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#Mental Illness Among Youth With Chronic #Physical Conditions

https://pediatrics.aappublications.org/content/early/2019/06/13/peds.2018-1819

Youth with chronic physical conditions (CPCs) may be at greater risk for developing chronic mental health conditions (MHCs), and limitations in the ability to engage in developmentally appropriate activities may contribute to the risk of MHCs among youth with CPCs.

The 2-year cumulative incidence of MHCs was 7.8% overall, 11.5% in youth with CPCs (14.7% of sample), and 7.1% in those without. The adjusted risk of incident MHCs was 51% greater (adjusted hazard ratio 1.51; 95% confidence interval 1.30–1.74) in youth with CPCs compared with those without. Activity limitations mediated 13.5% of this relationship (P < .001).

CONCLUSIONS: This nationally representative cohort study supports the hypotheses that youth with CPCs have increased risk for MHCs and that activity limitations may play a role in MHC development. Youth with CPCs may benefit from services to bolster their ability to participate in developmentally important activities and to detect and treat new onset MHC

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The Predictive Performance of Objective Measures of #physical Activity Derived From Accelerometry Data for 5-Year All-Cause Mortality in #Older Adults: National Health and Nutritional Examination Survey 2003–2006

Declining physical activity (PA) is a hallmark of aging. Wearable technology provides reliable measures of the frequency, duration, intensity, and timing of PA..

In univariate logistic regression, the total activity count was the best predictor of 5-year mortality (Area under the Curve (AUC) = 0.771) followed by age (AUC = 0.758). Overall, 9 of the top 10 predictors were objective PA measures (AUC from 0.771 to 0.692). In multivariate regression, the 10-fold cross-validated AUC was 0.798 for the model without objective PA variables (9 predictors) and 0.838 for the forward selection model with objective PA variables (13 predictors). The Net Reclassification Index was substantially improved by adding objective PA variables (p < .001).

Conclusions
Objective accelerometry-derived PA measures outperform traditional predictors of 5-year mortality, including age. This highlights the importance of wearable technology for providing reproducible, unbiased, and prognostic biomarkers of health.

https://academic.oup.com/biomedgerontology/advance-article-abstract/doi/10.1093/gerona/glz193/5555985

Amount and Intensity of Leisure-Time #Physical Activity and Lower #Cancer Risk

To determine whether recommended amounts of leisure-time physical activity (ie, 7.5-15 metabolic equivalent task [MET] hours/week) are associated with lower cancer risk..

..Engagement in recommended amounts of activity (7.5-15 MET hours/week) was associated with a statistically significant lower risk of 7 of the 15 cancer types studied, including colon (8%-14% lower risk in men), breast (6%-10% lower risk), endometrial (10%-18% lower risk), kidney (11%-17% lower risk), myeloma (14%-19% lower risk), liver (18%-27% lower risk), and non-Hodgkin lymphoma (11%-18% lower risk in women). The dose response was linear in shape for half of the associations and nonlinear for the others. Results for moderate- and vigorous-intensity leisure-time physical activity were mixed. Adjustment for body mass index eliminated the association with endometrial cancer but had limited effect on other cancer types.

CONCLUSION

Health care providers, fitness professionals, and public health practitioners should encourage adults to adopt and maintain physical activity at recommended levels to lower risks of multiple cancers.

https://bit.ly/2F1Qfwj

Association Between #Weight Loss and Spontaneous Changes in #Physical Inactivity in Overweight/Obese Individuals With Knee Osteoarthritis: An Eight‐Week Prospective Cohort Study
https://2medical.news/2020/03/07/association-between-weight-loss-and-spontaneous-changes-in-physical-inactivity-in-overweight-obese-individuals-with-knee-osteoarthritis-an-eight%E2%80%90week-prospective-cohort-study/

To describe spontaneous changes in time spent being physically inactive that is measured continuously by accelerometry during an 8‐week weight‐loss intervention in overweight/obese individuals with knee osteoarthritis (OA).. A total of 124 participants completed the dietary intervention and had valid accelerometer recordings. The mean weight loss was 12.7 kg (95% confidence interval [95% CI] –13.2, –12.1; P < 0.0001) after 8 weeks, which corresponded to …

Effect of time of day of recreational and household #physical activity on prostate and breast #cancer risk (MCC‐Spain study)
https://2medical.news/2020/10/22/effect-of-time-of-day-of-recreational-and-household-physical-activity-on-prostate-and-breast-cancer-risk-mcc%E2%80%90spain-study/

Experimental evidence indicates that exercise performed at different times of the day may affect circadian rhythms and circadian disruption has been linked to breast and prostate cancer. We examined in a population‐based case‐control study (MCC‐Spain) if the time‐of‐day when physical activity is done affects prostate and breast cancer risk. Lifetime recreational and household physical activity was assessed by in‐person interviews. Information on time‐of‐day of activity …

Inadequate #Physical Activity and #Sedentary Behavior Are Independent Predictors of Nonalcoholic Fatty #Liver Disease
https://2medical.news/2020/10/30/inadequate-physical-activity-and-ssedentary-behavior-are-independent-predictors-of-nonalcoholic-fatty-liver-disease/

In general, physical activity (PA) and nonalcoholic fatty liver disease (NAFLD) have an inverse association. However, studies assessing the impact of the widely accepted Physical Activity Guidelines for Americans (PA Guidelines) on NAFLD are lacking. We performed a serial, cross‐sectional analysis among adults by using the 2007‐2016 US National Health and Nutrition Examination Survey. NAFLD and advanced fibrosis were defined by using various noninvasive panels. …

#Physical activity may not be associated with long‐term risk of #dementia and #Alzheimer’s disease
https://2medical.news/2021/02/22/physical-activity-may-not-be-associated-with-long%E2%80%90term-risk-of-dementia-and-alzheimers-disease/

While it is well established that physical activity is associated with reduced risk of vascular and nonvascular outcomes as well as mortality, evidence on the association between physical activity and dementia is inconsistent. We aimed to assess the associations of physical activity with the risk of dementia and Alzheimer’s disease (AD). Material and methods We analysed data on 2394 apparently healthy men with good baseline …

#Physical Activity as a Critical Component of First-Line Treatment for Elevated Blood #Pressure or #Cholesterol: Who, What, and How?: A Scientific Statement From the American Heart Association

https://2medical.news/2021/06/08/physical-activity-as-a-critical-component-of-first-line-treatment-for-elevated-blood-pressure-or-cholesterol-who-what-and-how-a-scientific-statement-from-the-american-heart-association/

Elucidating regulatory processes of intense #physical activity by multi-omics analysis

https://2medical.news/2023/11/29/elucidating-regulatory-processes-of-intense-physical-activity-by-multi-omics-analysis/

Longitudinal Associations Between #Optimism and Objective Measures of #Physical Functioning in Women

https://2medical.news/2024/03/30/longitudinal-associations-between-optimism-and-objective-measures-of-physical-functioning-in-women/

Impact of #lifestyle moderate-to-vigorous #physical activity timing on #glycemic control in sedentary adults with #overweight/obesity and metabolic impairments

https://2medical.news/2024/07/06/impact-of-lifestyle-moderate-to-vigorous-physical-activity-timing-on-glycemic-control-in-sedentary-adults-with-overweight-obesity-and-metabolic-impairments/

National, regional, and global trends in insufficient #physical activity among adults from 2000 to 2022: a pooled analysis of 507 population-based surveys with 5·7 million participants

https://2medical.news/2024/07/09/national-regional-and-global-trends-in-insufficient-physical-activity-among-adults-from-2000-to-2022-a-pooled-analysis-of-507-population-based-surveys-with-5%C2%B77-million-participants/