Detecting #hepatitis B virus in surgical #smoke emitted during laparoscopic surgery

http://m.oem.bmj.com/content/early/2016/08/02/oemed-2016-103724

Conclusions HBV is detectable in surgical smoke. This study provides preliminary data in the investigation of airborne HBV infection.

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Secondhand #Smoke and #CKD

https://cjasn.asnjournals.org/content/early/2019/03/06/CJN.09540818

Active smoking is associated with higher risk of various diseases. However, the risk of CKD development in nonsmokers exposed to secondhand smoke is not well elucidated

The mean age of participants was 53 years, and 75% were women. Prevalent CKD was observed in 231 (1.8%), 64 (1.7%), and 2280 (2.0%) participants in the ≥3 days per week, <3 days per week, and no exposure groups. The odds ratio (OR) of prevalent CKD was significantly higher in the groups exposed to secondhand smoke than the no exposure group (<3 days per week: OR, 1.72; 95% confidence interval [95% CI], 1.30 to 2.27; and ≥3 days per week: OR, 1.44; 95% CI, 1.22 to 1.70). During a mean follow-up of 104 months, CKD occurred in 319 (16%) participants. Multivariable Cox analysis revealed that the risk for CKD development was higher in participants exposed to secondhand smoke than the no exposure group (<3 days per week: hazard ratio, 1.59; 95% CI, 0.96 to 2.65; and ≥3 days per week: hazard ratio, 1.66; 95% CI, 1.03 to 2.67).

Conclusions Exposure to secondhand smoke was associated with a higher prevalence of CKD as well as development of incident CKD.

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Childhood Tobacco Smoke Exposure and Risk of Atrial #Fibrillation in Adulthood

Of 2,816 Offspring cohort participants with at least 1 parent in the Original cohort, 82% were exposed to parental smoking. For every pack/day increase in parental smoking, there was an 18% increase in offspring AF incidence (adjusted hazard ratio [HR]: 1.18; 95% confidence interval [CI]: 1.00 to 1.39; p = 0.04). Additionally, parental smoking was a risk factor for offspring smoking (adjusted odds ratio [OR]: 1.34; 95% CI: 1.17 to 1.54; p < 0.001). Offspring smoking mediated 17% (95% CI: 1.5% to 103.3%) of the relationship between parental smoking and offspring AF.

Conclusions Childhood secondhand #smoke exposure predicted increased risk for adulthood #AF after adjustment for AF risk factors. Some of this relationship may be mediated by a greater propensity among offspring of smoking parents to smoke themselves. These findings highlight potential new pathways for AF risk that begin during childhood, offering new evidence to motivate smoking avoidance and cessation

http://www.onlinejacc.org/content/74/13/1658

Human transport of thirdhand tobacco #smoke: A prominent source of hazardous air pollutants into indoor nonsmoking environments
https://2medical.news/2020/03/11/human-transport-of-thirdhand-tobacco-smoke-a-prominent-source-of-hazardous-air-pollutants-into-indoor-nonsmoking-environments/

The contamination of indoor nonsmoking environments with thirdhand smoke (THS) is an important, poorly understood public health concern. Real-time THS off-gassing from smokers into a nonsmoking movie theater was observed with online and offline high-resolution mass spectrometry. Prominent emission events of THS tracers (e.g., 2,5-dimethylfuran, 2-methylfuran, and acetonitrile) and other tobacco-related volatile organic compounds (VOCs) coincided with the arrival of certain moviegoers and left residual …

Cigarette #smoke exposure and inflammatory signaling increase the expression of the #SARS-CoV-2 receptor ACE2 in the respiratory tract
https://2medical.news/2020/05/31/cigarette-smoke-exposure-and-inflammatory-signaling-increase-the-expression-of-the-sars-cov-2-receptor-ace2-in-the-respiratory-tract/

Abstract The factors mediating fatal SARS-CoV-2 infections are poorly understood. Here, we show that cigarette smoke causes a dose-dependent upregulation of Angiotensin Converting Enzyme 2 (ACE2), the SARS-CoV-2 receptor, in rodent and human lungs. Using single-cell sequencing data, we demonstrate that ACE2 is expressed in a subset of secretory cells in the respiratory tract. Chronic smoke exposure triggers the expansion of this cell population and …

The contribution of secondhand tobacco #smoke to blood #lead levels in US children and adolescents: a cross-sectional analysis of NHANES 2015–2018

https://2medical.news/2023/08/26/the-contribution-of-secondhand-tobacco-smoke-to-blood-lead-levels-in-us-children-and-adolescents-a-cross-sectional-analysis-of-nhanes-2015-2018/