Low #Zinc Levels at Admission Associates with Poor Clinical Outcomes in #SARS-CoV-2 Infection
https://2medical.news/2021/03/11/low-zinc-levels-at-admission-associates-with-poor-clinical-outcomes-in-sars-cov-2-infection/
Background: Zinc is an essential micronutrient that impacts host–pathogen interplay at infection. Zinc balances immune responses, and also has a proven direct antiviral action against some viruses. Importantly, zinc deficiency (ZD) is a common condition in elderly and individuals with chronic diseases, two groups with an increased risk for severe severe coronavirus disease 2019 (COVID-19) outcomes. We hypothesize that serum zinc content (SZC) influences COVID-19 …
https://2medical.news/2021/03/11/low-zinc-levels-at-admission-associates-with-poor-clinical-outcomes-in-sars-cov-2-infection/
Background: Zinc is an essential micronutrient that impacts host–pathogen interplay at infection. Zinc balances immune responses, and also has a proven direct antiviral action against some viruses. Importantly, zinc deficiency (ZD) is a common condition in elderly and individuals with chronic diseases, two groups with an increased risk for severe severe coronavirus disease 2019 (COVID-19) outcomes. We hypothesize that serum zinc content (SZC) influences COVID-19 …
Assessment of protection against #reinfection with #SARS-CoV-2 among 4 million PCR-tested individuals in Denmark in 2020: a population-level observational study
https://2medical.news/2021/03/19/assessment-of-protection-against-reinfection-with-sars-cov-2-among-4-million-pcr-tested-individuals-in-denmark-in-2020-a-population-level-observational-study/
The degree to which infection with SARS-CoV-2 confers protection towards subsequent reinfection is not well described. In 2020, as part of Denmark’s extensive, free-of-charge PCR-testing strategy, approximately 4 million individuals (69% of the population) underwent 10·6 million tests. Using these national PCR-test data from 2020, we estimated protection towards repeat infection with SARS-CoV-2. Methods In this population-level observational study, we collected individual-level data on patients …
https://2medical.news/2021/03/19/assessment-of-protection-against-reinfection-with-sars-cov-2-among-4-million-pcr-tested-individuals-in-denmark-in-2020-a-population-level-observational-study/
The degree to which infection with SARS-CoV-2 confers protection towards subsequent reinfection is not well described. In 2020, as part of Denmark’s extensive, free-of-charge PCR-testing strategy, approximately 4 million individuals (69% of the population) underwent 10·6 million tests. Using these national PCR-test data from 2020, we estimated protection towards repeat infection with SARS-CoV-2. Methods In this population-level observational study, we collected individual-level data on patients …
Lower risk of #SARS-CoV2 infection in individuals with severe #mental disorders on #antipsychotic treatment: A retrospective epidemiological study in a representative Spanish population
https://2medical.news/2021/04/20/lower-risk-of-sars-cov2-infection-in-individuals-with-severe-mental-disorders-on-antipsychotic-treatment-a-retrospective-epidemiological-study-in-a-representative-spanish-population/
To the editors, The population with severe mental disorders (SMD) is a medically and socially vulnerable group for a worse outcome in COVID-19. This population has been identified as high-risk group for COVID-19 due to lower awareness of risk, higher prevalence of cognitive impairment and who have limitations to maintain adequate barriers against virus propagation such as living in long-term care facilities, and people with …
https://2medical.news/2021/04/20/lower-risk-of-sars-cov2-infection-in-individuals-with-severe-mental-disorders-on-antipsychotic-treatment-a-retrospective-epidemiological-study-in-a-representative-spanish-population/
To the editors, The population with severe mental disorders (SMD) is a medically and socially vulnerable group for a worse outcome in COVID-19. This population has been identified as high-risk group for COVID-19 due to lower awareness of risk, higher prevalence of cognitive impairment and who have limitations to maintain adequate barriers against virus propagation such as living in long-term care facilities, and people with …
Face #masks effectively limit the probability of #SARS-CoV-2 transmission
https://2medical.news/2021/05/22/face-masks-effectively-limit-the-probability-of-sars-cov-2-transmission/
https://2medical.news/2021/05/22/face-masks-effectively-limit-the-probability-of-sars-cov-2-transmission/
2Medical.News
Face #masks effectively limit the probability of #SARS-CoV-2 transmission
Airborne transmission by droplets and aerosols is important for the spread of viruses. Face masks are a well-established preventive measure, but their effectiveness for mitigating SARS-CoV-2 transm…
First case of postmortem study in a patient vaccinated against #SARS-CoV-2
https://2medical.news/2021/06/15/first-case-of-postmortem-study-in-a-patient-vaccinated-against-sars-cov-2/
https://2medical.news/2021/06/15/first-case-of-postmortem-study-in-a-patient-vaccinated-against-sars-cov-2/
2Medical.News
First case of postmortem study in a patient vaccinated against #SARS-CoV-2
Highlights•We report on a patient with a single dose of vaccine against SARS-CoV-2. •He developed relevant serum titer levels but died 4 weeks later. •By postmortem molecular mapping, we found vira…
Multiple #SARS-CoV-2 variants escape neutralization by #vaccine-induced humoral immunity
https://2medical.news/2021/06/21/multiple-sars-cov-2-variants-escape-neutralization-by-vaccine-induced-humoral-immunity/
https://2medical.news/2021/06/21/multiple-sars-cov-2-variants-escape-neutralization-by-vaccine-induced-humoral-immunity/
2Medical.News
Multiple #SARS-CoV-2 variants escape neutralization by #vaccine-induced humoral immunity
Vaccination elicits immune responses capable of potently neutralizing SARS-CoV-2. However, ongoing surveillance has revealed the emergence of variants harboring mutations in spike, the main target …
Dynamic innate immune response determines susceptibility to #SARS-CoV-2 infection and early replication kinetics
https://2medical.news/2021/06/23/dynamic-innate-immune-response-determines-susceptibility-to-sars-cov-2-infection-and-early-replication-kinetics/
https://2medical.news/2021/06/23/dynamic-innate-immune-response-determines-susceptibility-to-sars-cov-2-infection-and-early-replication-kinetics/
2Medical.News
Dynamic innate immune response determines susceptibility to #SARS-CoV-2 infection and early replication kinetics
Initial replication of SARS-CoV-2 in the upper respiratory tract is required to establish infection, and the replication levelcorrelates with the likelihood of viral transmission. Here, we examined…
Vaccine Breakthrough Infections with #SARS-CoV-2 Variants
https://2medical.news/2021/06/25/vaccine-breakthrough-infections-with-sars-cov-2-variants/
https://2medical.news/2021/06/25/vaccine-breakthrough-infections-with-sars-cov-2-variants/
2Medical.News
Vaccine Breakthrough Infections with #SARS-CoV-2 Variants
Emerging variants of severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2) are of clinical concern. In a cohort of 417 persons who had received the second dose of BNT162b2 (Pfizer–BioNTech) …
Acute and long-term disruption of #glycometabolic control after #SARS-CoV-2 infection
https://2medical.news/2021/06/29/acute-and-long-term-disruption-of-glycometabolic-control-after-sars-cov-2-infection/
https://2medical.news/2021/06/29/acute-and-long-term-disruption-of-glycometabolic-control-after-sars-cov-2-infection/
2Medical.News
Acute and long-term disruption of #glycometabolic control after #SARS-CoV-2 infection
Patients with coronavirus disease 2019 (COVID-19) are reported to have a greater prevalence of hyperglycaemia. Cytokine release as a consequence of severe acute respiratory syndrome coronavirus 2 i…
Common #dandelion (Taraxacum officinale) efficiently blocks the interaction between ACE2 cell surface receptor and #SARS-CoV-2 spike protein D614, mutants D614G, N501Y, K417N and E484K in vitro
https://2medical.news/2021/06/30/common-dandelion-taraxacum-officinale-efficiently-blocks-the-interaction-between-ace2-cell-surface-receptor-and-sars-cov-2-spike-protein-d614-mutants-d614g-n501y-k417n-and-e484k-in-vitro/
https://2medical.news/2021/06/30/common-dandelion-taraxacum-officinale-efficiently-blocks-the-interaction-between-ace2-cell-surface-receptor-and-sars-cov-2-spike-protein-d614-mutants-d614g-n501y-k417n-and-e484k-in-vitro/
2Medical.News
Common #dandelion (Taraxacum officinale) efficiently blocks the interaction between ACE2 cell surface receptor and #SARS-CoV-2…
bioRxiv posts many COVID19-related papers. A reminder: they have not been formally peer-reviewed and should not guide health-related behavior or be reported in the press as conclusive. On 11th Marc…