Face #masks effectively limit the probability of #SARS-CoV-2 transmission
https://2medical.news/2021/05/22/face-masks-effectively-limit-the-probability-of-sars-cov-2-transmission/
https://2medical.news/2021/05/22/face-masks-effectively-limit-the-probability-of-sars-cov-2-transmission/
2Medical.News
Face #masks effectively limit the probability of #SARS-CoV-2 transmission
Airborne transmission by droplets and aerosols is important for the spread of viruses. Face masks are a well-established preventive measure, but their effectiveness for mitigating SARS-CoV-2 transm…
First case of postmortem study in a patient vaccinated against #SARS-CoV-2
https://2medical.news/2021/06/15/first-case-of-postmortem-study-in-a-patient-vaccinated-against-sars-cov-2/
https://2medical.news/2021/06/15/first-case-of-postmortem-study-in-a-patient-vaccinated-against-sars-cov-2/
2Medical.News
First case of postmortem study in a patient vaccinated against #SARS-CoV-2
Highlights•We report on a patient with a single dose of vaccine against SARS-CoV-2. •He developed relevant serum titer levels but died 4 weeks later. •By postmortem molecular mapping, we found vira…
Multiple #SARS-CoV-2 variants escape neutralization by #vaccine-induced humoral immunity
https://2medical.news/2021/06/21/multiple-sars-cov-2-variants-escape-neutralization-by-vaccine-induced-humoral-immunity/
https://2medical.news/2021/06/21/multiple-sars-cov-2-variants-escape-neutralization-by-vaccine-induced-humoral-immunity/
2Medical.News
Multiple #SARS-CoV-2 variants escape neutralization by #vaccine-induced humoral immunity
Vaccination elicits immune responses capable of potently neutralizing SARS-CoV-2. However, ongoing surveillance has revealed the emergence of variants harboring mutations in spike, the main target …
Dynamic innate immune response determines susceptibility to #SARS-CoV-2 infection and early replication kinetics
https://2medical.news/2021/06/23/dynamic-innate-immune-response-determines-susceptibility-to-sars-cov-2-infection-and-early-replication-kinetics/
https://2medical.news/2021/06/23/dynamic-innate-immune-response-determines-susceptibility-to-sars-cov-2-infection-and-early-replication-kinetics/
2Medical.News
Dynamic innate immune response determines susceptibility to #SARS-CoV-2 infection and early replication kinetics
Initial replication of SARS-CoV-2 in the upper respiratory tract is required to establish infection, and the replication levelcorrelates with the likelihood of viral transmission. Here, we examined…
Vaccine Breakthrough Infections with #SARS-CoV-2 Variants
https://2medical.news/2021/06/25/vaccine-breakthrough-infections-with-sars-cov-2-variants/
https://2medical.news/2021/06/25/vaccine-breakthrough-infections-with-sars-cov-2-variants/
2Medical.News
Vaccine Breakthrough Infections with #SARS-CoV-2 Variants
Emerging variants of severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2) are of clinical concern. In a cohort of 417 persons who had received the second dose of BNT162b2 (Pfizer–BioNTech) …
Acute and long-term disruption of #glycometabolic control after #SARS-CoV-2 infection
https://2medical.news/2021/06/29/acute-and-long-term-disruption-of-glycometabolic-control-after-sars-cov-2-infection/
https://2medical.news/2021/06/29/acute-and-long-term-disruption-of-glycometabolic-control-after-sars-cov-2-infection/
2Medical.News
Acute and long-term disruption of #glycometabolic control after #SARS-CoV-2 infection
Patients with coronavirus disease 2019 (COVID-19) are reported to have a greater prevalence of hyperglycaemia. Cytokine release as a consequence of severe acute respiratory syndrome coronavirus 2 i…
Common #dandelion (Taraxacum officinale) efficiently blocks the interaction between ACE2 cell surface receptor and #SARS-CoV-2 spike protein D614, mutants D614G, N501Y, K417N and E484K in vitro
https://2medical.news/2021/06/30/common-dandelion-taraxacum-officinale-efficiently-blocks-the-interaction-between-ace2-cell-surface-receptor-and-sars-cov-2-spike-protein-d614-mutants-d614g-n501y-k417n-and-e484k-in-vitro/
https://2medical.news/2021/06/30/common-dandelion-taraxacum-officinale-efficiently-blocks-the-interaction-between-ace2-cell-surface-receptor-and-sars-cov-2-spike-protein-d614-mutants-d614g-n501y-k417n-and-e484k-in-vitro/
2Medical.News
Common #dandelion (Taraxacum officinale) efficiently blocks the interaction between ACE2 cell surface receptor and #SARS-CoV-2…
bioRxiv posts many COVID19-related papers. A reminder: they have not been formally peer-reviewed and should not guide health-related behavior or be reported in the press as conclusive. On 11th Marc…
Deaths in Children and #Young People in England following #SARS-CoV-2 infection during the first pandemic year: a national study using linked mandatory child death reporting data
https://2medical.news/2021/07/15/deaths-in-children-and-young-people-in-england-following-sars-cov-2-infection-during-the-first-pandemic-year-a-national-study-using-linked-mandatory-child-death-reporting-data/
https://2medical.news/2021/07/15/deaths-in-children-and-young-people-in-england-following-sars-cov-2-infection-during-the-first-pandemic-year-a-national-study-using-linked-mandatory-child-death-reporting-data/
2Medical.News
Deaths in Children and #Young People in England following #SARS-CoV-2 infection during the first pandemic year: a national study…
This is a preprint. It has not completed peer review. Background Deaths in children and young people (CYP) following SARS-CoV-2 infection are rare. Quantifying the risk of mortality is challenging …
#Masitinib is a broad coronavirus 3CL inhibitor that blocks replication of #SARS-CoV-2
https://2medical.news/2021/07/28/masitinib-is-a-broad-coronavirus-3cl-inhibitor-that-blocks-replication-of-sars-cov-2/
https://2medical.news/2021/07/28/masitinib-is-a-broad-coronavirus-3cl-inhibitor-that-blocks-replication-of-sars-cov-2/
2Medical.News
#Masitinib is a broad coronavirus 3CL inhibitor that blocks replication of #SARS-CoV-2
There is an urgent need for antiviral agents that treat SARS-CoV-2 infection. We screened a library of 1,900 clinically safe drugs against OC43, a human beta-coronavirus that causes the common cold…
Limited protection against #SARS-CoV-2 infection and virus transmission after mRNA #vaccination
https://2medical.news/2021/08/01/limited-protection-against-sars-cov-2-infection-and-virus-transmission-after-mrna-vaccination/
https://2medical.news/2021/08/01/limited-protection-against-sars-cov-2-infection-and-virus-transmission-after-mrna-vaccination/
2Medical.News
Limited protection against #SARS-CoV-2 infection and virus transmission after mRNA #vaccination
Stang and coworkers have recently reported in the Journal that “RT-PCR test results as gold standard for assessing and controlling infectiousness fail” (1). The authors analyzed two scenarios and u…
Vaccinated and unvaccinated individuals have similar viral #loads in communities with a high prevalence of the #SARS-CoV-2 delta variant
https://2medical.news/2021/08/02/vaccinated-and-unvaccinated-individuals-have-similar-viral-loads-in-communities-with-a-high-prevalence-of-the-sars-cov-2-delta-variant/
https://2medical.news/2021/08/02/vaccinated-and-unvaccinated-individuals-have-similar-viral-loads-in-communities-with-a-high-prevalence-of-the-sars-cov-2-delta-variant/
2Medical.News
Vaccinated and unvaccinated individuals have similar viral #loads in communities with a high prevalence of the #SARS-CoV-2 delta…
SARS-CoV-2 variant B.1.617.2 (delta) is associated with higher viral loads [1] and increased transmissibility relative to other variants, as well as partial escape from polyclonal and monoclonal an…
Infection-enhancing anti-#SARS-CoV-2 antibodies recognize both the original Wuhan/D614G strain and #Delta variants. A potential risk for mass vaccination ?
https://2medical.news/2021/08/19/infection-enhancing-anti-sars-cov-2-antibodies-recognize-both-the-original-wuhan-d614g-strain-and-delta-variants-a-potential-risk-for-mass-vaccination/
https://2medical.news/2021/08/19/infection-enhancing-anti-sars-cov-2-antibodies-recognize-both-the-original-wuhan-d614g-strain-and-delta-variants-a-potential-risk-for-mass-vaccination/
2Medical.News
Infection-enhancing anti-#SARS-CoV-2 antibodies recognize both the original Wuhan/D614G strain and #Delta variants. A potential…
Infection-enhancing antibodies have been detected in symptomatic Covid-19•Antibody dependent enhancement (ADE) is a potential concern for vaccines•Enhancing antibodies recognize both the Wuhan stra…
Limited protection against #SARS-CoV-2 infection and virus transmission after mRNA #vaccination
https://2medical.news/2021/09/03/limited-protection-against-sars-cov-2-infection-and-virus-transmission-after-mrna-vaccination-2/
https://2medical.news/2021/09/03/limited-protection-against-sars-cov-2-infection-and-virus-transmission-after-mrna-vaccination-2/
2Medical.News
Limited protection against #SARS-CoV-2 infection and virus transmission after mRNA #vaccination
Stang and coworkers have recently reported in the Journal that “RT-PCR test results as gold standard for assessing and controlling infectiousness fail”[1]. The authors analyzed two scenarios and us…
#Probenecid inhibits #SARS-CoV-2 replication in vivo and in vitro
https://2medical.news/2021/09/11/probenecid-inhibits-sars-cov-2-replication-in-vivo-and-in-vitro/
https://2medical.news/2021/09/11/probenecid-inhibits-sars-cov-2-replication-in-vivo-and-in-vitro/
2Medical.News
#Probenecid inhibits #SARS-CoV-2 replication in vivo and in vitro
Effective vaccines are slowing the COVID-19 pandemic, but SARS-CoV-2 will likely remain an issue in the future making it important to have therapeutics to treat patients. There are few options for …
Adenoviral Vector DNA- and #SARS-CoV-2 mRNA-Based Covid-19 Vaccines: Possible Integration into the Human #Genome – Are Adenoviral Genes Expressed in Vector-based Vaccines?
https://2medical.news/2021/09/26/adenoviral-vector-dna-and-sars-cov-2-mrna-based-covid-19-vaccines-possible-integration-into-the-human-genome-are-adenoviral-genes-expressed-in-vector-based-vaccines/
https://2medical.news/2021/09/26/adenoviral-vector-dna-and-sars-cov-2-mrna-based-covid-19-vaccines-possible-integration-into-the-human-genome-are-adenoviral-genes-expressed-in-vector-based-vaccines/
2Medical.News
Adenoviral Vector DNA- and #SARS-CoV-2 mRNA-Based Covid-19 Vaccines: Possible Integration into the Human #Genome – Are Adenoviral…
This brief review was presented here to facilitate an independent and more balanced discussion on the potential risks due to the presence of adenovirus vector DNA (AstraZeneca, Johnson & Johnso…
Transmission of community- and hospital-acquired #SARS-CoV-2 in hospital settings in the UK: A cohort study
https://2medical.news/2021/10/16/transmission-of-community-and-hospital-acquired-sars-cov-2-in-hospital-settings-in-the-uk-a-cohort-study/
https://2medical.news/2021/10/16/transmission-of-community-and-hospital-acquired-sars-cov-2-in-hospital-settings-in-the-uk-a-cohort-study/
2Medical.News
Transmission of community- and hospital-acquired #SARS-CoV-2 in hospital settings in the UK: A cohort study
Nosocomial spread of Severe Acute Respiratory Syndrome Coronavirus 2 (SARS-CoV-2) has been widely reported, but the transmission pathways among patients and healthcare workers (HCWs) are unclear. I…
Association of #Statins and 28-Day Mortality in Patients Hospitalized with #SARS CoV-2 Infection
https://2medical.news/2021/10/24/association-of-statins-and-28-day-mortality-in-patients-hospitalized-with-sars-cov-2-infection/
https://2medical.news/2021/10/24/association-of-statins-and-28-day-mortality-in-patients-hospitalized-with-sars-cov-2-infection/
2Medical.News
Association of #Statins and 28-Day Mortality in Patients Hospitalized with #SARS CoV-2 Infection
Statins may be protective in SARS-CoV-2 infection. The aim of this study was to evaluate the effect of in-hospital statin use on 28-day mortality and ICU admission among patients with SARS-CoV-2 st…
#Shedding of Infectious #SARS-CoV-2Despite Vaccination
https://2medical.news/2021/11/01/shedding-of-infectious-sars-cov-2despite-vaccination/
https://2medical.news/2021/11/01/shedding-of-infectious-sars-cov-2despite-vaccination/
2Medical.News
#Shedding of Infectious #SARS-CoV-2Despite Vaccination
The SARS-CoV-2 Delta variant might cause high viral loads, is highly transmissible, and containsmutations that confer partial immune escape 1,2. Outbreak investigations suggest that vaccinatedperso…
The spike protein of #SARS-CoV-2 variant A.30 is heavily #mutated and evades vaccine-induced antibodies with high efficiency
https://2medical.news/2021/11/06/the-spike-protein-of-sars-cov-2-variant-a-30-is-heavily-mutated-and-evades-vaccine-induced-antibodies-with-high-efficiency/
https://2medical.news/2021/11/06/the-spike-protein-of-sars-cov-2-variant-a-30-is-heavily-mutated-and-evades-vaccine-induced-antibodies-with-high-efficiency/
2Medical.News
The spike protein of #SARS-CoV-2 variant A.30 is heavily #mutated and evades vaccine-induced antibodies with high efficiency
The COVID-19 pandemic, caused by SARS-CoV-2, continues to rage in many countries, straining health systems and economies. Vaccines protect against severe disease and death and are considered centra…
A class II MHC-targeted vaccine elicits immunity against #SARS-CoV-2 and its variants
https://2medical.news/2021/11/08/a-class-ii-mhc-targeted-vaccine-elicits-immunity-against-sars-cov-2-and-its-variants/
https://2medical.news/2021/11/08/a-class-ii-mhc-targeted-vaccine-elicits-immunity-against-sars-cov-2-and-its-variants/
2Medical.News
A class II MHC-targeted vaccine elicits immunity against #SARS-CoV-2 and its variants
Vaccines remain the best hope of curtailing SARS-CoV-2 transmission, morbidity, and mortality. Currently available vaccines require cold storage and sophisticated manufacturing capacity, complicati…