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Aldo Lorenzetti M.D, Internal Medicine & Hepatology, Milano - SIMEDET Delegate
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#Tea consumption reduces the incidence of #neurocognitive disorders: Findings from the Singapore longitudinal aging study
https://link.springer.com/article/10.1007/s12603-016-0687-0

Tea intake was associated with lower risk of incident NCD, independent of other risk factors. Reduced NCD risk was observed for both green tea (OR=0.43) and black/oolong tea (OR=0.53) and appeared to be influenced by the changing of tea consumption habit at follow-up. Using consistent nontea consumers as the reference, only consistent tea consumers had reduced risk of NCD (OR=0.39). Stratified analyses indicated that tea consumption was associated with reduced risk of NCD among females (OR=0.32) and APOE e4 carriers (OR=0.14) but not males and non APOE e4 carriers.

Conclusion

Regular tea consumption was associated with lower risk of neurocognitive disorders among Chinese elderly. Gender and genetic factors could possibly modulate this association.
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#Neurocognitive development in perinatally #HIV-infected adolescents on long-term treatment compared to healthy matched controls: a longitudinal study

https://academic.oup.com/cid/advance-article/doi/10.1093/cid/ciz386/5492020

Cross-sectional analysis of the NOVICE cohort showed significant cognitive impairment in combination antiretroviral therapy (cART)-treated perinatally HIV-infected adolescents (PHIV+) compared to age-, sex-, ethnicity- and socioeconomic status (SES)-matched HIV-negative controls (HIV-).

Processing speed, working memory, learning ability and visual-motor function trajectories were not statistically different between groups. Univariately, those who had started cART at older age deviated more in executive functioning (-0.13 z-score, 95%CI -0.24 to -0.02, p=0.043). The prevalence of cognitive impairment by MNC was similar in both groups at both time-points.

Conclusions
cART-treated PHIV+ adolescents appear to have similar global cognitive development compared to healthy peers. Executive functioning trajectory appears to deviate, potentially explained by earlier brain damage.
The efficacy of #exergaming in people with major #neurocognitive disorder residing in long-term care facilities: a pilot randomized controlled trial
https://2medical.news/2021/04/19/the-efficacy-of-exergaming-in-people-with-major-neurocognitive-disorder-residing-in-long-term-care-facilities-a-pilot-randomized-controlled-trial/

It is currently unknown whether exergaming is efficacious in people with major neurocognitive disorder (MNCD) residing in long-term care facilities. This pilot randomized controlled trial (RCT) explored the efficacy of a stepping exergame program on gait speed, balance, mobility, reaction time, cognitive and neuropsychiatric outcomes, quality of life, and daily life functioning in people with MNCD residing in long-term care facilities. Methods Participants were randomly …