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Aldo Lorenzetti M.D, Internal Medicine & Hepatology, Milano - SIMEDET Delegate
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Natural history of acute #kidney disease in patients with #cirrhosis
https://2medical.news/2020/09/17/natural-history-of-acute-kidney-disease-in-patients-with-cirrhosis/

In 2012, KDIGO group proposed new definitions for Acute Kidney Injury (AKI), Acute Kidney Disease (AKD) and Chronic Kidney Disease (CKD). According to the definition adapted by the International Club of Ascites (ICA), AKI has been extensively investigated in patients with cirrhosis. On the contrary, there are currently no data on the epidemiology and clinical outcome of AKD in these patients. The aim of the …
#Dapagliflozin in Patients with Chronic #Kidney Disease
https://2medical.news/2020/09/28/dapagliflozin-in-patients-with-chronic-kidney-disease/

Patients with chronic kidney disease have a high risk of adverse kidney and cardiovascular outcomes. The effect of dapagliflozin in patients with chronic kidney disease, with or without type 2 diabetes, is not known.. ..The independent data monitoring committee recommended stopping the trial because of efficacy. Over a median of 2.4 years, a primary outcome event occurred in 197 of 2152 participants (9.2%) in the …
#Hypoalbuminemia is associated with increased risk of acute #kidney injury in hospitalized patients: A meta-analysis
https://2medical.news/2020/10/24/hypoalbuminemia-is-associated-with-increased-risk-of-acute-kidney-injury-in-hospitalized-patients-a-meta-analysis/

Highlights • Each 1.0 g/dL of serum albumin decrement was associated with increased odds of AKI (OR 1.685; 95% CI, 1.302–2.179). • The risk factors for AKI in hypoalbuminemic patients include 1) age ≥ 70 years and 2) baseline serum albumin level > 3.2 g/dL. • The association between hypoalbuminemia and overall mortality from AKI remained inconclusive as there was potential publication bias. https://bit.ly/2HeU31v
Low High‐Sensitivity C‐ #Reactive Protein Level in Korean Patients With Chronic #Kidney Disease and Its Predictive Significance for Cardiovascular Events, Mortality, and Adverse Kidney Outcomes: Results From KNOW‐CKD
https://2medical.news/2020/11/01/low-high%E2%80%90sensitivity-c%E2%80%90-reactive-protein-level-in-korean-patients-with-chronic-kidney-disease-and-its-predictive-significance-for-cardiovascular-events-mortality-and-adverse-kidney/

Inflammation levels are lower in East Asians than in Western people. We studied the association between high‐sensitivity hs‐CRP (C‐reactive protein) and adverse outcomes in Korean patients with chronic kidney disease. Methods and Results We included 2018 participants from the KNOW‐CKD (Korean Cohort Study for Outcome in Patients With Chronic Kidney Disease) between April 2011 and February 2016. The primary outcome was a composite of extended …
The #Kidney Disease: Improving Global Outcomes (KDIGO) 2020 Clinical Practice Guideline for #Diabetes Management in Chronic Kidney Disease (CKD)
https://2medical.news/2020/11/14/the-kidney-disease-improving-global-outcomes-kdigo-2020-clinical-practice-guideline-for-diabetes-management-in-chronic-kidney-disease-ckd/

Here attached you may find the takeaways of the guidelines for patients and for clinicians. takeaways for patients: https://kdigo.org/wp-content/uploads/2018/03/Top-10-Takeaways-Patients.pdf takeaways for clinicians: https://kdigo.org/wp-content/uploads/2018/03/Top-10-Takeaways-Clinicians.pdf