The journey between identifying a potential therapeutic compound and Food and Drug Administration approval of a new drug can take well over a decade and cost upward of a billion dollars. A research team ...

Abstract. It is known that biological relatives of long-lived individuals demonstrate lower mortality and longer life span compared to relatives of shorter-live

Aging | doi:10.18632/aging.204391. Kento Takaya, Tatsuyuki Ishii, Toru Asou, Kazuo Kishi

A small human trial has tested CRISPR gene editing technology in the treatment of solid cancer tumors, including breast, colon, and lung cancer, with promising results.

In a study recently published in Biochemistry and Biophysics Reports, researchers have shown that growing natural killer (NK) cells and re-introducing them back into the human bloodstream reduces senescence markers in a wide variety of immune cells. Peripheral…

Nature Aging - The authors found that, across tissues and in multiple datasets, aging is accompanied by a length-associated transcriptome imbalance. In most cases, a decrease in the relative...

Researchers assess how the COVID-19 pandemic affected the neurological development of young adults.

The National Lab and Department of Energy announced a nuclear reaction that generated more energy than was required to power it -- a first for humankind.

Scripps Research and MIT scientists find that a modified immune protein harming brain connections is much more common in the brains of women with Alzheimer’s, compared to men.

Partial somatic cell reprogramming has been touted as a promising rejuvenation strategy. However, its association with mechanisms of aging and longevity at the molecular level remains unclear. We identified a robust transcriptomic signature of reprogramming…

The U.S. Food and Drug Administration on Friday approved Swiss drugmaker Ferring Pharmaceuticals' first gene therapy for treating adult patients with a type of bladder cancer.

Three approaches with a reputation for slowing aging processes have proven largely ineffective. For their study, researchers developed a new method to measure aging, which accounts for the complexity of aging in organisms.

Signal Transduction and Targeted Therapy - Aging and aging-related diseases: from molecular mechanisms to interventions and treatments

Researchers identified 20 drug candidates that reduce C4 immune protein secretion from astrocytes. The discovery could pave the way to treating schizophrenia and other disorders associated with C4 dysregulation in astrocytes.

This week, a multinational team of researchers announced they developed a new blood test that can reliably detect proteins specific to Alzheimer’s disease..

EBT-101 is novel gene-editing therapy that uses “molecular scissors” to cut HIV out of cells.