Streptococcus pyogenes also causes toxic shock syndrome (TSS), which has clinical findings similar to those of staphylococcal TSS. However, streptococcal TSS typically has a recognizable site of pyogenic inflammation and blood cultures are often positive, whereas staphylococcal TSS typically has neither a site of pyogenic inflammation nor positive blood cultures.

Patients suspected to have acute rheumatic fever (ARF) or post-strep glomerulonephritis (PSGN) must first be confirmed to have had a previous strep infection. This is done by measuring ASO & anti-DNAase B titers. The latter is better since it remains high for months after the infection, while ASO titers decline after a few weeks.

Also, ASO is usually high in strep throat cases, while anti-DNAase B is higher in strep skin infections.

-Ay doc, the baby is cynosed and doesn't get enough oxygen
- let's punch a hole in his heart 😂

Battle sign indicates skull base or sphenoid fracture

Tirzepatide (GIP/GLP-1 agonist) for the treatment of DM-2 and weight loss

It's given as a subcutaneous injection once a week

It's a rare complication of bacterial pharyngitis/tonsillitis and involves an extension of the infection into the lateral pharyngeal spaces of the neck with subsequent septic thrombophlebitis of the internal jugular vein.

The bacteria involved is usually the anaerobic Fusobacterium necrophorum. And its most dangerous complication is thrombosis, which can cause stroke.

Paraneoplastic syndromes are very difficult to diagnose as they can pre-date definite cancer diagnosis by months or years (e.g. Lambert Eaton myasthenic syndrome, as the most legendary example of paraneoplastic syndrome).

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the concept of VOMIT (Victim of Medical/or Modern Imaging Technology) was put forth to prevent patients from needless diagnostic costs and mental anguish after being put through a battery of expensive and misdirected imaging tests.

That was fun to read

"The internet is the most potent anxiety provoking system ever devised"

A 15 year old girl complains of back pain. A neurological examination and various blood and radiological examinations are negative—except for the MRI scan (“I'm sure there'll be nothing, but let's be certain”). The scan shows a mild focal dilatation of the central canal of the spinal cord over two vertebral levels in the mid-dorsal region. She is referred for a neurosurgical opinion with a presumed diagnosis of syringomyelia. Her parents surf the net. Now they know all about small muscle wasting, intractable pains, dissociated sensory loss, and the strong likelihood of progressive neurological deterioration. They also learn that a major spinal (or, worse still, craniospinal) operation is the only way to alter this gloomy prognosis. They arrive for the consultation shattered but resigned.

Since I just recovered from the flu... Let's talk about viruses: