Gastrulation (embryology)

Development of myelinated vs unmyelinated neurons

اليوم اولمرة بحياتي

اقرة امبريو
ومحاضرتين قريت هم يعني

Look at this lil dudeee

اكثر شي انصدمت بي
الlungs يطلعن من الesophagus
حرفيا ينمن منعدة
وبعدين الملحد يكلك الله شون خلق حواء من ضلع ادم

Now I wanna make an embryology textbook and name it:

How to make a human at home (DIY tutorial)

+ اتفق
ابو الجراحة كال البارحة أنّ البشر عبارة عن پليتة plate مطوية على روحها، مثل الأوريكامي

وهنا طخت ببالي الا اتعلم امبريو

It's a common, but poorly understood, gynecological condition that affects women of all age groups. It is defined as the presence of ectopic nests of endometrial glands and stroma within the myometrium, surrounded by reactive smooth muscle hyperplasia. Adenomyosis is a common cause of dysmenorrhea, menorrhagia, and chronic pelvic pain, but is often underdiagnosed.

It's a thrombotic microangiopathy (TMA) caused by severely reduced activity of the von Willebrand factor-cleaving protease ADAMTS13. It is characterized by arteriolar platelet-rich thrombi that cause organ ischemia and produce neurologic abnormalities, kidney dysfunction, thrombocytopenia, and microangiopathic hemolytic anemia (MAHA).

Of all TTP, >90 percent is immune, caused by autoantibody-mediated inhibition of ADAMTS13 activity or clearance of ADAMTS13 protein.

MAHA & Thrombocytopenia are the hallmarks of TTP and should warrant suspicion of TTP in a patient with no alternative explanation.

Microangiopathic hemolytic anemia (MAHA) results from mechanical shearing (fragmentation) of RBCs as they pass through platelet-rich microthrombi in the microvasculature; it is documented by the finding of prominent schistocytes, including helmet cells and triangular cells, on the peripheral blood smear.

More on bleeding

Platelet/vessel wall defects cause spontaneous purpura in the skin and mucous membranes or immediately after trauma. Coagulation defects cause haematomas and haemarthroses usually with a time delay after trauma. A positive family history or early onset of bleeding suggests haemophilia.

The distribution of bruising may suggest the diagnosis:
• Thrombocytopenic purpura is most evident over the ankles and pressure areas. Retinal haemorrhages tend to occur if there is a combination of severe thrombocytopenia and anaemia.
• Senile purpura and steroid-induced bruising occur mainly on the forearms and backs of the hands.
• Henoch–Schönlein purpura typically occurs over the extensor aspects of the limbs and buttocks.
• Scurvy causes bleeding from the gums and around the hair follicles.