Lab Rats In Lab Coats
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Lab Rats In Lab Coats
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From 'The Anatomy of The Human Gravid Uterus' by William Hunter.
Lab Rats In Lab Coats
The Anatomy of The Human Gravid Uterus .pdf
It has cool, old anatomical illustrations
Livedo reticularis
Lab Rats In Lab Coats
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It's reddish, bluish, or purple discoloration of the skin in a net-like pattern. It is due to venodilation of the superficial veins of the skin & an increase in deoxygenated blood in the skin.
LR also has a significant relationship with anti-phospholipid syndrome (which itself has a significant correlation with SLE) where up to 40% of patients present with LR as the first sign.
Cardiac x-ray notes:
• The ventricles respond to obstruction to their outflow by first undergoing hypertrophy rather than dilatation. Therefore the heart may not appear enlarged at first with lesions like aortic stenosis, coarctation of the aorta, pulmonic stenosis, or systemic hypertension. When the ventricular wall becomes thicker, the lumen actually becomes smaller, and it is only when the muscle begins to fail and the heart decompensates that the heart visibly enlarges.
Lab Rats In Lab Coats
Cardiac x-ray notes: • The ventricles respond to obstruction to their outflow by first undergoing hypertrophy rather than dilatation. Therefore the heart may not appear enlarged at first with lesions like aortic stenosis, coarctation of the aorta, pulmonic…
• Cardiomegaly, as recognized on chest radiographs, is primarily produced by ventricular enlargement, not by isolated enlargement of the atria. Therefore the heart usually appears normal in size in early mitral stenosis, even though the left atrium is enlarged.
Lab Rats In Lab Coats
Cardiac x-ray notes: • The ventricles respond to obstruction to their outflow by first undergoing hypertrophy rather than dilatation. Therefore the heart may not appear enlarged at first with lesions like aortic stenosis, coarctation of the aorta, pulmonic…
• In general, the most marked chamber enlargement will occur from volume overload rather than pressure overload, so that the largest chambers are usually produced by regurgitant valves rather than stenotic valves. Therefore the heart will usually be larger with aortic regurgitation than aortic stenosis, and the left atrium will usually be larger in mitral regurgitation than mitral stenosis
Left: Aortic stenosis with no cardiomegaly
Right: Aortic regurgitation with cardiomegaly
Some folks systematically look at imaging studies, such as chest  radiographs, from the outside of the image to the inside of the  image; others look at them from the inside out or from top to bottom. Some systems for reminding you to examine every part of an image have catchy acronyms and mnemonics.
The fact is: It does not matter which system you use, as long as you look at everything on the image. So, use whichever system works for you, but be sure to look at everything. “Looking at  everything,” by the way, includes looking at all of the views available in a given study, not just everything on one view. (Do not forget that lateral chest radiograph in a two-view study of the chest.) Experienced radiologists usually have no system at all. Burned-in images are bad for computer monitors, but they are great for radiologists. “Burned” into the neurons of a radiologist’s  brain are mental images of what a normal frontal chest radiograph looks like, what thoracic sarcoidosis looks like, and so on. They frequently use a “gestalt” impression of a study that  they see in their mind’s eye within seconds of looking at an image. If the image does or does not correspond to the mental image that resides in their brains, then they systematically study the images. This is not magic; this ability comes only with experience, so at least for now, you are probably not quite ready to use the gestalt approach.
You only see what you look for, and you only look for what you know.
Although folate is present in nearly all foods, it is destroyed by 10 to 15 minutes of cooking, and as a result folate stores are marginal in a surprising number of healthy persons.
Lab Rats In Lab Coats
Although folate is present in nearly all foods, it is destroyed by 10 to 15 minutes of cooking, and as a result folate stores are marginal in a surprising number of healthy persons.
Vitamin B12 is widely present in foods, is resistant to cooking and boiling, and is even synthesized by gut flora.
Thus, unlike folate, vitamin B12 deficiency is virtually never caused by inadequate intake except in vegetarians who scrupulously avoid milk and eggs. Instead, deficiencies typically arise from some abnormality that interferes with vitamin B12 absorption.
Non-megaloblastic, macrocytic anemia (MCV>100 fL)
Lab Rats In Lab Coats
Non-megaloblastic, macrocytic anemia (MCV>100 fL)
Caused by alcoholism, hyperlipidemia, hypothyroidism, and liver disease.
Lab Rats In Lab Coats
Non-megaloblastic, macrocytic anemia (MCV>100 fL)
The red cell membrane is composed of a lipid bilayer that will freely exchange with the plasma pool of lipid. Conditions such as liver disease, hypothyroidism, hyperlipidemia and pregnancy are associated with raised lipids and may cause a raised MCV, but is usually less than 110 fL (unlike in megaloblastic anemia, which causes MCV >110 fL)
Why Iron deficiency causes microcytosis (cells smaller than normal)?
This is because the maturing red cells undergo an extra cellular division before the critical haemoglobin concentration required to arrest mitosis is achieved. The cells are also hypochromic, with a larger area of central pallor