Oral #Contraceptive Use Dampens Physiological Adaptations to Sprint Interval #Training.

http://mobile.journals.lww.com/acsm-msse/_layouts/15/oaks.journals.mobile/articleviewer.aspx?year=9000&issue=00000&article=97334

SIT improved peak exercise responses in recreationally-active women. However, OC use dampened V[spacing dot above]O2peak and Q[spacing dot above]peak adaptation. A follow-up period indicated that OC users had spared V[spacing dot above]O2peak adaptations, suggesting that OC use may influence the time course of physiological training adaptations. Therefore, OC use should be verified, controlled for, and considered when interpreting physiological adaptations to exercise training in women.

High Intensity Interval #Training in #Heart Failure Patients with Reduced Ejection Fraction

http://circ.ahajournals.org/content/early/2017/01/19/CIRCULATIONAHA.116.022924

Small studies have suggested that high intensity interval training (HIIT) is superior to moderate continuous training (MCT) in reversing cardiac remodeling and increasing aerobic capacity in heart failure patients with reduced ejection fraction (HFrEF).
HIIT was not superior to MCT in changing left ventricular remodeling or aerobic capacity, and its feasibility remains unresolved in heart failure patients.

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#Dementia And Physical Activity (DAPA) trial of moderate to high intensity exercise #training for people with dementia: randomised controlled trial

https://www.bmj.com/content/361/bmj.k1675


The average age of participants was 77 (SD 7.9) years and 301/494 (61%) were men. By 12 months the mean ADAS-cog score had increased to 25.2 (SD 12.3) in the exercise arm and 23.8 (SD 10.4) in the usual care arm (adjusted between group difference −1.4, 95% confidence interval −2.6 to −0.2, P=0.03). This indicates greater cognitive impairment in the exercise group, although the average difference is small and clinical relevance uncertain. No differences were found in secondary outcomes or preplanned subgroup analyses by dementia type (Alzheimer’s disease or other), severity of cognitive impairment, sex, and mobility. Compliance with exercise was good. Over 65% of participants (214/329) attended more than three quarters of scheduled sessions. Six minute walking distance improved over six weeks (mean change 18.1 m, 95% confidence interval 11.6 m to 24.6 m).

Conclusion A moderate to high intensity aerobic and strength exercise training programme does not slow cognitive impairment in people with mild to moderate dementia. The exercise training programme improved physical fitness, but there were no noticeable improvements in other clinical outcomes.

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Neuro-computational Impact of Physical #Training Overload on Economic #Decision-Making

Highlights
• Training overload in endurance sport induces cognitive control fatigue

• Training-induced fatigue is associated with reduced prefrontal cortex activity

• Training-induced fatigue is associated with enhanced choice impulsivity

• Excessive physical training and intellectual work induce similar cognitive fatigue

At the neural level, training overload resulted in diminished activation of the lateral prefrontal cortex, a key region of the cognitive control system, during economic choice. Our results therefore provide causal evidence for a functional link between enduring physical exercise and exerting cognitive control.

Besides, the concept of cognitive control fatigue bridges the functional consequences of excessive physical training and intellectual work into a single neuro-computational mechanism, which might contribute to other clinical forms of burnout syndromes.

https://www.sciencedirect.com/science/article/pii/S0960982219311042

Effect of High-Intensity Strength #Training on #Knee Pain and Knee Joint Compressive Forces Among Adults With Knee #Osteoarthritis
https://2medical.news/2021/02/18/effect-of-high-intensity-strength-training-on-knee-pain-and-knee-joint-compressive-forces-among-adults-with-knee-osteoarthritis/

Thigh muscle weakness is associated with knee discomfort and osteoarthritis disease progression. Little is known about the efficacy of high-intensity strength training in patients with knee osteoarthritis or whether it may worsen knee symptoms. Objective To determine whether high-intensity strength training reduces knee pain and knee joint compressive forces more than low-intensity strength training and more than attention control in patients with knee osteoarthritis. Design, …

OR10-1 – Efficacy of High-Intensity Intermittent #Training for Improving Cardio-Metabolic Health in Women With #Polycystic Ovary Syndrome
https://2medical.news/2021/03/25/or10-1-efficacy-of-high-intensity-intermittent-training-for-improving-cardio-metabolic-health-in-women-with-polycystic-ovary-syndrome/

Polycystic ovary syndrome (PCOS) is a common and complex endocrinopathy with significant metabolic and reproductive manifestations, carrying a major health and economic burden. Consistent improvements in clinical outcomes have been reported as a result of exercise training, but shortfalls with exercise prescription are evident. Research suggests that high-intensity intermittent training (HIIT) is feasible, well tolerated and enjoyable for people with or at risk of chronic …

Long-Term Improvement in Hippocampal-Dependent #Learning Ability in Healthy, Aged Individuals Following High Intensity Interval #Training

https://2medical.news/2024/08/14/long-term-improvement-in-hippocampal-dependent-learning-ability-in-healthy-aged-individuals-following-high-intensity-interval-training/