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Association of Low-Carbohydrate and Low-Fat #Diets With #Mortality Among US Adults
..Overall low-carbohydrate-diet and low-fat-diet scores were not associated with total mortality. The multivariable-adjusted hazard ratios for total mortality per 20-percentile increase in dietary scores were 1.07 (95% CI, 1.02-1.11; P = .01 for trend) for unhealthy low-carbohydrate-diet score, 0.91 (95% CI, 0.87-0.95; P < .001 for trend) for healthy low-carbohydrate-diet score, 1.06 (95% CI, 1.01-1.12; P = .04 for trend) for unhealthy low-fat-diet score, and 0.89 (95% CI, 0.85-0.93; P < .001 for trend) for healthy low-fat-diet score. The associations remained similar in the stratification and sensitivity analyses.
Conclusions and Relevance In this study, overall low-carbohydrate-diet and low-fat-diet scores were not associated with total mortality. Unhealthy low-carbohydrate-diet and low-fat-diet scores were associated with higher total mortality, whereas healthy low-carbohydrate-diet and low-fat-diet scores were associated with lower total mortality. These findings suggest that the associations of low-carbohydrate and low-fat diets with mortality may depend on the quality and food sources of macronutrients.
https://bit.ly/2vsDhWZ
Association of Low-Carbohydrate and Low-Fat #Diets With #Mortality Among US Adults
..Overall low-carbohydrate-diet and low-fat-diet scores were not associated with total mortality. The multivariable-adjusted hazard ratios for total mortality per 20-percentile increase in dietary scores were 1.07 (95% CI, 1.02-1.11; P = .01 for trend) for unhealthy low-carbohydrate-diet score, 0.91 (95% CI, 0.87-0.95; P < .001 for trend) for healthy low-carbohydrate-diet score, 1.06 (95% CI, 1.01-1.12; P = .04 for trend) for unhealthy low-fat-diet score, and 0.89 (95% CI, 0.85-0.93; P < .001 for trend) for healthy low-fat-diet score. The associations remained similar in the stratification and sensitivity analyses.
Conclusions and Relevance In this study, overall low-carbohydrate-diet and low-fat-diet scores were not associated with total mortality. Unhealthy low-carbohydrate-diet and low-fat-diet scores were associated with higher total mortality, whereas healthy low-carbohydrate-diet and low-fat-diet scores were associated with lower total mortality. These findings suggest that the associations of low-carbohydrate and low-fat diets with mortality may depend on the quality and food sources of macronutrients.
https://bit.ly/2vsDhWZ
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#Education, Race/Ethnicity, and Causes of Premature #Mortality Among Middle-Aged Adults in 4 US Urban Communities: Results From CARDIA, 1985–2017
..Our primary outcome was years of potential life lost (YPLL).
Results. The age-adjusted mortality rate per 1000 persons was 45.17 among Black men, 25.20 among White men, 17.63 among Black women, and 10.10 among White women. Homicide and AIDS were associated with the most YPLL, but cancer and cardiovascular disease were the most common causes of death. In multivariable models, each level of education achieved was associated with 1.37 fewer YPLL (P = .007); race/ethnicity was not independently associated with YPLL.
Conclusions. Lower education level was an independent predictor of greater YPLL
https://bit.ly/2HQaTkt
#Education, Race/Ethnicity, and Causes of Premature #Mortality Among Middle-Aged Adults in 4 US Urban Communities: Results From CARDIA, 1985–2017
..Our primary outcome was years of potential life lost (YPLL).
Results. The age-adjusted mortality rate per 1000 persons was 45.17 among Black men, 25.20 among White men, 17.63 among Black women, and 10.10 among White women. Homicide and AIDS were associated with the most YPLL, but cancer and cardiovascular disease were the most common causes of death. In multivariable models, each level of education achieved was associated with 1.37 fewer YPLL (P = .007); race/ethnicity was not independently associated with YPLL.
Conclusions. Lower education level was an independent predictor of greater YPLL
https://bit.ly/2HQaTkt
American Public Health Association (APHA) publications
The American Journal of Public Health (AJPH) from the American Public Health Association (APHA) publications
Estimates of the Association of #Dementia With US #Mortality Levels Using Linked Survey and Mortality Records
https://2medical.news/2020/09/04/estimates-of-the-association-of-dementia-with-us-mortality-levels-using-linked-survey-and-mortality-records/
Vital statistics are the primary source of data used to understand the mortality burden of dementia in the US, despite evidence that dementia is underreported on death certificates. Alternative estimates, drawing on population-based samples, are needed ..Of the 7342 total sample, 4348 participants (60.3%) were women. At baseline, 4533 individuals (64.0%) were between ages 70 and 79 years, 2393 individuals (31.0%) were between 80 and …
https://2medical.news/2020/09/04/estimates-of-the-association-of-dementia-with-us-mortality-levels-using-linked-survey-and-mortality-records/
Vital statistics are the primary source of data used to understand the mortality burden of dementia in the US, despite evidence that dementia is underreported on death certificates. Alternative estimates, drawing on population-based samples, are needed ..Of the 7342 total sample, 4348 participants (60.3%) were women. At baseline, 4533 individuals (64.0%) were between ages 70 and 79 years, 2393 individuals (31.0%) were between 80 and …
Estimates of the Association of #Dementia With US #Mortality Levels Using Linked Survey and Mortality Records
https://2medical.news/2020/09/09/estimates-of-the-association-of-dementia-with-us-mortality-levels-using-linked-survey-and-mortality-records-2/
..Of the 7342 total sample, 4348 participants (60.3%) were women. At baseline, 4533 individuals (64.0%) were between ages 70 and 79 years, 2393 individuals (31.0%) were between 80 and 89 years, and 416 individuals (5.0%) were between 90 and 99 years; percentages were weighted. The percentage of deaths attributable to dementia was 13.6% (95% CI, 12.2%-15.0%) between 2000 and 2009. The mortality burden of dementia …
https://2medical.news/2020/09/09/estimates-of-the-association-of-dementia-with-us-mortality-levels-using-linked-survey-and-mortality-records-2/
..Of the 7342 total sample, 4348 participants (60.3%) were women. At baseline, 4533 individuals (64.0%) were between ages 70 and 79 years, 2393 individuals (31.0%) were between 80 and 89 years, and 416 individuals (5.0%) were between 90 and 99 years; percentages were weighted. The percentage of deaths attributable to dementia was 13.6% (95% CI, 12.2%-15.0%) between 2000 and 2009. The mortality burden of dementia …
Low #carbohydrate diet and all cause and cause-specific #mortality
https://2medical.news/2020/09/29/low-carbohydrate-diet-and-all-cause-and-cause-specific-mortality/
Evidence is limited regarding the association between low-carbohydrate diet (LCD) score and mortality among Asians, a population that consumes a large amount of carbohydrates.. ..A U-shaped association was observed between LCD score and total mortality: the multivariable-adjusted hazard ratios (HRs) (95% CI) of total mortality for lowest through highest scores were 1.00, 0.95 (0.91, 1.01), 0.93 (0.88, 0.98), 0.93 (0.88, 0.98), and 1.01 (0.95, 1.07) …
https://2medical.news/2020/09/29/low-carbohydrate-diet-and-all-cause-and-cause-specific-mortality/
Evidence is limited regarding the association between low-carbohydrate diet (LCD) score and mortality among Asians, a population that consumes a large amount of carbohydrates.. ..A U-shaped association was observed between LCD score and total mortality: the multivariable-adjusted hazard ratios (HRs) (95% CI) of total mortality for lowest through highest scores were 1.00, 0.95 (0.91, 1.01), 0.93 (0.88, 0.98), 0.93 (0.88, 0.98), and 1.01 (0.95, 1.07) …
#BMI and All‐Cause #Mortality in a Population‐Based Cohort in Rural South Africa
https://2medical.news/2020/10/26/bmi-and-all%E2%80%90cause-mortality-in-a-population%E2%80%90based-cohort-in-rural-south-africa/
..The cohort consisted of 9,728 individuals. In adjusted models, those with BMI of 25.0 to 29.9 kg/m2 or 30.0 to 34.9 kg/m2 had a lower hazard of death (adjusted hazard ratio: 0.80; 95% CI: 0.69‐0.92 and adjusted hazard ratio: 0.75; 95% CI: 0.60‐0.93, respectively) compared with those with BMI of 18.5 to 24.9 kg/m2. Conclusions Individuals in South Africa who meet clinically defined criteria for …
https://2medical.news/2020/10/26/bmi-and-all%E2%80%90cause-mortality-in-a-population%E2%80%90based-cohort-in-rural-south-africa/
..The cohort consisted of 9,728 individuals. In adjusted models, those with BMI of 25.0 to 29.9 kg/m2 or 30.0 to 34.9 kg/m2 had a lower hazard of death (adjusted hazard ratio: 0.80; 95% CI: 0.69‐0.92 and adjusted hazard ratio: 0.75; 95% CI: 0.60‐0.93, respectively) compared with those with BMI of 18.5 to 24.9 kg/m2. Conclusions Individuals in South Africa who meet clinically defined criteria for …
Association of Medical #Stimulants With #Mortality in the US From 2010 to 2017
https://2medical.news/2021/02/04/association-of-medical-stimulants-with-mortality-in-the-us-from-2010-to-2017/
The role of nonopioids in the drug overdose epidemic in the US is frequently overshadowed. From 2015 to 2016, mortality rates involving cocaine and psychostimulants were smaller than opioids, but were rising faster than opioids.1 We examined individual substances listed on death certificates to better understand stimulant-associated mortality and assess rates over time. https://bit.ly/3oEgFbP
https://2medical.news/2021/02/04/association-of-medical-stimulants-with-mortality-in-the-us-from-2010-to-2017/
The role of nonopioids in the drug overdose epidemic in the US is frequently overshadowed. From 2015 to 2016, mortality rates involving cocaine and psychostimulants were smaller than opioids, but were rising faster than opioids.1 We examined individual substances listed on death certificates to better understand stimulant-associated mortality and assess rates over time. https://bit.ly/3oEgFbP
#Personality pathways to mortality: Interleukin-6 links conscientiousness to #mortality risk
https://2medical.news/2021/02/26/personality-pathways-to-mortality-interleukin-6-links-conscientiousness-to-mortality-risk/
Personality is associated consistently with mortality hazards, but the physiological pathways are not yet clear. Immune system dysregulation may be one such pathway due to its role in age-related morbidity and mortality. In this preregistered study, we tested whether interleukin-6 (IL-6) and C-reactive protein (CRP) mediated the associations between personality traits and mortality hazards. The sample included 957 participants (M ± SD = 58.65 ± …
https://2medical.news/2021/02/26/personality-pathways-to-mortality-interleukin-6-links-conscientiousness-to-mortality-risk/
Personality is associated consistently with mortality hazards, but the physiological pathways are not yet clear. Immune system dysregulation may be one such pathway due to its role in age-related morbidity and mortality. In this preregistered study, we tested whether interleukin-6 (IL-6) and C-reactive protein (CRP) mediated the associations between personality traits and mortality hazards. The sample included 957 participants (M ± SD = 58.65 ± …
Association of Major Dietary #Protein Sources With All‐Cause and Cause‐Specific #Mortality: Prospective Cohort Study
https://2medical.news/2021/03/01/association-of-major-dietary-protein-sources-with-all%E2%80%90cause-and-cause%E2%80%90specific-mortality-prospective-cohort-study/
Dietary recommendations regarding protein intake have been focused on the amount of protein. However, such recommendations without considering specific protein sources may be simplistic and insufficient. Methods and Results We included 102 521 postmenopausal women enrolled in the Women’s Health Initiative between 1993 and 1998, and followed them through February 2017. During 1 876 205 person‐years of follow‐up, 25 976 deaths occurred. Comparing the highest …
https://2medical.news/2021/03/01/association-of-major-dietary-protein-sources-with-all%E2%80%90cause-and-cause%E2%80%90specific-mortality-prospective-cohort-study/
Dietary recommendations regarding protein intake have been focused on the amount of protein. However, such recommendations without considering specific protein sources may be simplistic and insufficient. Methods and Results We included 102 521 postmenopausal women enrolled in the Women’s Health Initiative between 1993 and 1998, and followed them through February 2017. During 1 876 205 person‐years of follow‐up, 25 976 deaths occurred. Comparing the highest …
Association of spontaneous #abortion with all cause and cause specific premature #mortality: prospective cohort study
https://2medical.news/2021/03/26/association-of-spontaneous-abortion-with-all-cause-and-cause-specific-premature-mortality-prospective-cohort-study/
To investigate the association of spontaneous abortion with the risk of all cause and cause specific premature mortality (death before the age of 70). Design Prospective cohort study. Setting The Nurses’ Health Study II (1993-2017), United States. Participants 101 681 ever gravid female nurses participating in the Nurses’ Health Study II. Main outcomes measures Lifetime occurrence of spontaneous abortion in pregnancies lasting less than 6 months, …
https://2medical.news/2021/03/26/association-of-spontaneous-abortion-with-all-cause-and-cause-specific-premature-mortality-prospective-cohort-study/
To investigate the association of spontaneous abortion with the risk of all cause and cause specific premature mortality (death before the age of 70). Design Prospective cohort study. Setting The Nurses’ Health Study II (1993-2017), United States. Participants 101 681 ever gravid female nurses participating in the Nurses’ Health Study II. Main outcomes measures Lifetime occurrence of spontaneous abortion in pregnancies lasting less than 6 months, …