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Aldo Lorenzetti M.D, Internal Medicine & Hepatology, Milano - SIMEDET Delegate
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Associations of #sleep duration with patient-reported outcomes and healthcare use in U.S. adults with #asthma
https://2medical.news/2020/05/20/associations-of-sleep-duration-with-patient-reported-outcomes-and-healthcare-use-in-u-s-adults-with-asthma/

..Asthma was identified by self-report. Habitual hours of sleep duration were categorized as short (≤5), normal (6-8), and long (≥9). Multivariate regression analyses were used to examine the associations between sleep duration and patient-reported outcomes and healthcare use. Results Of the 1389 adults with asthma, 26% reported short sleep duration, 66% reported normal sleep duration, and 8% reported long sleep duration. Those with short sleep …
Multimorbidity in #asthma, association with allergy, inflammatory markers and symptom burden, results from the Swedish GA2LEN study
https://2medical.news/2020/10/19/multimorbidity-in-asthma-association-with-allergy-inflammatory-markers-and-symptom-burden-results-from-the-swedish-ga2len-study/

..Subjects with asthma, rhinitis and eczema were more likely to be sensitised to seasonal allergens (67 vs 32%, p<0.001), food allergens (54 vs. 18%, p<0.001) and to have a higher degree of sensitisation than subjects with only asthma (23 vs 10%, p<0.001). Subjects with allergic multimorbidity more often had allergic reactions to food (28 vs 10%, p=0.002), more respiratory symptoms and anxiety/depression (40% vs, 14%, …
Managing #Asthma in Adolescents and Adults 2020 Asthma Guideline Update From the National Asthma Education and Prevention Program
https://2medical.news/2020/12/07/managing-asthma-in-adolescents-and-adults-2020-asthma-guideline-update-from-the-national-asthma-education-and-prevention-program/

Asthma is a major public health problem worldwide and is associated with excess morbidity, mortality, and economic costs associated with lost productivity. The National Asthma Education and Prevention Program has released the 2020 Asthma Guideline Update with updated evidence-based recommendations for treatment of patients with asthma.. ..From 20 572 identified references, 475 were included in the 6 systematic reviews to form the evidence basis for these …
Poor outcome of #SARS-CoV-2 infection in patients with severe #asthma on biologic therapy
https://2medical.news/2020/12/26/poor-outcome-of-sars-cov-2-infection-in-patients-with-severe-asthma-on-biologic-therapy/

It is unclear whether asthma and asthma medications increase or decrease the risk of severe COVID-19, and this is particularly true for patients with severe asthma receiving biologics. Objectives The aim of this study was to assess incidence and disease course of COVID-19 in patients with severe asthma on biologic therapy (omalizumab, mepolizumab, reslizumab, benralizumab, dupilumab), as compared with COVID-19 data from the general Dutch …
#Antibiotic exposure during pregnancy and childhood #asthma: a national birth cohort study investigating timing of exposure and mode of delivery
https://2medical.news/2021/02/16/antibiotic-exposure-during-pregnancy-and-childhood-asthma-a-national-birth-cohort-study-investigating-timing-of-exposure-and-mode-of-delivery/

…A total of 5522 (17%) children were born to mothers exposed to antibiotics during pregnancy. In adjusted analyses, children born to exposed mothers had higher odds of asthma (OR 1.14, 95% CI 1.05 to 1.24). There was no association with antibiotic exposure in the first trimester (OR 1.02, 95% CI 0.83 to 1.26), but higher odds were observed for antibiotic exposure in the second to …