelines-for-management-of-venous-thromboembolism-prevention-and-treatment-in-patients-with-cancer/
Venous thromboembolism (VTE) is a common complication among patients with cancer. Patients with cancer and VTE are at a markedly increased risk for morbidity and mortality. Objective: These evidence-based guidelines of the American Society of Hematology (ASH) are intended to support patients, clinicians, and other health care professionals in their decisions about the prevention and treatment of VTE in patients with cancer. Methods: ASH formed …
Broadened Eligibility for #Lung #Cancer Screening Challenges and Uncertainty for Implementation and Equity
https://2medical.news/2021/03/10/broadened-eligibility-for-lung-cancer-screening-challenges-and-uncertainty-for-implementation-and-equity/
In 2013, the US Preventive Services Task Force (USPSTF) recommended annual lung cancer screening with low-dose computed tomography (CT) in US adults aged 55 to 80 years who currently smoke or formerly smoked with a 30 pack-year history, and for those who formerly smoked, quitting within the past 15 years (grade “B” recommendation).1 In this issue of JAMA, the USPSTF updates this recommendation, proposing 2 …
https://2medical.news/2021/03/10/broadened-eligibility-for-lung-cancer-screening-challenges-and-uncertainty-for-implementation-and-equity/
In 2013, the US Preventive Services Task Force (USPSTF) recommended annual lung cancer screening with low-dose computed tomography (CT) in US adults aged 55 to 80 years who currently smoke or formerly smoked with a 30 pack-year history, and for those who formerly smoked, quitting within the past 15 years (grade “B” recommendation).1 In this issue of JAMA, the USPSTF updates this recommendation, proposing 2 …
ACG Clinical Guidelines: #Colorectal #Cancer Screening 2021
https://2medical.news/2021/03/12/acg-clinical-guidelines-colorectal-cancer-screening-2021/
1. We recommend CRC screening in average-risk individuals between ages 50 and 75 years to reduce incidence of advanced adenoma, CRC, and mortality from CRC. Strong recommendation; moderate-quality evidence 2. We suggest CRC screening in average-risk individuals between ages 45 and 49 years to reduce incidence of advanced adenoma, CRC, and mortality from CRC. Conditional recommendation; very low-quality evidence 3. We suggest that a decision …
https://2medical.news/2021/03/12/acg-clinical-guidelines-colorectal-cancer-screening-2021/
1. We recommend CRC screening in average-risk individuals between ages 50 and 75 years to reduce incidence of advanced adenoma, CRC, and mortality from CRC. Strong recommendation; moderate-quality evidence 2. We suggest CRC screening in average-risk individuals between ages 45 and 49 years to reduce incidence of advanced adenoma, CRC, and mortality from CRC. Conditional recommendation; very low-quality evidence 3. We suggest that a decision …
Effectiveness of Electroacupuncture or Auricular #Acupuncture vs Usual Care for Chronic Musculoskeletal Pain Among #Cancer Survivors The PEACE Randomized Clinical Trial
https://2medical.news/2021/03/20/effectiveness-of-electroacupuncture-or-auricular-acupuncture-vs-usual-care-for-chronic-musculoskeletal-pain-among-cancer-survivors-the-peace-randomized-clinical-trial/
The opioid crisis creates challenges for cancer pain management. Acupuncture confers clinical benefits for chronic nonmalignant pain, but its effectiveness in cancer survivors remains uncertain. Objective To determine the effectiveness of electroacupuncture or auricular acupuncture for chronic musculoskeletal pain in cancer survivors. Design, Setting, and Participants The Personalized Electroacupuncture vs Auricular Acupuncture Comparativeness Effectiveness (PEACE) trial is a randomized clinical trial that was conducted from …
https://2medical.news/2021/03/20/effectiveness-of-electroacupuncture-or-auricular-acupuncture-vs-usual-care-for-chronic-musculoskeletal-pain-among-cancer-survivors-the-peace-randomized-clinical-trial/
The opioid crisis creates challenges for cancer pain management. Acupuncture confers clinical benefits for chronic nonmalignant pain, but its effectiveness in cancer survivors remains uncertain. Objective To determine the effectiveness of electroacupuncture or auricular acupuncture for chronic musculoskeletal pain in cancer survivors. Design, Setting, and Participants The Personalized Electroacupuncture vs Auricular Acupuncture Comparativeness Effectiveness (PEACE) trial is a randomized clinical trial that was conducted from …
Therapeutic Repurposing of #Biguanides in #Cancer
https://2medical.news/2021/04/21/therapeutic-repurposing-of-biguanides-in-cancer/
Biguanides exert antitumor activities through various biochemical mechanisms involving mitochondrial complex I, AMP-activated protein kinase (AMPK), mammalian target of rapamycin (mTOR), and/or mitochondrial glycerophosphate dehydrogenase (mGPD). Biguanides selectively target subpopulations of cancer cells addicted to oxidative phosphorylation (OXPHOS). Metabolic adaptations triggered by biguanide exposure could be potential targets to improve the antitumor efficacy of biguanides. Biguanides modulate antitumor immunity by targeting immune cells in the …
https://2medical.news/2021/04/21/therapeutic-repurposing-of-biguanides-in-cancer/
Biguanides exert antitumor activities through various biochemical mechanisms involving mitochondrial complex I, AMP-activated protein kinase (AMPK), mammalian target of rapamycin (mTOR), and/or mitochondrial glycerophosphate dehydrogenase (mGPD). Biguanides selectively target subpopulations of cancer cells addicted to oxidative phosphorylation (OXPHOS). Metabolic adaptations triggered by biguanide exposure could be potential targets to improve the antitumor efficacy of biguanides. Biguanides modulate antitumor immunity by targeting immune cells in the …
NOX4 links metabolic regulation in #pancreatic #cancer to endoplasmic reticulum redox vulnerability and dependence on PRDX4
https://2medical.news/2021/05/08/nox4-links-metabolic-regulation-in-pancreatic-cancer-to-endoplasmic-reticulum-redox-vulnerability-and-dependence-on-prdx4/
https://2medical.news/2021/05/08/nox4-links-metabolic-regulation-in-pancreatic-cancer-to-endoplasmic-reticulum-redox-vulnerability-and-dependence-on-prdx4/
2Medical.News
NOX4 links metabolic regulation in #pancreatic #cancer to endoplasmic reticulum redox vulnerability and dependence on PRDX4
There is an urgent need to identify vulnerabilities in pancreatic ductal adenocarcinoma (PDAC). PDAC cells acquire metabolic changes that augment NADPH production and cytosolic redox homeostasis. H…
Indices of #Diet Quality and Risk of Lung #Cancer in the Women’s Health Initiative Observational Study
https://2medical.news/2021/05/23/indices-of-diet-quality-and-risk-of-lung-cancer-in-the-womens-health-initiative-observational-study/
https://2medical.news/2021/05/23/indices-of-diet-quality-and-risk-of-lung-cancer-in-the-womens-health-initiative-observational-study/
2Medical.News
Indices of #Diet Quality and Risk of Lung #Cancer in the Women’s Health Initiative Observational Study
Prospective evidence on associations between diet quality indices and lung cancer risk is limited, particularly among older women. ObjectivesWe investigated associations between 4 diet quality indi…
The association between occupational #asbestos exposure with the risk of incidence and mortality from #prostate #cancer: a systematic review and meta-analysis
https://2medical.news/2021/08/26/the-association-between-occupational-asbestos-exposure-with-the-risk-of-incidence-and-mortality-from-prostate-cancer-a-systematic-review-and-meta-analysis/
https://2medical.news/2021/08/26/the-association-between-occupational-asbestos-exposure-with-the-risk-of-incidence-and-mortality-from-prostate-cancer-a-systematic-review-and-meta-analysis/
2Medical.News
The association between occupational #asbestos exposure with the risk of incidence and mortality from #prostate #cancer: a systematic…
There is conflicting evidence on the association between asbestos exposure and prostate cancer (PCa). Two recent meta-analyses have claimed that exposure is associated with increased PCa incidence …
#Nut consumption in association with overall mortality and recurrence/disease-specific mortality among long-term breast #cancer survivors
https://2medical.news/2021/10/26/nut-consumption-in-association-with-overall-mortality-and-recurrence-disease-specific-mortality-among-long-term-breast-cancer-survivors/
https://2medical.news/2021/10/26/nut-consumption-in-association-with-overall-mortality-and-recurrence-disease-specific-mortality-among-long-term-breast-cancer-survivors/
2Medical.News
#Nut consumption in association with overall mortality and recurrence/disease-specific mortality among long-term breast #cancer…
High nut consumption is associated with reduced total and certain cause-specific mortality in general populations. However, its association with cancer outcomes among long-term breast cancer surviv…
#Depression, #anxiety, and the risk of #cancer: An individual participant data meta-analysis
https://2medical.news/2023/08/21/depression-anxiety-and-the-risk-of-cancer-an-individual-participant-data-meta-analysis/
https://2medical.news/2023/08/21/depression-anxiety-and-the-risk-of-cancer-an-individual-participant-data-meta-analysis/
2Medical.News
#Depression, #anxiety, and the risk of #cancer: An individual participant data meta-analysis
Depression and anxiety have long been hypothesized to be related to an increased cancer risk. Despite the great amount of research that has been conducted, findings are inconclusive. To provide a s…
Long-term #cancer outcomes after #bariatric surgery
https://2medical.news/2023/09/01/long-term-cancer-outcomes-after-bariatric-surgery/
https://2medical.news/2023/09/01/long-term-cancer-outcomes-after-bariatric-surgery/
2Medical.News
Long-term #cancer outcomes after #bariatric surgery
ObjectiveObesity is associated with increased cancer risk. Because of the substantial and sustained weight loss following bariatric surgery, postsurgical patients are ideal to study the association…
Detection of high-risk #polyps at screening colonoscopy indicates risk for #liver and #biliary #cancer death
https://2medical.news/2023/09/29/detection-of-high-risk-polyps-at-screening-colonoscopy-indicates-risk-for-liver-and-biliary-cancer-death/
https://2medical.news/2023/09/29/detection-of-high-risk-polyps-at-screening-colonoscopy-indicates-risk-for-liver-and-biliary-cancer-death/
2Medical.News
Detection of high-risk #polyps at screening colonoscopy indicates risk for #liver and #biliary #cancer death
Hepatobiliary cancers share risk factors with colorectal cancer (CRC), but there are no combined screening programs for these conditions.AimsThe aim of this study was to assess whether patients wit…
The #sex gap in #bladder cancer survival — a missing link in bladder #cancer care?
https://2medical.news/2023/10/28/the-sex-gap-in-bladder-cancer-survival-a-missing-link-in-bladder-cancer-care/
https://2medical.news/2023/10/28/the-sex-gap-in-bladder-cancer-survival-a-missing-link-in-bladder-cancer-care/
2Medical.News
The #sex gap in #bladder cancer survival — a missing link in bladder #cancer care?
The differences in bladder cancer outcomes between the sexes has again been highlighted. Uncommon among cancers, bladder cancer outcomes are notably worse for women than for men. Furthermore, bladd…
Consumption of ultra-processed #foods and risk of multimorbidity of #cancer and #cardiometabolic diseases: a multinational cohort study
https://2medical.news/2023/11/22/consumption-of-ultra-processed-foods-and-risk-of-multimorbidity-of-cancer-and-cardiometabolic-diseases-a-multinational-cohort-study/
https://2medical.news/2023/11/22/consumption-of-ultra-processed-foods-and-risk-of-multimorbidity-of-cancer-and-cardiometabolic-diseases-a-multinational-cohort-study/
2Medical.News
Consumption of ultra-processed #foods and risk of multimorbidity of #cancer and #cardiometabolic diseases: a multinational cohort…
It is currently unknown whether ultra-processed foods (UPFs) consumption is associated with a higher incidence of multimorbidity. We examined the relationship of total and subgroup consumption of U…
Association of #glycaemic index and glycaemic load with type 2 #diabetes, #cardiovascular disease, #cancer, and all-cause mortality: a meta-analysis of mega cohorts of more than 100 000 participants
https://2medical.news/2024/02/29/association-of-glycaemic-index-and-glycaemic-load-with-type-2-diabetes-cardiovascular-disease-cancer-and-all-cause-mortality-a-meta-analysis-of-mega-cohorts-of-more-than-100-000-partic/
https://2medical.news/2024/02/29/association-of-glycaemic-index-and-glycaemic-load-with-type-2-diabetes-cardiovascular-disease-cancer-and-all-cause-mortality-a-meta-analysis-of-mega-cohorts-of-more-than-100-000-partic/
2Medical.News
Association of #glycaemic index and glycaemic load with type 2 #diabetes, #cardiovascular disease, #cancer, and all-cause mortality:…
There is debate over whether the glycaemic index of foods relates to chronic disease. We aimed to assess the associations between glycaemic index (GI) and glycaemic load (GL) and type 2 diabetes, c…
Risk Factors and Incidence of #Gastric #Cancer After Detection of #Helicobacter pylori Infection: A Large Cohort Study
https://2medical.news/2024/04/05/risk-factors-and-incidence-of-gastric-cancer-after-detection-of-helicobacter-pylori-infection-a-large-cohort-study/
https://2medical.news/2024/04/05/risk-factors-and-incidence-of-gastric-cancer-after-detection-of-helicobacter-pylori-infection-a-large-cohort-study/
2Medical.News
Risk Factors and Incidence of #Gastric #Cancer After Detection of #Helicobacter pylori Infection: A Large Cohort Study
Risk Factors and Incidence of Gastric Cancer After Detection of Helicobacter pylori Infection: A Large Cohort StudyShria KumarDavid C. MetzSusan EllenbergDavid E. KaplanDavid S. Goldberg Published:…
#Virtual reality for #pain management in hospitalized patients with #cancer: A randomized controlled trial
https://2medical.news/2024/04/10/virtual-reality-for-pain-management-in-hospitalized-patients-with-cancer-a-randomized-controlled-trial/
https://2medical.news/2024/04/10/virtual-reality-for-pain-management-in-hospitalized-patients-with-cancer-a-randomized-controlled-trial/
2Medical.News
#Virtual reality for #pain management in hospitalized patients with #cancer: A randomized controlled trial
Hospitalized patients with cancer often experience acute and/or chronic pain. Although virtual reality (VR) has been extensively studied across a wide range of clinical settings, no studies have ye…
#Urticaria and the risk of #cancer: a Danish population-based cohort study
https://2medical.news/2024/07/23/urticaria-and-the-risk-of-cancer-a-danish-population-based-cohort-study/
https://2medical.news/2024/07/23/urticaria-and-the-risk-of-cancer-a-danish-population-based-cohort-study/
2Medical.News
#Urticaria and the risk of #cancer: a Danish population-based cohort study
BackgroundUrticaria has been tentatively linked to cancer, but epidemiological evidence supporting this link is sparse and conflicting. We therefore conducted a population-based cohort study using …