Lab Rats In Lab Coats
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Lab Rats In Lab Coats
Reflex seizure
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This is a reflex seizure induced by nothing other than changing the baby's diapers
Lab Rats In Lab Coats
This is a reflex seizure induced by nothing other than changing the baby's diapers
You can see the change in the baby's facial expressions, a myoclonus of the right arm (0:15) and the tonic seizure in its lower limbs afterwards.
The absence of all three signs of fever, neck stiffness and altered mental state virtually eliminates the diagnosis of meningitis in immunocompetent individuals.
Here's smthn weird:
Lab Rats In Lab Coats
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The trigeminal nerve:
The cell bodies of the sensory fibres are located in the trigeminal ganglion. From the trigeminal ganglion, the main fibers (those responsible for touch, proprioception, and vibration) pass to the pons. but the pain and temperature pathways descend to the spinal cord, to around C2, where they make up the "spinal trigeminal nucleus." Then they ascend back into the thalamus.
Lab Rats In Lab Coats
The trigeminal nerve: The cell bodies of the sensory fibres are located in the trigeminal ganglion. From the trigeminal ganglion, the main fibers (those responsible for touch, proprioception, and vibration) pass to the pons. but the pain and temperature pathways…
باختصار: الألياف العصبية المسؤولة عن إحساس الألم والحرارة بالوجه، بدل ما تروح مباشرةً لجذع الدماغ، رح تنزل للحبل الشوكي (لحد تقريبًا C2) وراها ترجع تصعد للدماغ.
That's why ipsilateral facial numbness may occur with cervical cord lesions.
That's also why there's smthn called "trigeminal tractotomy" where a surgeon would damage the trigeminal spinal tract (and nucleus), thus causing facial numbness.

This operation is used in refractory trigeminal neuralgia (including refractory postherpetic pain).
Bell's phenomenon
Lab Rats In Lab Coats
Bell's phenomenon
Basically the cornea moves upward when the patient tries to close his eyes. It's a normal phenomenon and is seen in syncope, and in LMN facial palsy (since the patient cannot close his eyes, he reflexively moves the cornea upward to protect it) among others. It's valuable for determining whether the patient has psychogenic or real coma; in psychogenic coma, the patient still retains Bell's phenomenon. It's not very sensitive but can confirm the diagnosis.
The patient doesn't suffer from any particular respiratory problem.
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Oncolytic viruses (OVs)
Lab Rats In Lab Coats
Oncolytic viruses (OVs)
ذني فايروسات إلهن القدرة (إما بشكل طبيعي أو بالهندسة الجينية) على تدمير الخلايا السرطانية. صارت بمنتصف القرن الـ 20 عدة أبحاث على أكثر من فايروس (adenovirus, West-Nile, Dengue, Newcastle disease وغيرهن) بس النتائج ما جانت كلش واعدة لحد سنة 1991 لمّا طوّروا HSV معدّل جينيًا قادر على إصابة الخلايا السرطانية فقط بدون الخلايا الطبيعية وبدينا نطوّر من هذا العلاج لحدما صار عدنا أول علاج للسرطان بالفايروسات، إسمه كلش طايح حظه وما ينقري Talimogene Laherparepvec لدرجة حطوله إختصار (T-Vec). وافقت عليه الـ FDA لعلاج الحالات الشديدة من سرطان الجلد (الميلانوما).
هذا النوع من العلاج يسموه علاج مناعي فايروسي (Immunovirotherapy) لأن الفايروس وحده ما يكدر يقتل السرطان، بس هو يفعّل جهاز المناعة ويسوي شوية تغييرات بجينات ومُستقبِلات السرطان بحيث يصير أسهل على الجهاز المناعي أنْ يستهدفه.
على ذكر العلاجات الغريبة للسرطان: