Management of Ectopic Pregnancy
Stability of the patient
2. Availability of resources
3. Patient’s desire for future fertility
Medical management is preferred for early ectopic pregnancy
• Surgery is reserved for:
• Hemodynamically unstable patients
• Uncertain diagnosis
• Failure of medical treatment
Stability of the patient
2. Availability of resources
3. Patient’s desire for future fertility
Medical management is preferred for early ectopic pregnancy
• Surgery is reserved for:
• Hemodynamically unstable patients
• Uncertain diagnosis
• Failure of medical treatment
Laparotomy:
• Preferred in hemodynamically unstable patients
• Allows rapid control of bleeding
• Laparoscopy:
• Superior to laparotomy
• Gold standard in hemodynamically stable patients
• Preferred in hemodynamically unstable patients
• Allows rapid control of bleeding
• Laparoscopy:
• Superior to laparotomy
• Gold standard in hemodynamically stable patients
Type of Tubal Surgery
Salpingectomy:
• Removal of the entire tube
• Indicated when:
• Significant tubal damage
• Patient previously sterilized and does not desire fertility
• High likelihood of retained products
Salpingotomy:
• Removal of ectopic pregnancy with suturing of the tube
• Salpingostomy:
• Removal of ectopic pregnancy leaving the tube open to heal secondarily
Salpingectomy:
• Removal of the entire tube
• Indicated when:
• Significant tubal damage
• Patient previously sterilized and does not desire fertility
• High likelihood of retained products
Salpingotomy:
• Removal of ectopic pregnancy with suturing of the tube
• Salpingostomy:
• Removal of ectopic pregnancy leaving the tube open to heal secondarily
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Medical management i
Methotrexate1mg/kg
Systemically
• Or locally (under laparoscopic or ultrasound guidance)
Hemodynamically stable patient
• Early ectopic pregnancy
• No active bleeding
• Small ectopic mass less then4cm
.No fetal cardiac activity
.able to return to follow up
Systemically
• Or locally (under laparoscopic or ultrasound guidance)
Hemodynamically stable patient
• Early ectopic pregnancy
• No active bleeding
• Small ectopic mass less then4cm
.No fetal cardiac activity
.able to return to follow up
Normal vaginal flora mainly lactobacilli; normal vaginal pH < 4.5 (lactic acid from glycogen under estrogen effect
Discharge increases in pregnancy, mid-cycle, with combined OCPs.
higher pH increases infection risk (prepubertal, postmenopausal, after systemic antibiotics, after total hysterectomy
Bacterial Vaginosis Fishy malodorous grey, non-irritant.
Loss of lactobacilli + overgrowth of anaerobes; common organisms: Gardnerella vaginalis, Bacteroides,
Loss of lactobacilli + overgrowth of anaerobes; common organisms: Gardnerella vaginalis, Bacteroides,
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Bacterial Vaginosis Fishy malodorous grey, non-irritant. Loss of lactobacilli + overgrowth of anaerobes; common organisms: Gardnerella vaginalis, Bacteroides,
Amsel criteria: discharge + clue cells + positive whiff test
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Bacterial Vaginosis Fishy malodorous grey, non-irritant. Loss of lactobacilli + overgrowth of anaerobes; common organisms: Gardnerella vaginalis, Bacteroides,
Complications: ↑PID, post-hysterectomy infections, 2nd-trimester miscarriage/preterm labor, chorioamnionitis, post-CS endometriti
Trichomonas vaginitis STI parasite
purulent discharge ،vulvar pruritus،strawberry cervix”
purulent discharge ،vulvar pruritus،strawberry cervix”
Vulvovaginal Candidiasis
: Very common; Candida albicans ~90%
RF: antibiotics, pregnancy, diabetes
Severe pruritus; discharge watery → thick;
cervix normal.
: Very common; Candida albicans ~90%
RF: antibiotics, pregnancy, diabetes
Severe pruritus; discharge watery → thick;
cervix normal.
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Vulvovaginal Candidiasis : Very common; Candida albicans ~90% RF: antibiotics, pregnancy, diabetes Severe pruritus; discharge watery → thick; cervix normal.
treatment): Topical azoles (clotrimazole/miconazole) or fluconazole)
Genital ulcers & warts
HSV
Usually HSV-2; primary painful ulcers, grouped vesicles. Confirm by culture or antibody assay. Treat: acyclovir 400 mg
HSV
Usually HSV-2; primary painful ulcers, grouped vesicles. Confirm by culture or antibody assay. Treat: acyclovir 400 mg
Primary syphilis
Painless, hard ulcer (chancre)
• Indurated margins
• Appears at site of infection
• Heals spontaneously in 3–6 weeks
Secondary syphilis
Maculopapular rash (including palms & soles)
• Generalized lymphadenopathy
• Fever, malaise, sore throat
Screening VDRL
• RPR
Confirmatory Treponemal tests
Treatment
Benzathine penicillin G
• 2.4 million units IM – single dose
Painless, hard ulcer (chancre)
• Indurated margins
• Appears at site of infection
• Heals spontaneously in 3–6 weeks
Secondary syphilis
Maculopapular rash (including palms & soles)
• Generalized lymphadenopathy
• Fever, malaise, sore throat
Screening VDRL
• RPR
Confirmatory Treponemal tests
Treatment
Benzathine penicillin G
• 2.4 million units IM – single dose
Endocervicitis
50% caused by Neisseria gonorrhoeae or Chlamydia trachomatis.
Dyspareunia
• Mucopurulent discharge
• On speculum: yellow/green purulent discharge from the cervix
• Cervical ectropion (friable, bleeds on contact)
50% caused by Neisseria gonorrhoeae or Chlamydia trachomatis.
Dyspareunia
• Mucopurulent discharge
• On speculum: yellow/green purulent discharge from the cervix
• Cervical ectropion (friable, bleeds on contact)
Dual therapy due to resistance.
• Ceftriaxone 250 mg IM single dose
PLUS
• Azithromycin 1 g single dose OR Doxycycline 100 mg BID 7 days
Partner must be treated.
• Ceftriaxone 250 mg IM single dose
PLUS
• Azithromycin 1 g single dose OR Doxycycline 100 mg BID 7 days
Partner must be treated.
Pelvic Inflammatory Disease
Clinical diagnosis of infection of endometrium, fallopian tubes, ovaries.
Severe cases may progress to peritonitis.
Clinical diagnosis of infection of endometrium, fallopian tubes, ovaries.
Severe cases may progress to peritonitis.
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Pelvic Inflammatory Disease Clinical diagnosis of infection of endometrium, fallopian tubes, ovaries. Severe cases may progress to peritonitis.
Ascending STIs, mainly gonorrhea & chlamydia