#ABCA13 dysfunction associated with #psychiatric disorders causes impaired cholesterol trafficking
https://2medical.news/2020/12/31/abca13-dysfunction-associated-with-psychiatric-disorders-causes-impaired-cholesterol-trafficking/
ATP-binding cassette subfamily A member 13 (ABCA13) is predicted to be the largest ABC protein, consisting of 5,058 amino acids and a long N-terminal region. Mutations in the ABCA13 gene were reported to increase the susceptibility to schizophrenia, bipolar disorder and major depression. However, little is known about the molecular functions of ABCA13 or how they associate with psychiatric disorders. Here, we examined the biochemical …
https://2medical.news/2020/12/31/abca13-dysfunction-associated-with-psychiatric-disorders-causes-impaired-cholesterol-trafficking/
ATP-binding cassette subfamily A member 13 (ABCA13) is predicted to be the largest ABC protein, consisting of 5,058 amino acids and a long N-terminal region. Mutations in the ABCA13 gene were reported to increase the susceptibility to schizophrenia, bipolar disorder and major depression. However, little is known about the molecular functions of ABCA13 or how they associate with psychiatric disorders. Here, we examined the biochemical …