Myasthenia gravis has a bimodal age-related onset, with onset in the second or third decades more common in women and onset in the sixth or seventh decades more common in men.
Forwarded from Lab Rats In Lab Coats
Never treat megaloblastic anemia with folate before making sure the patient doesn't have B12 deficiency
Forwarded from Sado zone
Till you're fairly sure which is which
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The abduction paradox
With a complete rotator cuff tear, after the pain subsides, the clinical picture becomes unmistakable: active abduction is impossible and attempting it produces a characteristic shrug; but passive abduction is full and once the arm has been lifted above a right angle the patient can keep it up by using the deltoid (the ‘abduction paradox’); when they lower it sideways it suddenly drops (the ‘drop arm sign’).
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CPP = MAP – ICP
CPP: Cerebral Perfusion Pressure
MAP: Mean Arterial Pressure
ICP: IntraCranial Pressure
MAP: Mean Arterial Pressure
ICP: IntraCranial Pressure
Lab Rats In Lab Coats
CPP = MAP – ICP
أكو شي إسمه الـ perfusion pressure اللي هو ضغط الدم اللي يحتاجه كل عضو حتى يشتغل بشكل فعال.
الدماغ يحتاج CPP بين 50 و 150 ملم زئبقي حتى يشتغل. هذا الـ CPP يعتمد على عاملين ذكرتهن بالمعادلة، وهو مهم كلش لأن إذا يقل، معناها رح تصير ischemia.
الدماغ يحتاج CPP بين 50 و 150 ملم زئبقي حتى يشتغل. هذا الـ CPP يعتمد على عاملين ذكرتهن بالمعادلة، وهو مهم كلش لأن إذا يقل، معناها رح تصير ischemia.
So, for example, if ICP rises to high levels, this can reduce the CPP and cause brain ischemia.
The same applies for the ISP (IntraSpinal Pressure).
Historically, gout has been described as sudden and severe pain in the big toe, often striking in the middle of the night. That’s often true for men, but women tend to develop gout in several joints slowly over time. It may show up in their knees, toes, wrists and ends of their fingers, where they may already some damage from osteoarthritis. This can be a problem because it means gout in the hands is often misdiagnosed.
Also, women rarely develop gout prior to menopause due to the protective effect of estrogen.