Association Between the Gut #Microbiota and Blood #Pressure in a Population Cohort of 6953 Individuals
https://2medical.news/2020/08/17/association-between-the-gut-microbiota-and-blood-pressure-in-a-population-cohort-of-6953-individuals/
Several small‐scale animal studies have suggested that gut microbiota and blood pressure (BP) are linked. However, results from human studies remain scarce and conflicting. We wanted to elucidate the multivariable‐adjusted association between gut metagenome and BP in a large, representative, well‐phenotyped population sample. We performed a focused analysis to examine the previously reported inverse associations between sodium intake and Lactobacillus abundance and between Lactobacillus abundance …
https://2medical.news/2020/08/17/association-between-the-gut-microbiota-and-blood-pressure-in-a-population-cohort-of-6953-individuals/
Several small‐scale animal studies have suggested that gut microbiota and blood pressure (BP) are linked. However, results from human studies remain scarce and conflicting. We wanted to elucidate the multivariable‐adjusted association between gut metagenome and BP in a large, representative, well‐phenotyped population sample. We performed a focused analysis to examine the previously reported inverse associations between sodium intake and Lactobacillus abundance and between Lactobacillus abundance …
Vitamin #D for treatment of non‐alcoholic #fatty liver disease detected by transient elastography: A randomized, double‐blind, placebo‐controlled trial
https://2medical.news/2020/08/18/vitamin-d-for-treatment-of-non%E2%80%90alcoholic-fatty-liver-disease-detected-by-transient-elastography-a-randomized-double%E2%80%90blind-placebo%E2%80%90controlled-trial/
To evaluate the effects of vitamin D on transient elastography (TE, FibroScan) indices of liver steatosis (controlled attenuation parameter [CAP]) and fibrosis (liver stiffness measurement [LSM]) in adults with non‐alcoholic fatty liver disease (NAFLD).. ..Both CAP and LSM gradually decreased in vitamin D‐treated patients and slightly increased in the placebo arm. Vitamin D was superior to placebo for both primary outcomes (mean differences in CAP …
https://2medical.news/2020/08/18/vitamin-d-for-treatment-of-non%E2%80%90alcoholic-fatty-liver-disease-detected-by-transient-elastography-a-randomized-double%E2%80%90blind-placebo%E2%80%90controlled-trial/
To evaluate the effects of vitamin D on transient elastography (TE, FibroScan) indices of liver steatosis (controlled attenuation parameter [CAP]) and fibrosis (liver stiffness measurement [LSM]) in adults with non‐alcoholic fatty liver disease (NAFLD).. ..Both CAP and LSM gradually decreased in vitamin D‐treated patients and slightly increased in the placebo arm. Vitamin D was superior to placebo for both primary outcomes (mean differences in CAP …
CMS121, a fatty acid synthase inhibitor, protects against excess lipid peroxidation and inflammation and alleviates cognitive loss in a transgenic mouse model of #Alzheimer’s disease
https://2medical.news/2020/08/19/cms121-a-fatty-acid-synthase-inhibitor-protects-against-excess-lipid-peroxidation-and-inflammation-and-alleviates-cognitive-loss-in-a-transgenic-mouse-model-of-alzheimers-disease/
The oxidative degradation of lipids has been shown to be implicated in the progression of several neurodegenerative diseases and modulating lipid peroxidation may be efficacious for treating Alzheimer’s disease (AD). This hypothesis is strengthened by recent findings suggesting that oxytosis/ferroptosis, a cell death process characterized by increased lipid peroxidation, plays an important role in AD-related toxicities. CMS121 is a small molecule developed against these aspects …
https://2medical.news/2020/08/19/cms121-a-fatty-acid-synthase-inhibitor-protects-against-excess-lipid-peroxidation-and-inflammation-and-alleviates-cognitive-loss-in-a-transgenic-mouse-model-of-alzheimers-disease/
The oxidative degradation of lipids has been shown to be implicated in the progression of several neurodegenerative diseases and modulating lipid peroxidation may be efficacious for treating Alzheimer’s disease (AD). This hypothesis is strengthened by recent findings suggesting that oxytosis/ferroptosis, a cell death process characterized by increased lipid peroxidation, plays an important role in AD-related toxicities. CMS121 is a small molecule developed against these aspects …
An electrophysiological marker of #arousal level in humans
https://2medical.news/2020/08/20/an-electrophysiological-marker-of-arousal-level-in-humans/
Deep non-rapid eye movement sleep (NREM) and general anesthesia with propofol are prominent states of reduced arousal linked to the occurrence of synchronized oscillations in the electroencephalogram (EEG). Although rapid eye movement (REM) sleep is also associated with diminished arousal levels, it is characterized by a desynchronized, ‘wake-like’ EEG. This observation implies that reduced arousal states are not necessarily only defined by synchronous oscillatory activity. …
https://2medical.news/2020/08/20/an-electrophysiological-marker-of-arousal-level-in-humans/
Deep non-rapid eye movement sleep (NREM) and general anesthesia with propofol are prominent states of reduced arousal linked to the occurrence of synchronized oscillations in the electroencephalogram (EEG). Although rapid eye movement (REM) sleep is also associated with diminished arousal levels, it is characterized by a desynchronized, ‘wake-like’ EEG. This observation implies that reduced arousal states are not necessarily only defined by synchronous oscillatory activity. …
Increasing Emergency Department Visits for #Mental Health Conditions in the United States
https://2medical.news/2020/08/21/increasing-emergency-department-visits-for-mental-health-conditions-in-the-united-states/
..Nationally representative samples of ED visits in the United States were assessed using a repeated cross-sectional analysis of National Hospital Ambulatory Medical Care Survey data. This study used diagnoses associated with each ED visit to identify changes in proportions in mental health diagnostic categories (psychiatric diagnoses only, substance use–related diagnoses only, or both, based on ICD-9-CM or ICD-10-CM criteria). These trends were further examined by …
https://2medical.news/2020/08/21/increasing-emergency-department-visits-for-mental-health-conditions-in-the-united-states/
..Nationally representative samples of ED visits in the United States were assessed using a repeated cross-sectional analysis of National Hospital Ambulatory Medical Care Survey data. This study used diagnoses associated with each ED visit to identify changes in proportions in mental health diagnostic categories (psychiatric diagnoses only, substance use–related diagnoses only, or both, based on ICD-9-CM or ICD-10-CM criteria). These trends were further examined by …
Clinical Course and Molecular Viral Shedding Among Asymptomatic and Symptomatic Patients With #SARS-CoV-2 Infection in a Community Treatment Center in the Republic of Korea
https://2medical.news/2020/08/22/clinical-course-and-molecular-viral-shedding-among-asymptomatic-and-symptomatic-patients-with-sars-cov-2-infection-in-a-community-treatment-center-in-the-republic-of-korea/
There is limited information about the clinical course and viral load in asymptomatic patients infected with severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2).. Epidemiologic, demographic, and laboratory data were collected and analyzed. Attending health care personnel carefully identified patients’ symptoms during isolation. The decision to release an individual from isolation was based on the results of reverse transcription–polymerase chain reaction (RT-PCR) assay from upper respiratory …
https://2medical.news/2020/08/22/clinical-course-and-molecular-viral-shedding-among-asymptomatic-and-symptomatic-patients-with-sars-cov-2-infection-in-a-community-treatment-center-in-the-republic-of-korea/
There is limited information about the clinical course and viral load in asymptomatic patients infected with severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2).. Epidemiologic, demographic, and laboratory data were collected and analyzed. Attending health care personnel carefully identified patients’ symptoms during isolation. The decision to release an individual from isolation was based on the results of reverse transcription–polymerase chain reaction (RT-PCR) assay from upper respiratory …
#Migraine, obesity and body #fat distribution – a population-based study
https://2medical.news/2020/08/23/migraine-obesity-and-body-fat-distribution-a-population-based-study/
Obesity has been linked to an increased prevalence of migraine, and to increased migraine attack frequency, but several questions are left unanswered by previous studies. We examined the relationship between obesity and headache in a large, population-based study where we could take into account body fat distribution, migraine subtypes and tension-type headache.. ..Both total body obesity (TBO) and abdominal obesity (AO) were associated with a …
https://2medical.news/2020/08/23/migraine-obesity-and-body-fat-distribution-a-population-based-study/
Obesity has been linked to an increased prevalence of migraine, and to increased migraine attack frequency, but several questions are left unanswered by previous studies. We examined the relationship between obesity and headache in a large, population-based study where we could take into account body fat distribution, migraine subtypes and tension-type headache.. ..Both total body obesity (TBO) and abdominal obesity (AO) were associated with a …
Effects of #Diet versus Gastric #Bypass on Metabolic Function in Diabetes
https://2medical.news/2020/08/24/effects-of-diet-versus-gastric-bypass-on-metabolic-function-in-diabetes/
Some studies have suggested that in people with type 2 diabetes, Roux-en-Y gastric bypass has therapeutic effects on metabolic function that are independent of weight loss.. ..Weight loss was associated with increases in mean suppression of glucose production from baseline, by 7.04 μmol per kilogram of fat-free mass per minute (95% confidence interval [CI], 4.74 to 9.33) in the diet group and by 7.02 μmol …
https://2medical.news/2020/08/24/effects-of-diet-versus-gastric-bypass-on-metabolic-function-in-diabetes/
Some studies have suggested that in people with type 2 diabetes, Roux-en-Y gastric bypass has therapeutic effects on metabolic function that are independent of weight loss.. ..Weight loss was associated with increases in mean suppression of glucose production from baseline, by 7.04 μmol per kilogram of fat-free mass per minute (95% confidence interval [CI], 4.74 to 9.33) in the diet group and by 7.02 μmol …
Effectiveness of #honey for symptomatic relief in upper #respiratory tract infections: a systematic review and meta-analysis
https://2medical.news/2020/08/25/effectiveness-of-honey-for-symptomatic-relief-in-upper-respiratory-tract-infections-a-systematic-review-and-meta-analysis/
Antibiotic over prescription for upper respiratory tract infections (URTIs) in primary care exacerbates antimicrobial resistance. There is a need for effective alternatives to antibiotic prescribing. Honey is a lay remedy for URTIs, and has an emerging evidence base for its use. Honey has antimicrobial properties, and guidelines recommended honey for acute cough in children.. ..We identified 1345 unique records, and 14 studies were included. Overall …
https://2medical.news/2020/08/25/effectiveness-of-honey-for-symptomatic-relief-in-upper-respiratory-tract-infections-a-systematic-review-and-meta-analysis/
Antibiotic over prescription for upper respiratory tract infections (URTIs) in primary care exacerbates antimicrobial resistance. There is a need for effective alternatives to antibiotic prescribing. Honey is a lay remedy for URTIs, and has an emerging evidence base for its use. Honey has antimicrobial properties, and guidelines recommended honey for acute cough in children.. ..We identified 1345 unique records, and 14 studies were included. Overall …
Atypical Femur #Fracture Risk versus Fragility Fracture Prevention with #Bisphosphonates
https://2medical.news/2020/08/26/atypical-femur-fracture-risk-versus-fragility-fracture-prevention-with-bisphosphonates/
Bisphosphonates are effective in reducing hip and osteoporotic fractures. However, concerns about atypical femur fractures have contributed to substantially decreased bisphosphonate use, and the incidence of hip fractures may be increasing. Important uncertainties remain regarding the association between atypical femur fractures and bisphosphonates and other risk factors.. ..Among 196,129 women, 277 atypical femur fractures occurred. After multivariable adjustment, the risk of atypical fracture increased with …
https://2medical.news/2020/08/26/atypical-femur-fracture-risk-versus-fragility-fracture-prevention-with-bisphosphonates/
Bisphosphonates are effective in reducing hip and osteoporotic fractures. However, concerns about atypical femur fractures have contributed to substantially decreased bisphosphonate use, and the incidence of hip fractures may be increasing. Important uncertainties remain regarding the association between atypical femur fractures and bisphosphonates and other risk factors.. ..Among 196,129 women, 277 atypical femur fractures occurred. After multivariable adjustment, the risk of atypical fracture increased with …
Co‐occurrence of #antibiotic, biocide, and heavy #metal resistance genes in bacteria from metal and radionuclide contaminated soils at the Savannah River Site
https://2medical.news/2020/08/27/co%E2%80%90occurrence-of-antibiotic-biocide-and-heavy-metal-resistance-genes-in-bacteria-from-metal-and-radionuclide-contaminated-soils-at-the-savannah-river-site/
Contaminants such as heavy metals may contribute to the dissemination of antimicrobial resistance (AMR) by enriching resistance gene determinants via co‐selection mechanisms. In the present study, a survey was performed on soils collected from four areas at the Savannah River Site (SRS), South Carolina, USA, with varying contaminant profiles: relatively pristine (Upper Three Runs), heavy metals (Ash Basins), radionuclides (Pond B) and heavy metal and …
https://2medical.news/2020/08/27/co%E2%80%90occurrence-of-antibiotic-biocide-and-heavy-metal-resistance-genes-in-bacteria-from-metal-and-radionuclide-contaminated-soils-at-the-savannah-river-site/
Contaminants such as heavy metals may contribute to the dissemination of antimicrobial resistance (AMR) by enriching resistance gene determinants via co‐selection mechanisms. In the present study, a survey was performed on soils collected from four areas at the Savannah River Site (SRS), South Carolina, USA, with varying contaminant profiles: relatively pristine (Upper Three Runs), heavy metals (Ash Basins), radionuclides (Pond B) and heavy metal and …
Efficacy and safety of gastrointestinal #bleeding prophylaxis in critically #ill patients: an updated systematic review and network meta-analysis of randomized trials
https://2medical.news/2020/08/28/efficacy-and-safety-of-gastrointestinal-bleeding-prophylaxis-in-critically-ill-patients-an-updated-systematic-review-and-network-meta-analysis-of-randomized-trials/
Motivated by a new randomized trial (the PEPTIC trial) that raised the issue of an increase in mortality with proton pump inhibitors (PPIs) relative to histamine-2 receptor antagonists (H2RAs), we updated our prior systematic review and network meta-analysis (NMA) addressing the impact of pharmacological gastrointestinal bleeding prophylaxis in critically ill patients. Seventy-four trials enrolling 39 569 patients proved eligible. Both PPIs (risk ratio (RR) 1.03, …
https://2medical.news/2020/08/28/efficacy-and-safety-of-gastrointestinal-bleeding-prophylaxis-in-critically-ill-patients-an-updated-systematic-review-and-network-meta-analysis-of-randomized-trials/
Motivated by a new randomized trial (the PEPTIC trial) that raised the issue of an increase in mortality with proton pump inhibitors (PPIs) relative to histamine-2 receptor antagonists (H2RAs), we updated our prior systematic review and network meta-analysis (NMA) addressing the impact of pharmacological gastrointestinal bleeding prophylaxis in critically ill patients. Seventy-four trials enrolling 39 569 patients proved eligible. Both PPIs (risk ratio (RR) 1.03, …
Risk of #amputation with #canagliflozin across categories of age and cardiovascular risk in three US nationwide databases: cohort study
https://2medical.news/2020/08/29/risk-of-amputation-with-canagliflozin-across-categories-of-age-and-cardiovascular-risk-in-three-us-nationwide-databases-cohort-study/
..Results Across the three databases, 310 840 propensity score matched adults who started canagliflozin or a GLP-1 agonist were identified. The hazard ratio and rate difference per 1000 person years for amputation in adults receiving canagliflozin compared with a GLP-1 agonist for each group was: group 1, hazard ratio 1.09 (95% confidence interval 0.83 to 1.43), rate difference 0.12 (−0.31 to 0.55); group 2, hazard ratio …
https://2medical.news/2020/08/29/risk-of-amputation-with-canagliflozin-across-categories-of-age-and-cardiovascular-risk-in-three-us-nationwide-databases-cohort-study/
..Results Across the three databases, 310 840 propensity score matched adults who started canagliflozin or a GLP-1 agonist were identified. The hazard ratio and rate difference per 1000 person years for amputation in adults receiving canagliflozin compared with a GLP-1 agonist for each group was: group 1, hazard ratio 1.09 (95% confidence interval 0.83 to 1.43), rate difference 0.12 (−0.31 to 0.55); group 2, hazard ratio …
Modeling the Onset of #Symptoms of #COVID-19
https://2medical.news/2020/08/30/modeling-the-onset-of-symptoms-of-covid-19/
COVID-19 is a pandemic viral disease with catastrophic global impact. This disease is more contagious than influenza such that cluster outbreaks occur frequently. If patients with symptoms quickly underwent testing and contact tracing, these outbreaks could be contained. Unfortunately, COVID-19 patients have symptoms similar to other common illnesses. Here, we hypothesize the order of symptom occurrence could help patients and medical professionals more quickly distinguish …
https://2medical.news/2020/08/30/modeling-the-onset-of-symptoms-of-covid-19/
COVID-19 is a pandemic viral disease with catastrophic global impact. This disease is more contagious than influenza such that cluster outbreaks occur frequently. If patients with symptoms quickly underwent testing and contact tracing, these outbreaks could be contained. Unfortunately, COVID-19 patients have symptoms similar to other common illnesses. Here, we hypothesize the order of symptom occurrence could help patients and medical professionals more quickly distinguish …
Vitamin #D receptor is overexpressed in the duodenum of patients with #irritable bowel syndrome
https://2medical.news/2020/08/31/vitamin-d-receptor-is-overexpressed-in-the-duodenum-of-patients-with-irritable-bowel-syndrome/
Irritable bowel syndrome (IBS) is one of the most common functional gastrointestinal disorders and bile acids are thought to be associated with the pathogenesis of IBS. Bile acid receptors are expressed on intestinal epithelial cells. However, no study has assessed bile acid receptor proteins in IBS. Therefore, we examined the intestinal mucosal expression of bile acid receptors in patients with IBS.. Intestinal biopsies were performed …
https://2medical.news/2020/08/31/vitamin-d-receptor-is-overexpressed-in-the-duodenum-of-patients-with-irritable-bowel-syndrome/
Irritable bowel syndrome (IBS) is one of the most common functional gastrointestinal disorders and bile acids are thought to be associated with the pathogenesis of IBS. Bile acid receptors are expressed on intestinal epithelial cells. However, no study has assessed bile acid receptor proteins in IBS. Therefore, we examined the intestinal mucosal expression of bile acid receptors in patients with IBS.. Intestinal biopsies were performed …
The change in #kidney function was associated with #carotid artery plaque in a community-based population: a cohort study
https://2medical.news/2020/09/01/the-change-in-kidney-function-was-associated-with-carotid-artery-plaque-in-a-community-based-population-a-cohort-study/
We performed the current study to evaluate the association between dynamic change in estimated glomerular filtration rate (eGFR) and the risk of carotid artery plaque (CAP) in a community-based population A total number of 37,093 Chinese adults (21,790 men and 15,303 women, aged 42.6±11.6 years) free of chronic kidney diseases were enrolled. The change in eGFR was calculated based on two measurements in 2013 and …
https://2medical.news/2020/09/01/the-change-in-kidney-function-was-associated-with-carotid-artery-plaque-in-a-community-based-population-a-cohort-study/
We performed the current study to evaluate the association between dynamic change in estimated glomerular filtration rate (eGFR) and the risk of carotid artery plaque (CAP) in a community-based population A total number of 37,093 Chinese adults (21,790 men and 15,303 women, aged 42.6±11.6 years) free of chronic kidney diseases were enrolled. The change in eGFR was calculated based on two measurements in 2013 and …
American Academy of Pediatrics – Section on Pediatric #Pulmonology and #Sleep Medicine
https://2medical.news/2020/09/01/american-academy-of-pediatrics-section-on-pediatric-pulmonology-and-sleep-medicine/
1. Avoid stepping up asthma therapy (adding new drugs or going to higher doses) before assessing adherence, appropriateness of device, and technique with current asthma medications. 2. Do not use LABA/steroid combination drugs as initial therapy for intermittent or mild persistent asthma. 3. Avoid administering nebulized medications by “blow by,” or placing the mask or nebulizer tubing near the child’s nose and mouth rather than …
https://2medical.news/2020/09/01/american-academy-of-pediatrics-section-on-pediatric-pulmonology-and-sleep-medicine/
1. Avoid stepping up asthma therapy (adding new drugs or going to higher doses) before assessing adherence, appropriateness of device, and technique with current asthma medications. 2. Do not use LABA/steroid combination drugs as initial therapy for intermittent or mild persistent asthma. 3. Avoid administering nebulized medications by “blow by,” or placing the mask or nebulizer tubing near the child’s nose and mouth rather than …
Meta-analysis of Effectiveness of #Statins in Patients with Severe #COVID-19
https://2medical.news/2020/09/02/meta-analysis-of-effectiveness-of-statins-in-patients-with-severe-covid-19/
..Our Pubmed search yielded 274 potential studies. After deduplication and application of the eligibility criteria, four studies with a total of 8,990 COVID-19 patients were included for meta-analysis. Except for Yan et al. which is of moderate quality (5/9), other studies are of good quality (at least 7/9). Study characteristics are provided in Table 1. The pooled analysis revealed a significantly reduced hazard for fatal …
https://2medical.news/2020/09/02/meta-analysis-of-effectiveness-of-statins-in-patients-with-severe-covid-19/
..Our Pubmed search yielded 274 potential studies. After deduplication and application of the eligibility criteria, four studies with a total of 8,990 COVID-19 patients were included for meta-analysis. Except for Yan et al. which is of moderate quality (5/9), other studies are of good quality (at least 7/9). Study characteristics are provided in Table 1. The pooled analysis revealed a significantly reduced hazard for fatal …
COVID-19 Update: FDA Broadens Emergency Use Authorization for Veklury (#remdesivir) to Include All Hospitalized Patients for Treatment of #COVID-19
https://2medical.news/2020/09/02/covid-19-update-fda-broadens-emergency-use-authorization-for-veklury-remdesivir-to-include-all-hospitalized-patients-for-treatment-of-covid-19/
…based on the Agency’s ongoing review of the EUA, including its review of the totality of scientific information now available, the FDA has determined that it is reasonable to believe Veklury may be effective for the treatment of suspected or laboratory-confirmed COVID-19 in all hospitalized adult and pediatric patients. The Agency’s review has also concluded that the known and potential benefits of Veklury outweigh the …
https://2medical.news/2020/09/02/covid-19-update-fda-broadens-emergency-use-authorization-for-veklury-remdesivir-to-include-all-hospitalized-patients-for-treatment-of-covid-19/
…based on the Agency’s ongoing review of the EUA, including its review of the totality of scientific information now available, the FDA has determined that it is reasonable to believe Veklury may be effective for the treatment of suspected or laboratory-confirmed COVID-19 in all hospitalized adult and pediatric patients. The Agency’s review has also concluded that the known and potential benefits of Veklury outweigh the …
#Aspirin with or without #Clopidogrel after Transcatheter Aortic- #Valve Implantation
https://2medical.news/2020/09/03/aspirin-with-or-without-clopidogrel-after-transcatheter-aortic-valve-implantation/
The effect of single as compared with dual antiplatelet treatment on bleeding and thromboembolic events after transcatheter aortic-valve implantation (TAVI) in patients who do not have an indication for long-term anticoagulation has not been well studied.. ..A total of 331 patients were assigned to receive aspirin alone and 334 were assigned to receive aspirin plus clopidogrel. A bleeding event occurred in 50 patients (15.1%) receiving …
https://2medical.news/2020/09/03/aspirin-with-or-without-clopidogrel-after-transcatheter-aortic-valve-implantation/
The effect of single as compared with dual antiplatelet treatment on bleeding and thromboembolic events after transcatheter aortic-valve implantation (TAVI) in patients who do not have an indication for long-term anticoagulation has not been well studied.. ..A total of 331 patients were assigned to receive aspirin alone and 334 were assigned to receive aspirin plus clopidogrel. A bleeding event occurred in 50 patients (15.1%) receiving …
Increased rates of #eating disorders and their symptoms in women with major #depressive disorder and #anxiety disorders
https://2medical.news/2020/09/03/increased-rates-of-eating-disorders-and-their-symptoms-in-women-with-major-depressive-disorder-and-anxiety-disorders/
Individuals with eating disorders (EDs) have increased rates of major depressive disorder (MDD) and anxiety disorders. Yet, few studies have investigated rates of EDs and their symptoms in individuals presenting with MDD/anxiety disorders. Identifying potential disordered eating in people with MDD/anxiety disorders is important because even subclinical disordered eating is associated with reduced quality of life, and undiagnosed eating pathology may hinder treatment progress for …
https://2medical.news/2020/09/03/increased-rates-of-eating-disorders-and-their-symptoms-in-women-with-major-depressive-disorder-and-anxiety-disorders/
Individuals with eating disorders (EDs) have increased rates of major depressive disorder (MDD) and anxiety disorders. Yet, few studies have investigated rates of EDs and their symptoms in individuals presenting with MDD/anxiety disorders. Identifying potential disordered eating in people with MDD/anxiety disorders is important because even subclinical disordered eating is associated with reduced quality of life, and undiagnosed eating pathology may hinder treatment progress for …