Longevity InTime: Autonomous AI Institute. Anti-Aging Digital Health Immortality Transhumanist AI Channel pinned «We launch a contest for the main image of the Longevity Coin (LONG) Mini App Game in Telegram and a potential character of the Coin / Game. Send your works to our: https://t.me/LongevityCoinGroup The first 3 winners will get 10,000$ worth in Longevity Coin…»
Leading aging researcher Joao Pedro de Magalhães answers the question: what are the main achievements in aging research in the 21st century?
- Rapamycin increases the lifespan of animals.
- Yamanaka factors.
- Epigenetic clock.
https://x.com/jpsenescence/status/1835028935970898400
Unfortunately, these are extremely insignificant results for a quarter of a century. The situation cannot but upset, and of course we are upset.
On the other hand, overoptimists are raging at Longevity. Their main trump card is that it is not long until AGI, and therefore immortality. This cannot but please, and of course we are happy.
The atmosphere in the field is a schizoid dichotomy: at the same time it seems that everything is lost, and at the same time that everything will be resolved soon.
So what should we do? There is a simple solution from Brian Johnson: let's go to bed on time. That is, a healthy lifestyle and stem cells, and then the superintelligence of the future will come and cure everyone.
There is also the Longevity Biotech Startup Universe.
In the third Universe they say: “Well, for God’s sake, what startups, let’s develop the theory of aging or collect more data.”
There are the fourth, fifth, sixth universes, which are related to politics, tools, roadmaps, methods, and so on.
And what about us? What does the voice of transhumanist reason say? “Everything is complicated,” it says. But it is precisely this complexity that we must rush into.
The gods of transhumanism from Berkeley believe that the most important thing is an executable philosophy: to build ethical rules into AGI at the code level so that it does not destroy us. They got an article, but did not have enough funding for global implementation.
https://arxiv.org/abs/1609.03543
An executable philosophy is an incredibly difficult task, and maybe try to solve iteratively? Why not start using AI for good deeds now?
https://boriskriger.com/dobro/
There is another factor: increasing the armament of the Longevity community with AI tools to increase the influence of the community. Remember how with the advent of MidJourney we gave everyone access and helped them use it at an early stage?
Well, this work needs to continue. In this way, we will create many intelligent agents acting in favor of immortality, combining artificial intelligence with natural intelligence.
- Rapamycin increases the lifespan of animals.
- Yamanaka factors.
- Epigenetic clock.
https://x.com/jpsenescence/status/1835028935970898400
Unfortunately, these are extremely insignificant results for a quarter of a century. The situation cannot but upset, and of course we are upset.
On the other hand, overoptimists are raging at Longevity. Their main trump card is that it is not long until AGI, and therefore immortality. This cannot but please, and of course we are happy.
The atmosphere in the field is a schizoid dichotomy: at the same time it seems that everything is lost, and at the same time that everything will be resolved soon.
So what should we do? There is a simple solution from Brian Johnson: let's go to bed on time. That is, a healthy lifestyle and stem cells, and then the superintelligence of the future will come and cure everyone.
There is also the Longevity Biotech Startup Universe.
In the third Universe they say: “Well, for God’s sake, what startups, let’s develop the theory of aging or collect more data.”
There are the fourth, fifth, sixth universes, which are related to politics, tools, roadmaps, methods, and so on.
And what about us? What does the voice of transhumanist reason say? “Everything is complicated,” it says. But it is precisely this complexity that we must rush into.
The gods of transhumanism from Berkeley believe that the most important thing is an executable philosophy: to build ethical rules into AGI at the code level so that it does not destroy us. They got an article, but did not have enough funding for global implementation.
https://arxiv.org/abs/1609.03543
An executable philosophy is an incredibly difficult task, and maybe try to solve iteratively? Why not start using AI for good deeds now?
https://boriskriger.com/dobro/
There is another factor: increasing the armament of the Longevity community with AI tools to increase the influence of the community. Remember how with the advent of MidJourney we gave everyone access and helped them use it at an early stage?
Well, this work needs to continue. In this way, we will create many intelligent agents acting in favor of immortality, combining artificial intelligence with natural intelligence.
X (formerly Twitter)
João Pedro de Magalhães (@jpsenescence) on X
What are the main breakthroughs in aging research in the 21st century?
I can think of three:
- Rapamycin extending lifespan in animals
- Yamanaka factors
- Epigenetic clocks
Anything else?
I can think of three:
- Rapamycin extending lifespan in animals
- Yamanaka factors
- Epigenetic clocks
Anything else?
"Can AI Help You Live Longer?"
Imagine if a machine could predict when you might get sick and suggest ways to prevent it. AI is already being used to analyze vast amounts of health data to identify patterns we can't see. In fact, AI systems have been shown to predict diseases like diabetes or heart conditions *before* they happen.
One recent study by MIT used AI to predict the onset of breast cancer with 94% accuracy! This kind of innovation might help us all live healthier and longer lives by catching diseases early.
- Curious? Read more about AI and health predictions (https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7679572/).
Imagine if a machine could predict when you might get sick and suggest ways to prevent it. AI is already being used to analyze vast amounts of health data to identify patterns we can't see. In fact, AI systems have been shown to predict diseases like diabetes or heart conditions *before* they happen.
One recent study by MIT used AI to predict the onset of breast cancer with 94% accuracy! This kind of innovation might help us all live healthier and longer lives by catching diseases early.
- Curious? Read more about AI and health predictions (https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7679572/).
PubMed Central (PMC)
Validación de dos sistemas de automedida de presión arterial, modelos OMRON HEM-705 CP y OMRON M1 (HEM 422C2-E)
Validar dos monitores comercializados para la automedida de la presión arterial (AMPA), uno automático (OMRON HEM-705 CP) y otro semiautomático (OMRON M1).Estudio descriptivo de validación de pruebas diagnósticas.Atención ...
"5 Foods to Boost Your Longevity 🥦🍓"
Want to add years to your life? What you eat plays a crucial role! Scientists have found that certain foods are packed with nutrients that promote longevity. Here are five superfoods to add to your diet:
1. Leafy Greens (Spinach, Kale) – Rich in vitamins and antioxidants.
2. Berries (Blueberries, Strawberries) – Packed with antioxidants to protect your cells.
3. Nuts (Almonds, Walnuts) – Full of healthy fats and protein for heart health.
4. Olive Oil – Known for its anti-inflammatory properties.
5. Fatty Fish (Salmon, Sardines) – Omega-3 fatty acids help reduce inflammation.
Discover more about the science of nutrition and longevity [here](https://www.health.harvard.edu/staying-healthy/eating-to-break-100).
Want to add years to your life? What you eat plays a crucial role! Scientists have found that certain foods are packed with nutrients that promote longevity. Here are five superfoods to add to your diet:
1. Leafy Greens (Spinach, Kale) – Rich in vitamins and antioxidants.
2. Berries (Blueberries, Strawberries) – Packed with antioxidants to protect your cells.
3. Nuts (Almonds, Walnuts) – Full of healthy fats and protein for heart health.
4. Olive Oil – Known for its anti-inflammatory properties.
5. Fatty Fish (Salmon, Sardines) – Omega-3 fatty acids help reduce inflammation.
Discover more about the science of nutrition and longevity [here](https://www.health.harvard.edu/staying-healthy/eating-to-break-100).
"Is Aging a Disease We Can Cure? 🧬"
Could you imagine a world where aging is treated as a disease? Scientists like Dr. David Sinclair believe it's possible. Aging causes our cells to stop repairing themselves, leading to diseases like cancer and heart disease. But what if we could reverse this process? New research into treatments like NAD+ boosters and Senolytics (drugs that kill aging cells) shows promising results.
The idea of curing aging isn’t science fiction anymore—it’s closer than we think. Learn more about this groundbreaking research [here](https://www.sciencedirect.com/science/article/pii/S2211124719309082).
Could you imagine a world where aging is treated as a disease? Scientists like Dr. David Sinclair believe it's possible. Aging causes our cells to stop repairing themselves, leading to diseases like cancer and heart disease. But what if we could reverse this process? New research into treatments like NAD+ boosters and Senolytics (drugs that kill aging cells) shows promising results.
The idea of curing aging isn’t science fiction anymore—it’s closer than we think. Learn more about this groundbreaking research [here](https://www.sciencedirect.com/science/article/pii/S2211124719309082).
👍1
More drafts of screens of the Longevity Coin mini app game in Telegram
How Fasting Can Extend Your Life 🕰️
Did you know intermittent fasting may hold the secret to a longer life? Studies show that fasting activates your body's repair processes, helping to clean out damaged cells and even improve brain function. In one study, fasting mice lived up to 30% longer than their well-fed counterparts. Want to try it? Even fasting for just 12-16 hours a day can give your body time to repair and reset.
Read more about the science behind fasting and longevity [here](https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5783752/).
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AI Detects Alzheimer’s 6 Years Before Symptoms Show 🧠
Early detection of Alzheimer's could be a game-changer, and AI is making it possible. New research shows that AI can detect early signs of Alzheimer’s disease with up to 90% accuracy, years before any symptoms show. This could lead to earlier treatments, potentially slowing the disease's progression. It’s one more way that AI is revolutionizing healthcare and giving us tools to live healthier, longer lives.
Learn more about this incredible discovery [here](https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7692087/).
---
How Sleep Affects Longevity 💤
Want to live longer? Get more sleep! Research shows that people who sleep 7-8 hours per night have a 12% lower risk of dying from any cause compared to those who sleep less. Sleep helps repair your body, boosts immune function, and even improves brain health. If you’re missing out on quality sleep, it might be time to prioritize rest for the sake of your longevity.
Find out more about the importance of sleep [here](https://pubmed.ncbi.nlm.nih.gov/33188316/).
Did you know intermittent fasting may hold the secret to a longer life? Studies show that fasting activates your body's repair processes, helping to clean out damaged cells and even improve brain function. In one study, fasting mice lived up to 30% longer than their well-fed counterparts. Want to try it? Even fasting for just 12-16 hours a day can give your body time to repair and reset.
Read more about the science behind fasting and longevity [here](https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5783752/).
---
AI Detects Alzheimer’s 6 Years Before Symptoms Show 🧠
Early detection of Alzheimer's could be a game-changer, and AI is making it possible. New research shows that AI can detect early signs of Alzheimer’s disease with up to 90% accuracy, years before any symptoms show. This could lead to earlier treatments, potentially slowing the disease's progression. It’s one more way that AI is revolutionizing healthcare and giving us tools to live healthier, longer lives.
Learn more about this incredible discovery [here](https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7692087/).
---
How Sleep Affects Longevity 💤
Want to live longer? Get more sleep! Research shows that people who sleep 7-8 hours per night have a 12% lower risk of dying from any cause compared to those who sleep less. Sleep helps repair your body, boosts immune function, and even improves brain health. If you’re missing out on quality sleep, it might be time to prioritize rest for the sake of your longevity.
Find out more about the importance of sleep [here](https://pubmed.ncbi.nlm.nih.gov/33188316/).
PubMed Central (PMC)
Flipping the Metabolic Switch: Understanding and Applying Health Benefits of Fasting
Intermittent fasting (IF) is a term used to describe a variety of eating patterns in which no or few calories are consumed for time periods that can range from 12 hours to several days, on a recurring basis. Here we focus on the physiological ...
How Plant-Based Diets Promote Longevity 🌱
Research shows that plant-based diets can significantly extend life expectancy. By focusing on vegetables, fruits, legumes, and whole grains, you're feeding your body powerful nutrients that lower the risk of chronic diseases like heart disease and cancer. A large study published in *The Lancet* found that eating more plant-based foods could add up to 10 years to your life!
Curious about switching to more plants in your diet? Discover the science behind it [here](https://www.thelancet.com/journals/lancet/article/PIIS0140-6736(19)30041-8/fulltext).
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Can Metformin Slow Aging? 🧬
Metformin, a common drug for type 2 diabetes, has been found to have anti-aging potential. Studies suggest that metformin can mimic the effects of calorie restriction, which is known to extend lifespan in animals. The TAME (Targeting Aging with Metformin) trial is currently underway to test whether this medication can slow aging in humans by reducing the risk of age-related diseases.
Learn more about the exciting research on metformin and aging [here](https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6913787/).
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Cold Exposure for a Longer Life? ❄️
Did you know that brief exposure to cold temperatures could help you live longer? Cold therapy, or cold exposure, has been linked to increased longevity by activating brown fat, improving metabolism, and reducing inflammation. In fact, studies show that cold exposure can stimulate cellular repair and boost immune function.
Want to try it yourself? Learn more about cold therapy and its benefits for longevity [here](https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6473775/).
Research shows that plant-based diets can significantly extend life expectancy. By focusing on vegetables, fruits, legumes, and whole grains, you're feeding your body powerful nutrients that lower the risk of chronic diseases like heart disease and cancer. A large study published in *The Lancet* found that eating more plant-based foods could add up to 10 years to your life!
Curious about switching to more plants in your diet? Discover the science behind it [here](https://www.thelancet.com/journals/lancet/article/PIIS0140-6736(19)30041-8/fulltext).
---
Can Metformin Slow Aging? 🧬
Metformin, a common drug for type 2 diabetes, has been found to have anti-aging potential. Studies suggest that metformin can mimic the effects of calorie restriction, which is known to extend lifespan in animals. The TAME (Targeting Aging with Metformin) trial is currently underway to test whether this medication can slow aging in humans by reducing the risk of age-related diseases.
Learn more about the exciting research on metformin and aging [here](https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6913787/).
---
Cold Exposure for a Longer Life? ❄️
Did you know that brief exposure to cold temperatures could help you live longer? Cold therapy, or cold exposure, has been linked to increased longevity by activating brown fat, improving metabolism, and reducing inflammation. In fact, studies show that cold exposure can stimulate cellular repair and boost immune function.
Want to try it yourself? Learn more about cold therapy and its benefits for longevity [here](https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6473775/).
The Lancet
Health effects of dietary risks in 195 countries, 1990–2017: a systematic analysis for the Global Burden of Disease Study 2017
This study provides a comprehensive picture of the potential impact of suboptimal
diet on NCD mortality and morbidity, highlighting the need for improving diet across
nations. Our findings will inform implementation of evidence-based dietary interventions…
diet on NCD mortality and morbidity, highlighting the need for improving diet across
nations. Our findings will inform implementation of evidence-based dietary interventions…
Blue Zones: Secrets to Living Over 100 🌍
Blue Zones are regions around the world where people consistently live to be 100 years old or more. What’s their secret? Researchers found common lifestyle factors: plant-based diets, regular physical activity, strong social connections, and a sense of purpose in life. These areas include Okinawa in Japan, Sardinia in Italy, and Nicoya in Costa Rica.
Explore the lifestyle habits of Blue Zones and how you can apply them to your life for longevity [here](https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6125071/).
---
AI-Powered Blood Tests: Predicting Health Issues Early 🔬
New AI technologies are making blood tests more powerful than ever. AI can now analyze complex biomarkers to detect early signs of diseases like cancer, diabetes, and heart conditions even before symptoms appear. These tests provide a new frontier in preventative healthcare, potentially adding years to your life by catching problems early.
Learn more about how AI is transforming blood tests for early disease detection [here](https://www.nature.com/articles/s41746-019-0115-7).
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Can Mindfulness Meditation Slow Aging? 🧘♂️
Mindfulness meditation may do more than reduce stress—it could help slow down aging! Studies show that meditation can lengthen telomeres, the protective caps on our chromosomes that naturally shorten as we age. Longer telomeres are associated with longer lifespans and better overall health. Regular mindfulness practice has been linked to improved immune function, lower inflammation, and slower aging.
Interested in how meditation could extend your life? Find out more [here](https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5935642/).
Blue Zones are regions around the world where people consistently live to be 100 years old or more. What’s their secret? Researchers found common lifestyle factors: plant-based diets, regular physical activity, strong social connections, and a sense of purpose in life. These areas include Okinawa in Japan, Sardinia in Italy, and Nicoya in Costa Rica.
Explore the lifestyle habits of Blue Zones and how you can apply them to your life for longevity [here](https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6125071/).
---
AI-Powered Blood Tests: Predicting Health Issues Early 🔬
New AI technologies are making blood tests more powerful than ever. AI can now analyze complex biomarkers to detect early signs of diseases like cancer, diabetes, and heart conditions even before symptoms appear. These tests provide a new frontier in preventative healthcare, potentially adding years to your life by catching problems early.
Learn more about how AI is transforming blood tests for early disease detection [here](https://www.nature.com/articles/s41746-019-0115-7).
---
Can Mindfulness Meditation Slow Aging? 🧘♂️
Mindfulness meditation may do more than reduce stress—it could help slow down aging! Studies show that meditation can lengthen telomeres, the protective caps on our chromosomes that naturally shorten as we age. Longer telomeres are associated with longer lifespans and better overall health. Regular mindfulness practice has been linked to improved immune function, lower inflammation, and slower aging.
Interested in how meditation could extend your life? Find out more [here](https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5935642/).
PubMed Central (PMC)
Blue Zones
What began as a National Geographic expedition, lead by Dan Buettner, to uncover the secrets of longevity, evolved into the discovery of the 5 places around the world where people consistently live over 100 years old, dubbed the Blue Zones. Dan and his ...