Karyorrhexis

🔸Slide of: Injured cell with affected nucleus, in 2nd phase
of nuclear damage (with Electron microscope)

🔶- Diagnosis:
Irreversible cell injury

🔸- Characteristic features:
Fragmentation of nucleus and the condensed chromatin

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🔸- Slide of: Injured cell, with affected Mitochondria
(with Electrone microscope)

🔸- Diagnosis :
Irreversible cell injury

🔸- Characteristic features :
Swollen Mitochondria , with Dark and large dense
bodies inside it .
🔸B - Changes in nucleus in irreversible cell injury ( lead to
cell necrosis ) by three Phases :
• Pyknosis
• Karyorrhexis
• Karyolysis ... As follow 
__

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Pyknosis

🔸Slide of: Injured cell with affected nucleus, in 1st phase
of nuclear damage (with electron microscope)

🔸- Diagnosis:
Irreversible cell injury

🔸- Characteristic features:
Condensed chromatin inside the nucleus "Pyknosis

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Karyolysis

🔸Slide of: Injured cell with affected nucleus , in 3rd phase of
nuclear damage (with electron microscope)

🔸-Diagnosis :
Irreversible cell injury

🔸-Characteristic features :
Dissolution of chromatin "Karyolysis" , there is fluid in the
site of nucleus give (Soup appearance).
____

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Coagulative necrosis



🔸Gross picture of Kidney (by observation of cortex &
medulla)

🔸- Diagnosis:
Area of infarction in Kidney (Coagulative necrosis)

🔸- Characteristic features:
Pale wedge-shape area, Yellow in color, with preserved
outline and apex directed inward "which determine the
place of occluded Blood vessel" and base directed toward the outer surface..🌹🌹

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🔸- Slide: Kidney (Microscopic picture)
ميزناها من خالل وجود ال Glomerulus التي ال توجد اال في الكلية.
🔸- Diagnosis:
Coagulative necrosis in Kidney

🔸- Characteristic features:
Dead tubular cells, There s preservation of their outline
and Architecture, with no observed nucleus
أي تظهر حدود الخاليا ولكن تختفي تفاصيل الخاليا والنواة بداخله

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🔸Slide: Liver (Microscope picture)

🔸- Diagnosis:
Coagulative necrosis in Liver

🔸- Characteristic features:
Dead hepatocytes (Around central vein), With preserved
Architecture and No nucleus.

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Liquefactive necrosis


- 🔹Gross picture of Brain
• ( ميزناها من خالل وجود Grey & white matters التي ال توجد إال في
الدماغ ) .
-🔹 Diagnosis:
Area of infarction in Brain (Liquefactive necrosis)

🔹- Characteristic features:
Area with cavity fill with fluid.
That may be due to hemorrhage, thrombosis ...etc. .

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🔸Slide: Brain

🔸- Diagnosis:
Liquefactive necrosis in Brain

🔸- Characteristic features:
Cavity filled with fluid, leukocytes and necrotic cells.
_

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🔸Gross picture of Lung

🔸- Diagnosis:
Caseous necrosis in Lung (Mainly due to TB, in 95% of
cases)

🔸- Characteristic features:
Semisolid, dry material has feel of cheese (cheesy like metatarsal

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🔸Slide: Lung (Microscopic picture)

🔸- Diagnosis:
Caseous Necrosis (mainly associated with TB in lung)

🔸- Characteristic features:
Area characterized by Granulomas surround
(Granular, eosinophil "pink" , Structureless Tissue and
outline of cells are NOT preserved *).
*أي لا يمكن تمييز الخلايا واشكالها وحدودها لكن نميز ظهور ما يشبه
الحبيبات وهذا الفارق بينها وبين fibrinoid

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🔥Parasites life cycles 🔥

⬅️مخططات لدورة حياة الباراسايت
🔘Protozoa
🔘Nematodes
🔘cestodae
🔘Trematodes
لتسهيل الفهم بطريقة رائعة🤩✨

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#بارا_عملي

🔥🤩باراسايت USML1 🤩🔥

🔘 جداول تتضمن الاشياء المهمة والمفيدة لمادة الباراسايت سواء العملي او النظري✨✨

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🔘Para. Lab

🔷Slides in Nematodes 🔷
👇👇👇👇

🔘Ascaris lumbericoides👇

🔘Entrobius vermicularis👇

🔘Trichuris trichiura 👇